MX392374B - Peptidos terapeuticos relacionados con mots-c. - Google Patents
Peptidos terapeuticos relacionados con mots-c.Info
- Publication number
- MX392374B MX392374B MX2019003567A MX2019003567A MX392374B MX 392374 B MX392374 B MX 392374B MX 2019003567 A MX2019003567 A MX 2019003567A MX 2019003567 A MX2019003567 A MX 2019003567A MX 392374 B MX392374 B MX 392374B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- mots
- therapeutic peptides
- peptides related
- treating
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000016097 disease of metabolism Diseases 0.000 abstract 1
- 230000004129 fatty acid metabolism Effects 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
Abstract
La presente invención se refiere a péptidos y análogos peptídicos y métodos para tratar una enfermedad metabólica, por ejemplo, obesidad, diabetes, métodos para tratar cáncer, métodos para tratar una enfermedad hepática, y métodos para modular el metabolismo del ácido graso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662401123P | 2016-09-28 | 2016-09-28 | |
| PCT/US2017/053597 WO2018064098A1 (en) | 2016-09-28 | 2017-09-27 | Therapeutic mots-c related peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019003567A MX2019003567A (es) | 2019-12-02 |
| MX392374B true MX392374B (es) | 2025-03-24 |
Family
ID=60164788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019003567A MX392374B (es) | 2016-09-28 | 2017-09-27 | Peptidos terapeuticos relacionados con mots-c. |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11111271B2 (es) |
| EP (1) | EP3519431A1 (es) |
| JP (1) | JP7035033B2 (es) |
| KR (1) | KR20190057110A (es) |
| CN (1) | CN110072883A (es) |
| AU (1) | AU2017336440B2 (es) |
| CA (1) | CA3038292A1 (es) |
| IL (1) | IL265463A (es) |
| MX (1) | MX392374B (es) |
| TW (1) | TW201819398A (es) |
| WO (1) | WO2018064098A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018064098A1 (en) * | 2016-09-28 | 2018-04-05 | Cohbar, Inc. | Therapeutic mots-c related peptides |
| JP2021519321A (ja) * | 2018-03-27 | 2021-08-10 | コーバー、インコーポレイテッド | ペプチド含有製剤 |
| AU2018426503A1 (en) * | 2018-06-07 | 2021-01-21 | Hanyi Bio-Technology Company Ltd. | Pharmaceutical composition for preventing diabetes and use thereof |
| KR20210121132A (ko) * | 2019-01-28 | 2021-10-07 | 코바, 인크. | 치료용 펩티드 |
| CN110818804B (zh) * | 2019-10-21 | 2021-06-04 | 兰州大学 | 脑靶向肽及其在制备增强记忆药物中的应用 |
| CN115867648A (zh) * | 2020-02-14 | 2023-03-28 | 西北大学 | 将用于遗传密码重编程的化学底物扩展至包括长链碳和环状氨基酸 |
| IL303813A (en) | 2020-12-21 | 2023-08-01 | Univ Cornell | Peptide-linked drug delivery system |
| CN113440599A (zh) * | 2021-08-11 | 2021-09-28 | 南京市妇幼保健院 | MOTS-c肽及其衍生物在制备妊娠期糖尿病治疗药物中的应用 |
| CN113876929B (zh) * | 2021-11-22 | 2024-02-23 | 中国人民解放军陆军军医大学 | 肽MOTS-c在制备治疗帕金森药物中的应用 |
| CN115444926A (zh) * | 2022-05-10 | 2022-12-09 | 江南大学 | MOTS-c肽及其衍生物在制备放射性肺损伤治疗药物中的应用 |
| WO2023249904A1 (en) * | 2022-06-20 | 2023-12-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating diabetes |
| US12064467B2 (en) * | 2022-10-28 | 2024-08-20 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of humanin or other peptides |
| KR102741555B1 (ko) * | 2024-04-30 | 2024-12-13 | 주식회사 미토스테라퓨틱스 | 피부 투과도가 높은 미토콘드리아 유래 펩타이드를 포함하는 피부 주름 개선 또는 미백용 조성물 |
