MX9204243A - Metodo para cristalizar el ester metilico de alfa-l-aspartil-l-fenilalanina. - Google Patents

Metodo para cristalizar el ester metilico de alfa-l-aspartil-l-fenilalanina.

Info

Publication number
MX9204243A
MX9204243A MX9204243A MX9204243A MX9204243A MX 9204243 A MX9204243 A MX 9204243A MX 9204243 A MX9204243 A MX 9204243A MX 9204243 A MX9204243 A MX 9204243A MX 9204243 A MX9204243 A MX 9204243A
Authority
MX
Mexico
Prior art keywords
methyl ester
phenylalanine methyl
aspartil
apm
crystallizing
Prior art date
Application number
MX9204243A
Other languages
English (en)
Inventor
Hidetaka Egashira
Yukio Takeshima
Kengo Okajima
Johannes Wounterus V Winfried
Tsugio Murakami
Original Assignee
Holland Sweetener Company
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Holland Sweetener Company, Tosoh Corp filed Critical Holland Sweetener Company
Publication of MX9204243A publication Critical patent/MX9204243A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un método para cristalizar el éster metílico de alfa-L-aspartil-L-fenilalanina (APM) de solución, mediante enfriamiento. En este método, los cristales de APM se precipitan mediante el enfriamiento de una solución de APM, a través de contacto directo con hielo.
MX9204243A 1991-07-19 1992-07-20 Metodo para cristalizar el ester metilico de alfa-l-aspartil-l-fenilalanina. MX9204243A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20370391 1991-07-19

Publications (1)

Publication Number Publication Date
MX9204243A true MX9204243A (es) 1994-02-28

Family

ID=16478456

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9204243A MX9204243A (es) 1991-07-19 1992-07-20 Metodo para cristalizar el ester metilico de alfa-l-aspartil-l-fenilalanina.

Country Status (8)

Country Link
EP (1) EP0523813B1 (es)
KR (1) KR930702384A (es)
AT (1) ATE145650T1 (es)
CA (1) CA2089359A1 (es)
DE (1) DE69215444T2 (es)
ES (1) ES2096708T3 (es)
MX (1) MX9204243A (es)
WO (1) WO1993002100A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000009984A (ko) * 1998-07-29 2000-02-15 고두모 알파-엘-아스파틸-엘-페닐알라닌 메틸 에스테르의 결정화 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2017137A1 (en) * 1989-05-22 1990-11-22 Shigeaki Irino Method for crystallizing &-l-aspartyl-l-phenylalanine methyl ester
JPH0327398A (ja) * 1989-06-26 1991-02-05 Mitsui Toatsu Chem Inc α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの晶析方法

Also Published As

Publication number Publication date
CA2089359A1 (en) 1993-01-20
WO1993002100A1 (en) 1993-02-04
ES2096708T3 (es) 1997-03-16
EP0523813B1 (en) 1996-11-27
EP0523813A1 (en) 1993-01-20
DE69215444T2 (de) 1997-06-12
KR930702384A (ko) 1993-09-08
DE69215444D1 (de) 1997-01-09
ATE145650T1 (de) 1996-12-15

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees