MX373872B - Composiciones de isoxazolina y uso de las mismas en la prevención o tratamiento de infestaciones parasitarias en animales. - Google Patents

Composiciones de isoxazolina y uso de las mismas en la prevención o tratamiento de infestaciones parasitarias en animales.

Info

Publication number
MX373872B
MX373872B MX2016008118A MX2016008118A MX373872B MX 373872 B MX373872 B MX 373872B MX 2016008118 A MX2016008118 A MX 2016008118A MX 2016008118 A MX2016008118 A MX 2016008118A MX 373872 B MX373872 B MX 373872B
Authority
MX
Mexico
Prior art keywords
animals
prevention
treatment
parasite infestations
isoxazoline
Prior art date
Application number
MX2016008118A
Other languages
English (en)
Spanish (es)
Other versions
MX2016008118A (es
Inventor
Anne Lehay
Annie Flochlay-Sigognault
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of MX2016008118A publication Critical patent/MX2016008118A/es
Publication of MX373872B publication Critical patent/MX373872B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/132Heterocyclic compounds containing only one nitrogen as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/137Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MX2016008118A 2013-12-20 2014-12-19 Composiciones de isoxazolina y uso de las mismas en la prevención o tratamiento de infestaciones parasitarias en animales. MX373872B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13199006 2013-12-20
PCT/EP2014/078634 WO2015091898A1 (en) 2013-12-20 2014-12-19 Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals

Publications (2)

Publication Number Publication Date
MX2016008118A MX2016008118A (es) 2016-09-16
MX373872B true MX373872B (es) 2020-03-26

Family

ID=49880542

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016008118A MX373872B (es) 2013-12-20 2014-12-19 Composiciones de isoxazolina y uso de las mismas en la prevención o tratamiento de infestaciones parasitarias en animales.

Country Status (11)