| CN119241659B (zh) * | 2024-10-08 | 2025-09-19 | 西北大学 | MOTS-c及其氨基酸突变多肽在伤口愈合方面的用途 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP0272253A4 (en) | 1986-03-07 | 1990-02-05 | Massachusetts Inst Technology | METHOD FOR IMPROVING GLYCOPROTE INSTABILITY. |
| US5846528A (en) | 1996-01-18 | 1998-12-08 | Avigen, Inc. | Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence |
| US5858351A (en) | 1996-01-18 | 1999-01-12 | Avigen, Inc. | Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors |
| US6015709A (en) | 1997-08-26 | 2000-01-18 | Ariad Pharmaceuticals, Inc. | Transcriptional activators, and compositions and uses related thereto |
| WO2001076532A2 (en) | 2000-04-11 | 2001-10-18 | Cogent Neuroscience, Inc. | Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death |
| AU6808001A (en) | 2000-05-23 | 2001-12-03 | Neurologix Inc | Glutamic acid decarboxylase (gad) based delivery systems |
| US7588757B2 (en) | 2001-03-14 | 2009-09-15 | Genzyme Corporation | Methods of treating Parkinson's disease using recombinant adeno-associated virus virions |
| PT2573170T (pt) | 2001-12-17 | 2018-03-26 | Univ Pennsylvania | Sequências de um vírus adenoassociado (aav) de serotipo 9, vetor contendo as mesmas, e suas utilizações |
| AU2003274397A1 (en) | 2002-06-05 | 2003-12-22 | University Of Florida | Production of pseudotyped recombinant aav virions |
| EP2368578A1 (en) | 2003-01-09 | 2011-09-28 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| US20040258666A1 (en) | 2003-05-01 | 2004-12-23 | Passini Marco A. | Gene therapy for neurometabolic disorders |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| WO2006119432A2 (en) | 2005-04-29 | 2006-11-09 | The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services | Isolation, cloning and characterization of new adeno-associated virus (aav) serotypes |
| EP1857552A1 (en) | 2006-05-20 | 2007-11-21 | Cargill Incorporated | Thermostable xylose isomerase enzyme |
| US7846445B2 (en) | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
| EP1986661B1 (en) | 2006-02-08 | 2018-08-29 | Genzyme Corporation | Gene therapy for niemann-pick disease type a |
| US7588772B2 (en) | 2006-03-30 | 2009-09-15 | Board Of Trustees Of The Leland Stamford Junior University | AAV capsid library and AAV capsid proteins |
| US8292769B2 (en) | 2006-11-22 | 2012-10-23 | Lawson Jr Thomas Towles | Transmission |
| US8309525B2 (en) | 2007-05-30 | 2012-11-13 | Albert Einstein College Of Medicine Of Yeshiva University | Treatment of type 2 diabetes, metabolic syndrome, myocardial injury and neurodegeneration with humanin and analogs thereof |
| CA2692392A1 (en) * | 2007-06-29 | 2009-01-08 | Centocor Ortho Biotech Inc. | Anti- mcp-1 antibodies, compositions, methods and uses |
| CN103298935A (zh) | 2007-08-15 | 2013-09-11 | 阿穆尼克斯公司 | 用于改善生物活性多肽性能的组合物和方法 |
| US7998928B2 (en) | 2007-09-14 | 2011-08-16 | The Regents Of The University Of California | Method of treatment of type-1 diabetes with a humanin analogue |
| TWI541020B (zh) | 2008-04-17 | 2016-07-11 | 巴克斯歐塔公司 | 生物活性胜肽 |
| US8637470B2 (en) | 2008-05-01 | 2014-01-28 | The Regents Of The University Of California | Small humanin-like peptides |
| US9217155B2 (en) | 2008-05-28 | 2015-12-22 | University Of Massachusetts | Isolation of novel AAV'S and uses thereof |
| AU2009327418A1 (en) | 2008-12-19 | 2010-06-24 | Indiana University Research And Technology Corporation | Amide based glucagon superfamily peptide prodrugs |
| SG10201908848RA (en) | 2010-03-29 | 2019-10-30 | Univ Pennsylvania | Pharmacologically induced transgene ablation system |
| DK2826860T3 (en) | 2010-04-23 | 2018-12-03 | Univ Massachusetts | CNS targeting AAV vectors and methods for their use |
| WO2012009709A1 (en) * | 2010-07-16 | 2012-01-19 | Sudhir Paul | Hiv cd4 binding site based covalent immunogen compositions |
| EP2634253B1 (en) | 2010-10-27 | 2016-05-11 | Jichi Medical University | Adeno-associated virus virions for transferring genes into neural cells |
| JP6091435B2 (ja) | 2011-02-22 | 2017-03-08 | カリフォルニア インスティチュート オブ テクノロジー | アデノ随伴ウイルス(aav)ベクターを用いたタンパク質の送達 |
| US20130123168A1 (en) | 2011-06-17 | 2013-05-16 | The Regents Of The University Of California | Humanin and humanin-analogues for the management of atherosclerosis |
| EP2986314A4 (en) | 2013-03-15 | 2016-04-13 | Univ Indiana Res & Tech Corp | PRODRUGS WITH EXTENDED EFFECT |
| BR112015023500B1 (pt) * | 2013-03-15 | 2021-01-12 | The Regents Of The University Of California | composição farmacêutica |
| CA2912678C (en) | 2013-05-15 | 2023-10-10 | Regents Of The University Of Minnesota | Adeno-associated virus mediated gene transfer to the central nervous system |
| WO2015168666A2 (en) | 2014-05-02 | 2015-11-05 | Genzyme Corporation | Aav vectors for retinal and cns gene therapy |
| CN112553229A (zh) | 2014-11-05 | 2021-03-26 | 沃雅戈治疗公司 | 用于治疗帕金森病的aadc多核苷酸 |
| MA41451A (fr) | 2015-02-04 | 2017-12-12 | Univ Washington | Constructions anti-tau |
| WO2018064098A1 (en) | 2016-09-28 | 2018-04-05 | Cohbar, Inc. | Therapeutic mots-c related peptides |
-
2017
- 2017-09-27 WO PCT/US2017/053597 patent/WO2018064098A1/en not_active Ceased
- 2017-09-27 AU AU2017336440A patent/AU2017336440B2/en not_active Ceased
- 2017-09-27 KR KR1020197012168A patent/KR20190057110A/ko not_active Ceased
- 2017-09-27 MX MX2019003567A patent/MX392374B/es unknown
- 2017-09-27 EP EP17788342.8A patent/EP3519431A1/en not_active Withdrawn
- 2017-09-27 CN CN201780059877.XA patent/CN110072883A/zh active Pending
- 2017-09-27 TW TW106133165A patent/TW201819398A/zh unknown
- 2017-09-27 JP JP2019517875A patent/JP7035033B2/ja not_active Expired - Fee Related
- 2017-09-27 CA CA3038292A patent/CA3038292A1/en active Pending
- 2017-09-27 US US16/336,089 patent/US11111271B2/en not_active Expired - Fee Related
-
2019
- 2019-03-19 IL IL265463A patent/IL265463A/en unknown
-
2021
- 2021-08-04 US US17/393,944 patent/US11332497B2/en active Active
-
2022
- 2022-04-11 US US17/717,982 patent/US11753445B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017336440B2 (en) | 2022-06-02 |
| US11753445B2 (en) | 2023-09-12 |
| US11111271B2 (en) | 2021-09-07 |
| JP2020501514A (ja) | 2020-01-23 |
| US20200181197A1 (en) | 2020-06-11 |
| WO2018064098A1 (en) | 2018-04-05 |
| TW201819398A (zh) | 2018-06-01 |
| US20220242912A1 (en) | 2022-08-04 |
| US20210363187A1 (en) | 2021-11-25 |
| CA3038292A1 (en) | 2018-04-05 |
| EP3519431A1 (en) | 2019-08-07 |
| MX2019003567A (es) | 2019-12-02 |
| JP7035033B2 (ja) | 2022-03-14 |
| CN110072883A (zh) | 2019-07-30 |
| US11332497B2 (en) | 2022-05-17 |
| IL265463A (en) | 2019-05-30 |
| AU2017336440A1 (en) | 2019-04-11 |
| KR20190057110A (ko) | 2019-05-27 |
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