MX374804B - Proceso para extraer glucósidos cardíacos y composiciones. - Google Patents

Proceso para extraer glucósidos cardíacos y composiciones.

Info

Publication number
MX374804B
MX374804B MX2018008897A MX2018008897A MX374804B MX 374804 B MX374804 B MX 374804B MX 2018008897 A MX2018008897 A MX 2018008897A MX 2018008897 A MX2018008897 A MX 2018008897A MX 374804 B MX374804 B MX 374804B
Authority
MX
Mexico
Prior art keywords
compositions
cardiac glycosides
extracting cardiac
methods
extracting
Prior art date
Application number
MX2018008897A
Other languages
English (en)
Inventor
Donald Smothers
Original Assignee
Nerium Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerium Biotechnology Inc filed Critical Nerium Biotechnology Inc
Publication of MX374804B publication Critical patent/MX374804B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención pertenece a métodos para extraer glucósidos cardíacos del material de origen vegetal que contiene el glucósido cardíaco, como el Nerium oleander, a través del uso del áloe. Adicionalmente proporciona composiciones que resultan a partir de las extracciones, composiciones farmacéuticas, composiciones cosméticas, y métodos para tratar afecciones cutáneas.
MX2018008897A 2008-10-14 2009-10-13 Proceso para extraer glucósidos cardíacos y composiciones. MX374804B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10513308P 2008-10-14 2008-10-14
PCT/US2009/060523 WO2010045243A1 (en) 2008-10-14 2009-10-13 Process for extracting cardiac glycodides and compositions

Publications (1)

Publication Number Publication Date
MX374804B true MX374804B (es) 2025-03-06

Family

ID=41434085

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011003940A MX2011003940A (es) 2008-10-14 2009-10-13 Proceso para extraer glucosidos cardiacos y composiciones.
MX2018008897A MX374804B (es) 2008-10-14 2009-10-13 Proceso para extraer glucósidos cardíacos y composiciones.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2011003940A MX2011003940A (es) 2008-10-14 2009-10-13 Proceso para extraer glucosidos cardiacos y composiciones.

Country Status (11)

Country Link
US (3) US8524286B2 (es)
EP (1) EP2346518B1 (es)
JP (1) JP5727934B2 (es)
KR (1) KR101717301B1 (es)
CN (1) CN102186487B (es)
AU (1) AU2009303460B9 (es)
CA (1) CA2739029C (es)
MX (2) MX2011003940A (es)
RU (1) RU2530654C2 (es)
WO (1) WO2010045243A1 (es)
ZA (1) ZA201102765B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101374571B (zh) * 2006-01-31 2013-07-17 托莱多大学 Na/K-ATP酶配体
US8283441B2 (en) 2006-10-31 2012-10-09 University Of Toledo Na+K+-ATPase-specific peptide inhibitors/activators of SRC and SRC family kinases
AU2009303460B9 (en) * 2008-10-14 2014-12-18 Nerium Biotechnology, Inc. Process for extracting cardiac glycodides and compositions
CA2774486C (en) 2009-09-16 2019-06-04 The University Of Toledo Hydroxy xanthone-based na/k atpase ligands useful in treating cardiac hypertrophy, and congestive heart failure
WO2011088208A1 (en) 2010-01-13 2011-07-21 The University Of Toledo Materials and methods related to sodium/potassium adenosine triphosphase and cholesterol
US8541382B2 (en) 2010-11-13 2013-09-24 Sirbal Ltd. Cardiac glycoside analogs in combination with emodin for cancer therapy
US8597695B1 (en) 2010-11-13 2013-12-03 Sirbal Ltd. Herbal combinations for treatment of a skin condition
US9066974B1 (en) 2010-11-13 2015-06-30 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US9095606B1 (en) 2010-11-13 2015-08-04 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US20170049835A1 (en) 2015-07-29 2017-02-23 Sirbal Ltd. Herbal Combinations For Treating Scalp Conditions
RU2017136415A (ru) * 2011-10-20 2019-02-08 Нериум Байотекнолоджи, Инк. Терапевтическая комбинация для лечения рака
US8865231B2 (en) 2012-12-11 2014-10-21 Avon Products, Inc. Hoya carnosa extracts and methods of use
US9265716B2 (en) 2012-12-11 2016-02-23 Avon Products, Inc. Hoya carnosa extracts and methods of use
WO2014163717A1 (en) * 2013-03-11 2014-10-09 Avon Products, Inc. Hoya carnosa extracts and methods of use
WO2015082950A1 (en) 2013-12-02 2015-06-11 Sirbal Ltd. Herbal combinations for treatment of a skin condition
US10307446B2 (en) 2014-03-21 2019-06-04 St&T International, Inc. Cannabis extraction method and compositions
CN109897083A (zh) * 2017-12-07 2019-06-18 天津中医药大学 强心苷类化合物及其制备方法与应用
MX2020010388A (es) * 2018-04-02 2020-10-22 Nerium Biotechnology Inc Extractos de nerium oleander de origen vegetal y metodos.
KR102464428B1 (ko) 2020-03-31 2022-11-04 피닉스 바이오테크놀러지 인코포레이티드. 코로나바이러스 감염 치료를 위한 방법 및 조성물
EP4295854A3 (en) 2020-03-31 2024-04-03 Phoenix Biotechnology, Inc. Method and compositions for treating coronavirus infection