Country Link
US (4) US10456358B2 (enExample)
EP (2) EP4306168B1 (enExample)
JP (1) JP6581586B2 (enExample)
CN (2) CN105813651B (enExample)
ES (2) ES3036365T3 (enExample)
HU (1) HUE066811T2 (enExample)
MX (1) MX373872B (enExample)
PL (2) PL3082867T3 (enExample)
PT (1) PT4306168T (enExample)
RU (1) RU2688919C1 (enExample)
WO (1) WO2015091898A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015091898A1 (en) 2013-12-20 2015-06-25 Intervet International B.V. Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
PL3236960T3 (pl) * 2014-12-22 2025-07-07 Intervet International B.V. Fluralaner do zastosowania w leczeniu demodekozy
BR112017027855B1 (pt) 2015-06-23 2022-11-16 Intervet International B.V. Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação
WO2018039508A1 (en) * 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
KR20190091268A (ko) * 2016-10-31 2019-08-05 더 스크립스 리서치 인스티튜트 매개체 전파 질환의 전염을 예방하기 위한 방법 및 조성물
AU2018363686B2 (en) * 2017-11-07 2023-11-23 Intervet International B.V. Process for preparing large size isoxazoline particles
PE20201150A1 (es) * 2017-11-07 2020-10-26 Intervet Int Bv Composiciones farmaceuticas inyectables de isoxazolina y usos de las mismas
KR20250065422A (ko) 2017-12-15 2025-05-12 타르서스 파마수티칼스, 아이엔씨. 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법
CN111511203B (zh) * 2017-12-20 2023-04-04 英特维特国际股份有限公司 用于水产养殖中的鱼外部寄生虫监测的方法和系统
WO2019121900A1 (en) 2017-12-20 2019-06-27 Intervet Inc. Method and system for external fish parasite monitoring in aquaculture
CA3084304A1 (en) * 2017-12-20 2019-06-27 Intervet International B.V. System for external fish parasite monitoring in aquaculture
CA3084294A1 (en) 2017-12-20 2019-06-27 Intervet International B.V. System for external fish parasite monitoring in aquaculture
CA3084287A1 (en) 2017-12-20 2019-06-27 Intervet International B.V. System for external fish parasite monitoring in aquaculture
KR102142916B1 (ko) * 2018-08-17 2020-08-10 부산대학교 산학협력단 상향식 방법을 통한 난용성 약물을 포함하는 나노현탁액의 제조방법 및 이로 제조된 나노현탁액
US20220249445A1 (en) * 2019-06-19 2022-08-11 Tarsus Pharmaceuticals, Inc. Isoxazoline parasiticide formulations and methods for treating blepharitis
EP3986377A4 (en) * 2019-06-19 2023-07-19 Tarsus Pharmaceuticals, Inc. Isoxazoline parasiticide formulations and methods for treating blepharitis
JP7724845B2 (ja) 2020-07-24 2025-08-18 エランコ・ユーエス・インコーポレイテッド イソオキサゾリン化合物及びその中間体を作製するための方法
CN114306231B (zh) * 2021-12-29 2023-03-24 天津市中升挑战生物科技有限公司 一种氟雷拉纳杀虫剂及其制备方法和应用
CN117064851A (zh) * 2023-09-20 2023-11-17 中国农业大学 一种异噁唑啉类驱虫药制剂的制备方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3727648A1 (de) 1987-08-19 1989-03-02 Bayer Ag Neue avermectin derivate, verfahren zu ihrer herstellung und ihre verwendung
US6998131B2 (en) * 1996-09-19 2006-02-14 Merial Limited Spot-on formulations for combating parasites
CN1930136B (zh) 2004-03-05 2012-02-08 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物及有害生物防除剂
AU2006313007C1 (en) * 2005-11-10 2019-10-03 Elanco Australasia Pty Limited Method of treating parasites
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2957284T3 (en) 2007-06-27 2018-02-05 Du Pont PROCEDURE TO CHECK ANIMALS FOR ANIMALS
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
KR101680912B1 (ko) * 2008-07-09 2016-11-29 바스프 에스이 이속사졸린 화합물 ⅰ을 포함하는 살충 활성 혼합물
KR101963426B1 (ko) 2008-07-09 2019-03-28 닛산 가가쿠 가부시키가이샤 이속사졸린 치환 안식향산 아미드 화합물의 제조 방법
KR101660068B1 (ko) * 2008-11-19 2016-09-26 메리얼 인코포레이티드 기생충 감염 치료를 위한 1-아릴피라졸 단독 또는 포름아미딘과의 조합을 포함하는 조성물
CA2747060A1 (en) 2008-12-18 2010-07-15 Novartis Ag Isoxazolines derivatives and their use as pesticide
NZ593135A (en) 2008-12-19 2013-04-26 Novartis Ag Isoxazoline derivatives and their use as pesticide
BR112012002164B1 (pt) 2009-07-30 2021-04-20 Merial, Inc compostos inseticidas de 4-amino-tieno[2,3-d]-pirimidina e métodos para seu uso
BR112012031093A8 (pt) 2010-06-09 2017-10-10 Syngenta Participations Ag Misturas de pesticidas incluindo derivados da isoxazolina
DK178277B1 (da) * 2010-06-18 2015-10-26 Novartis Tiergesundheit Ag Diaryloxazolinforbindelser til bekæmpelse af fiskelus
US9173870B2 (en) * 2010-12-27 2015-11-03 Intervet Inc. Topical localized isoxazoline formulation
RU2602189C2 (ru) * 2010-12-27 2016-11-10 Интервет Интернэшнл Б.В. Изоксазолиновый состав, содержащий гликофурол для наружного и местного применения
AU2012215440B2 (en) 2011-02-10 2015-08-27 Novartis Tiergesundheit Ag Isoxazoline derivatives for controlling invertebrate pests
PL2683723T3 (pl) 2011-03-10 2017-07-31 Zoetis Services Llc Spirocykliczne pochodne izoksazoliny jako środki przeciwpasożytnicze
US9247740B2 (en) 2011-08-25 2016-02-02 Syngenta Participations Ag Isoxazoline derivatives as insecticidal compounds
WO2013026695A1 (en) 2011-08-25 2013-02-28 Syngenta Participations Ag Isoxazoline derivatives as insecticidal compounds
PH12018501647A1 (en) * 2011-09-12 2019-02-27 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
KR20140075749A (ko) 2011-10-03 2014-06-19 신젠타 파티서페이션즈 아게 살곤충 화합물로서의 이속사졸린 유도체
BR112014024832B1 (pt) 2012-04-04 2022-05-31 Intervet International B.V. Método para a preparação de uma composição farmacêutica veterinária mastigável macia, composição farmacêutica, e, uso da composição
CN105579029B (zh) 2013-09-30 2019-03-05 硕腾服务有限责任公司 长效螺异恶唑啉制剂
HUE063842T2 (hu) 2013-12-20 2024-02-28 Intervet Int Bv Izoxazolin vegyületek felhasználása baromfiban
WO2015091898A1 (en) 2013-12-20 2015-06-25 Intervet International B.V. Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals

