MX382809B - Uso de tm9sf4 como un biomarcador para exosomas asociadas con tumores. - Google Patents
Uso de tm9sf4 como un biomarcador para exosomas asociadas con tumores.Info
- Publication number
- MX382809B MX382809B MX2016016122A MX2016016122A MX382809B MX 382809 B MX382809 B MX 382809B MX 2016016122 A MX2016016122 A MX 2016016122A MX 2016016122 A MX2016016122 A MX 2016016122A MX 382809 B MX382809 B MX 382809B
- Authority
- MX
- Mexico
- Prior art keywords
- tm9sf4
- extracellular vesicles
- biomarker
- tumor
- isolating
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a un método para determinar in vitro la presencia de un tumor en un sujeto, el método comprende: a) proporcionar una muestra biológica obtenida a partir de ese sujeto, b) aislar vesículas extracelulares a partir de la muestra, en donde esta etapa de aislamiento de vesículas extracelulares comprende el aislamiento de vesículas extracelulares positivas a TM9SF4, c) determinar, a partir de las vesículas extracelulares aisladas en la etapa b), el nivel o presencia de un biomarcador adecuado, y d) comparar el nivel o presencia del biomarcador determinado en la etapa c) con uno de referencia, caracterizado porque las vesículas extracelulares positivas a TM9SF4 se aíslan a través de la unión a un anticuerpo anti-TM9SF4.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14171464 | 2014-06-06 | ||
| PCT/EP2015/062594 WO2015185730A2 (en) | 2014-06-06 | 2015-06-05 | Exosomal biomarkers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016016122A MX2016016122A (es) | 2017-04-27 |
| MX382809B true MX382809B (es) | 2025-03-13 |
Family
ID=50896184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016016122A MX382809B (es) | 2014-06-06 | 2015-06-05 | Uso de tm9sf4 como un biomarcador para exosomas asociadas con tumores. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20170146543A1 (es) |
| EP (1) | EP3152576B1 (es) |
| JP (1) | JP6650929B2 (es) |
| CN (2) | CN113092764A (es) |
| AU (1) | AU2015270450B2 (es) |
| CA (1) | CA2950977C (es) |
| ES (1) | ES2700404T3 (es) |
| MX (1) | MX382809B (es) |
| PL (1) | PL3152576T3 (es) |
| RU (1) | RU2712223C2 (es) |
| WO (1) | WO2015185730A2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018070479A1 (ja) * | 2016-10-13 | 2018-04-19 | 合同会社みらか中央研究所 | 細胞外小胞の回収方法 |
| CN110869513B (zh) * | 2017-06-21 | 2024-01-26 | 外索米克斯股份公司 | 与ca-ix阳性外来体捕获有关的方法和试剂盒 |
| RU2020117183A (ru) | 2017-12-14 | 2021-11-25 | Сони Корпорейшн | Устройство связи, способ связи и программа |
| AU2019240901B2 (en) * | 2018-03-30 | 2025-07-17 | Exosomics S.p.A. | Use of hollow fibers to obtain blood or a blood derivative impoverished from blood cells and platelets derived extracellular vesicles |
| RU2705344C1 (ru) * | 2019-03-15 | 2019-11-06 | Ольга Алексеевна Фишер | Способ скрининга рака молочной железы и предрасположенности к нему |
| US20230243834A1 (en) * | 2020-01-17 | 2023-08-03 | Mercy Bioanalytics, Inc. | Compositions and methods for detection of ovarian cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8617806B2 (en) * | 2008-01-25 | 2013-12-31 | Hansabiomed Ou | Method to measure and characterize microvesicles in the human body fluids |
| US20120058492A1 (en) * | 2008-01-25 | 2012-03-08 | Hansabiomed Ou | Method and a Kit To Detect Malignant Tumors and Provide a Prognosis |
| US20120122118A1 (en) * | 2008-01-25 | 2012-05-17 | Primm Srl | Monclonal antibodies, hybridomas and methods for use |
| ES2587055T3 (es) * | 2008-01-25 | 2016-10-20 | Hansabiomed Ou | Una nueva molécula asociada a tumores humanos metastásicos, métodos para detectar tanto el gen activado como la proteína y para interferir con la expresión génica |
| CN107254538A (zh) * | 2008-11-12 | 2017-10-17 | 卡里斯生命科学瑞士控股有限责任公司 | 使用外来体来确定表现型的方法和系统 |
| AU2011316477A1 (en) * | 2010-10-11 | 2013-05-02 | Medsaic Pty Ltd | Assay for disease detection |
| CN103197066B (zh) * | 2013-03-07 | 2015-12-23 | 美国纳米材料创新有限公司 | 一种免疫脂质体生物芯片、其制备方法及其在生物检测中的应用 |
-
2015
- 2015-06-05 CN CN202110389013.2A patent/CN113092764A/zh active Pending
- 2015-06-05 JP JP2017516203A patent/JP6650929B2/ja active Active
- 2015-06-05 MX MX2016016122A patent/MX382809B/es unknown
- 2015-06-05 ES ES15726199T patent/ES2700404T3/es active Active
- 2015-06-05 AU AU2015270450A patent/AU2015270450B2/en active Active
- 2015-06-05 WO PCT/EP2015/062594 patent/WO2015185730A2/en not_active Ceased
- 2015-06-05 PL PL15726199T patent/PL3152576T3/pl unknown
- 2015-06-05 RU RU2016152346A patent/RU2712223C2/ru active
- 2015-06-05 US US15/316,188 patent/US20170146543A1/en not_active Abandoned
- 2015-06-05 EP EP15726199.1A patent/EP3152576B1/en active Active
- 2015-06-05 CN CN201580042674.0A patent/CN106574928A/zh active Pending
- 2015-06-05 CA CA2950977A patent/CA2950977C/en active Active
-
2022
- 2022-05-05 US US17/737,453 patent/US20220349892A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2016152346A3 (es) | 2019-03-18 |
| CN106574928A (zh) | 2017-04-19 |
| RU2712223C2 (ru) | 2020-01-27 |
| AU2015270450B2 (en) | 2021-04-01 |
| WO2015185730A2 (en) | 2015-12-10 |
| CA2950977C (en) | 2023-10-10 |
| AU2015270450A1 (en) | 2017-01-05 |
| US20220349892A1 (en) | 2022-11-03 |
| JP2017518517A (ja) | 2017-07-06 |
| EP3152576A2 (en) | 2017-04-12 |
| JP6650929B2 (ja) | 2020-02-19 |
| PL3152576T3 (pl) | 2019-01-31 |
| ES2700404T3 (es) | 2019-02-15 |
| MX2016016122A (es) | 2017-04-27 |
| RU2016152346A (ru) | 2018-07-09 |
| CN113092764A (zh) | 2021-07-09 |
| EP3152576B1 (en) | 2018-09-12 |
| US20170146543A1 (en) | 2017-05-25 |
| CA2950977A1 (en) | 2015-12-10 |
| BR112016028581A2 (en) | 2018-01-30 |
| WO2015185730A3 (en) | 2016-02-18 |
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