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1394196A (en) * 1971-10-03 1975-05-14 Hisamitsu Pharmaceutical Co Process for isolating oleandrin from nerium odorum
US4917890A (en) * 1985-06-28 1990-04-17 Carrington Laboratories, Inc. Processes for preparation of aloe products, products produced thereby and compositions thereof
US4851224A (en) * 1986-06-05 1989-07-25 Carrington Laboratories, Inc. Process for preparation of aloe products
US4735935A (en) * 1985-12-17 1988-04-05 Carrington Laboratories, Inc. Process for preparation of aloe products products, produced thereby and compositions thereof
US4966892A (en) * 1982-05-07 1990-10-30 Carrington Laboratories, Inc. Processes for preparation of aloe products products produced thereby and compositions thereof
US4957907A (en) * 1985-06-28 1990-09-18 Carrington Laboratories Inc. Process for preparation of aloe products
US4959214A (en) * 1985-06-28 1990-09-25 Carrington Laboratories Inc. Processes for preparation of aloe products products produced thereby and compositions thereof
CA1299100C (en) * 1986-05-13 1992-04-21 Huseyin Ziya Ozel Extracts of nerium species, methods of preparation and use therefor
US5891855A (en) * 1996-02-12 1999-04-06 The Scripps Research Institute Inhibitors of leaderless protein export
WO1999019505A1 (en) * 1997-10-10 1999-04-22 Univera Pharmaceuticals, Inc. Process for the preparation of immunomodulatory polysaccharides from aloe
WO2000016793A1 (en) * 1998-09-24 2000-03-30 Ozelle Pharmaceuticals, Inc. Extract of nerium species, pharmaceutical composition thereof and methods for preparation thereof
CN1304756A (zh) * 2000-11-23 2001-07-25 金国林 治疗皮肤疾患的中药制剂及其制备方法
WO2002102395A1 (en) * 2001-06-18 2002-12-27 S.A.V Virex Co Ltd Nerium oleander extract, compositions containing the nerium oleander l. extract and a method of preparation of this extract
US20060205679A1 (en) * 2004-10-22 2006-09-14 Azaya Therapeutics, Inc. Topical and oral formulations of cardiac glycosides for treating skin diseases
JP2007008879A (ja) * 2005-06-30 2007-01-18 Yanbaru Green Health:Kk 抗腫瘍剤及びこれを含有する食品
US7402325B2 (en) * 2005-07-28 2008-07-22 Phoenix Biotechnology, Inc. Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
EP1803461A1 (en) * 2005-12-27 2007-07-04 Heinz-Herbert Fiebig Therapeutic use of an extract from the leaves of Nerium oleander
AU2009303460B9 (en) * 2008-10-14 2014-12-18 Nerium Biotechnology, Inc. Process for extracting cardiac glycodides and compositions
RU2017136415A (ru) * 2011-10-20 2019-02-08 Нериум Байотекнолоджи, Инк. Терапевтическая комбинация для лечения рака

Also Published As

Publication number Publication date
US20190233457A1 (en) 2019-08-01
MX2011003940A (es) 2011-06-21
AU2009303460A1 (en) 2010-04-22
ZA201102765B (en) 2018-11-28
RU2530654C2 (ru) 2014-10-10
US20100092585A1 (en) 2010-04-15
RU2011113151A (ru) 2012-11-27
JP5727934B2 (ja) 2015-06-03
KR20110073570A (ko) 2011-06-29
US10323055B2 (en) 2019-06-18
US20130303470A1 (en) 2013-11-14
AU2009303460B2 (en) 2014-09-25
KR101717301B1 (ko) 2017-03-16
CA2739029A1 (en) 2010-04-22
US8524286B2 (en) 2013-09-03
WO2010045243A1 (en) 2010-04-22
JP2012505894A (ja) 2012-03-08
CN102186487A (zh) 2011-09-14
EP2346518B1 (en) 2020-09-02
EP2346518A1 (en) 2011-07-27
CN102186487B (zh) 2013-05-15
CA2739029C (en) 2018-07-10
AU2009303460B9 (en) 2014-12-18

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