Also Published As

Publication number Publication date
HUE066811T2 (hu) 2024-09-28
JP2016540809A (ja) 2016-12-28
US20210353537A1 (en) 2021-11-18
EP4306168A3 (en) 2024-03-13
ES2971061T3 (es) 2024-06-03
MX2016008118A (es) 2016-09-16
US20200000720A1 (en) 2020-01-02
RU2019114223A (ru) 2019-06-28
CN105813651A (zh) 2016-07-27
PL3082867T3 (pl) 2024-05-13
RU2016129474A (ru) 2018-01-25
CN110327468A (zh) 2019-10-15
PL4306168T3 (pl) 2025-11-17
EP3082867A1 (en) 2016-10-26
US20240122849A1 (en) 2024-04-18
WO2015091898A1 (en) 2015-06-25
RU2688919C1 (ru) 2019-05-23
EP4306168B1 (en) 2025-06-25
EP4306168A2 (en) 2024-01-17
CN110327468B (zh) 2023-04-28
JP6581586B2 (ja) 2019-09-25
US20160317439A1 (en) 2016-11-03
ES3036365T3 (en) 2025-09-18
US11883530B2 (en) 2024-01-30
CN105813651B (zh) 2021-11-23
US10456358B2 (en) 2019-10-29
PT4306168T (pt) 2025-07-24
EP3082867B1 (en) 2024-01-17

Similar Documents

Publication Publication Date Title
MX373872B (es) Composiciones de isoxazolina y uso de las mismas en la prevención o tratamiento de infestaciones parasitarias en animales.
CY1124726T1 (el) Παραγωγα κιναζολινης που χρησιμοποιουνται για την αντιμετωπιση του hiv
PH12019550050A1 (en) Isoxazole analogs as fxr agonists and methods of use thereof
NZ733125A (en) Isoquinoline compounds for the treatment of hiv
MX387604B (es) Formulaciones cannabinoides estables.
CO2017002268A2 (es) Inhibidores espirocíclicos de catepsina c
DOP2015000274A (es) Compuestos químicos
EA201692301A1 (ru) Производные бороновой кислоты и их терапевтическое применение
MX2018001990A (es) Composiciones que comprenden un inhibidor de p13k y un inhibidor de hdac.
MX2019005082A (es) Composiciones que comprenden 15-ohepa y metodos para usar las mismas.
PH12016502353A1 (en) Pharmaceutical composition
KR102200014B9 (ko) 쿠메스트롤을 포함하는 콩 추출물을 유효성분으로 포함하는 갱년기 증상의 예방 및 치료용 조성물
MX383254B (es) Combinacion que comprende un glucocorticoide y edo-s101.
MX390051B (es) Antagonistas de ep4.
MX2017006709A (es) Agente para prevenir o mejorar sintomas causados por desequilibrio de las hormonas sexuales.
MX388592B (es) Compuestos y metodos terapeuticos.
MX2018005004A (es) Compuestos de indazol substituidos como inhibidores de rorgammat y sus usos.
UA115583C2 (uk) Азетидинілоксифенілпіролідинові сполуки
PH12016502480A1 (en) Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases
MX386902B (es) Metodos para el tratamiento de trastornos cardiovasculares.
TH1501006095A (th) องค์ประกอบของสารออกฤทธิ์ทางเภสัชกรรมที่ประกอบด้วย ไดเอธิลีน ไกลคอล โมโนเอธิล อีเธอร์ หรือ สารอนุพันธ์แอลคิลอื่นๆ

Legal Events

Date Code Title Description
FG Grant or registration