MX9204815A - Hexahidrobenzo[f]quinolinonas y formulacion farmaceutica que las comprende. - Google Patents

Hexahidrobenzo[f]quinolinonas y formulacion farmaceutica que las comprende.

Info

Publication number
MX9204815A
MX9204815A MX9204815A MX9204815A MX9204815A MX 9204815 A MX9204815 A MX 9204815A MX 9204815 A MX9204815 A MX 9204815A MX 9204815 A MX9204815 A MX 9204815A MX 9204815 A MX9204815 A MX 9204815A
Authority
MX
Mexico
Prior art keywords
quinolinonas
hexahidrobenzo
pharmaceutical formulation
hexahydrobenzo
quinolin
Prior art date
Application number
MX9204815A
Other languages
English (en)
Inventor
Kenneth Steven Hirsch
Charles David Jones
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX9204815A publication Critical patent/MX9204815A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Fats And Perfumes (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

Esta invención se refiere a 1,2,3,4,5,6-hexahidrobenzo[f]quinolin-3-onas, a formulados farmacéuticos que contienen estos compuestos y a su uso como esteroides inhibidores de la 5 (mega)-reductasa.
MX9204815A 1991-08-21 1992-08-20 Hexahidrobenzo[f]quinolinonas y formulacion farmaceutica que las comprende. MX9204815A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74813491A 1991-08-21 1991-08-21
US07/780,166 US5250539A (en) 1991-08-21 1991-10-21 Hexahydrobenzo[f]quinolinones

Publications (1)

Publication Number Publication Date
MX9204815A true MX9204815A (es) 1993-12-01

Family

ID=27114886

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204815A MX9204815A (es) 1991-08-21 1992-08-20 Hexahidrobenzo[f]quinolinonas y formulacion farmaceutica que las comprende.

Country Status (17)

Country Link
US (1) US5250539A (es)
EP (1) EP0531026B1 (es)
JP (1) JPH05213889A (es)
KR (1) KR930004269A (es)
CN (1) CN1069488A (es)
AT (1) ATE173467T1 (es)
AU (1) AU2118292A (es)
BR (1) BR9203266A (es)
CA (1) CA2076509A1 (es)
CZ (1) CZ256792A3 (es)
DE (1) DE69227612T2 (es)
FI (1) FI923751A (es)
HU (1) HUT68064A (es)
IL (1) IL102880A0 (es)
MX (1) MX9204815A (es)
NO (1) NO923266L (es)
TW (1) TW218011B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239075A (en) * 1991-08-21 1993-08-24 Eli Lilly And Company Process for the preparation of benzo (f) quinolinones
AU654573B2 (en) * 1991-08-21 1994-11-10 Eli Lilly And Company Benzo(f)quinolinones
GB9317314D0 (en) * 1993-08-20 1993-10-06 Smithkline Beecham Corp Compounds
US5578724A (en) * 1994-09-20 1996-11-26 Eli Lilly And Company Process for preparation of benzo[f]quinolinones
FR2737721B1 (fr) 1995-08-08 1997-09-05 Roussel Uclaf Nouveaux composes biphenyles, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicament et les compositions pharmaceutiques les contenant
EP0926148A1 (en) 1997-12-23 1999-06-30 Applied Research Systems Ars Holding N.V. Benzo (C)quinolizine derivatives, their preparation and use as 5-alphareductases inhibitors
GB0222516D0 (en) * 2002-09-27 2002-11-06 Karobio Ab Novel compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0102046A1 (en) * 1982-08-26 1984-03-07 Schering Corporation Tricyclic lactams, method for making them, pharmaceutical compositions containing them
US4511569A (en) * 1982-08-26 1985-04-16 Schering Corporation Tricyclic lactams and derivatives useful in increasing cardiac contractility
US5120742A (en) * 1984-02-27 1992-06-09 Merck & Co., Inc. 17 β-acyl-4-aza-5 α-androst-1-ene-3-ones as 5 α-reductase inhibitors
US4859681A (en) * 1984-02-27 1989-08-22 Merck & Co., Inc. 17 α-Acyl-4-aza-5a-androst-1-en-3-ones as 5 alpha-reductase inhibitors
DE3773950D1 (de) * 1986-01-23 1991-11-28 Hoffmann La Roche Benzazecin-derivate.
US4888336A (en) * 1987-01-28 1989-12-19 Smithkline Beckman Corporation Steroid 5-alpha-reductase inhibitors
DE3872937T2 (de) * 1987-05-11 1993-01-21 Ono Pharmaceutical Co Benzoylaminophenoxybuttersaeure-derivate.
IN167395B (es) * 1987-07-21 1990-10-20 Hoffmann La Roche
US5120840A (en) * 1990-08-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. 4-amino-4-ene-steroids and their use as 5α-reductase inhibitors

Also Published As

Publication number Publication date
HUT68064A (en) 1995-05-29
BR9203266A (pt) 1993-04-06
EP0531026A1 (en) 1993-03-10
DE69227612D1 (de) 1998-12-24
IL102880A0 (en) 1993-01-31
FI923751A0 (fi) 1992-08-20
AU2118292A (en) 1993-02-25
CN1069488A (zh) 1993-03-03
NO923266L (no) 1993-02-22
DE69227612T2 (de) 1999-05-06
KR930004269A (ko) 1993-03-22
JPH05213889A (ja) 1993-08-24
FI923751A (fi) 1993-02-22
EP0531026B1 (en) 1998-11-18
NO923266D0 (no) 1992-08-20
US5250539A (en) 1993-10-05
CZ256792A3 (en) 1993-04-14
CA2076509A1 (en) 1993-02-22
ATE173467T1 (de) 1998-12-15
TW218011B (es) 1993-12-21

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