ES2971061T3 - Composiciones de isoxazolina y uso de las mismas en la prevención o el tratamiento de infestaciones parasitarias en animales - Google Patents

Composiciones de isoxazolina y uso de las mismas en la prevención o el tratamiento de infestaciones parasitarias en animales Download PDF

Info

Publication number
ES2971061T3
ES2971061T3 ES14815365T ES14815365T ES2971061T3 ES 2971061 T3 ES2971061 T3 ES 2971061T3 ES 14815365 T ES14815365 T ES 14815365T ES 14815365 T ES14815365 T ES 14815365T ES 2971061 T3 ES2971061 T3 ES 2971061T3
Authority
ES
Spain
Prior art keywords
pharmaceutical composition
drinking water
use according
animals
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14815365T
Other languages
English (en)
Spanish (es)
Inventor
Anne Lehay
Annie Flochlay-Sigognault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intervet International BV
Original Assignee
Intervet International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intervet International BV filed Critical Intervet International BV
Application granted granted Critical
Publication of ES2971061T3 publication Critical patent/ES2971061T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/132Heterocyclic compounds containing only one nitrogen as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/137Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ES14815365T 2013-12-20 2014-12-19 Composiciones de isoxazolina y uso de las mismas en la prevención o el tratamiento de infestaciones parasitarias en animales Active ES2971061T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13199006 2013-12-20
PCT/EP2014/078634 WO2015091898A1 (en) 2013-12-20 2014-12-19 Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals

Publications (1)

Publication Number Publication Date
ES2971061T3 true ES2971061T3 (es) 2024-06-03

Family

ID=49880542

Family Applications (2)

Application Number Title Priority Date Filing Date
ES14815365T Active ES2971061T3 (es) 2013-12-20 2014-12-19 Composiciones de isoxazolina y uso de las mismas en la prevención o el tratamiento de infestaciones parasitarias en animales
ES23206906T Active ES3036365T3 (en) 2013-12-20 2014-12-19 Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES23206906T Active ES3036365T3 (en) 2013-12-20 2014-12-19 Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals

Country Status (11)

Country Link
US (4) US10456358B2 (enExample)
EP (2) EP3082867B1 (enExample)
JP (1) JP6581586B2 (enExample)
CN (2) CN110327468B (enExample)
ES (2) ES2971061T3 (enExample)
HU (1) HUE066811T2 (enExample)
MX (1) MX373872B (enExample)
PL (2) PL4306168T3 (enExample)
PT (1) PT4306168T (enExample)
RU (1) RU2688919C1 (enExample)
WO (1) WO2015091898A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6581586B2 (ja) * 2013-12-20 2019-09-25 インターベット インターナショナル ベー. フェー. イソオキサゾリン組成物および動物における寄生虫侵襲の予防または処置におけるその使用
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
PL3236960T3 (pl) * 2014-12-22 2025-07-07 Intervet International B.V. Fluralaner do zastosowania w leczeniu demodekozy
HUE059228T2 (hu) * 2015-06-23 2022-10-28 Intervet Int Bv E vitamint tartalmazó izoxazolin oldat, fertõtlenített ivóvízzel való felhasználásra
WO2018039508A1 (en) * 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
AU2017347886A1 (en) * 2016-10-31 2019-06-20 The Scripps Research Institute Methods and compositions for preventing vector-borne disease transmission
CN111295376B (zh) * 2017-11-07 2024-05-24 英特维特国际股份有限公司 可注射的异噁唑啉药物组合物及其针对寄生虫侵袭的用途
CA3081653A1 (en) * 2017-11-07 2019-05-16 Intervet International B.V. Process for preparing large size isoxazoline particles
KR20250065422A (ko) 2017-12-15 2025-05-12 타르서스 파마수티칼스, 아이엔씨. 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법
CN116034917A (zh) 2017-12-20 2023-05-02 英特维特国际股份有限公司 用于水产养殖中的鱼外部寄生虫监测的方法和系统
WO2019121887A1 (en) * 2017-12-20 2019-06-27 Intervet International B.V. System for external fish parasite monitoring in aquaculture
CN111511201A (zh) * 2017-12-20 2020-08-07 英特维特国际股份有限公司 用于水产养殖中的鱼外部寄生虫监测的系统
EP3726970A1 (en) * 2017-12-20 2020-10-28 Intervet International B.V. System for external fish parasite monitoring in aquaculture
EP3726973A1 (en) * 2017-12-20 2020-10-28 Intervet International B.V. Method and system for external fish parasite monitoring in aquaculture
KR102142916B1 (ko) * 2018-08-17 2020-08-10 부산대학교 산학협력단 상향식 방법을 통한 난용성 약물을 포함하는 나노현탁액의 제조방법 및 이로 제조된 나노현탁액
IL289109B2 (en) * 2019-06-19 2025-10-01 Tarsus Pharmaceuticals Inc Isoxazoline formulations against parasites and methods for treating blepharitis
US20220249445A1 (en) * 2019-06-19 2022-08-11 Tarsus Pharmaceuticals, Inc. Isoxazoline parasiticide formulations and methods for treating blepharitis
EP4077286A1 (en) 2019-12-18 2022-10-26 Elanco Tiergesundheit AG Isoxazoline derivatives as pesticides
WO2022020585A1 (en) 2020-07-24 2022-01-27 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof
CN114306231B (zh) * 2021-12-29 2023-03-24 天津市中升挑战生物科技有限公司 一种氟雷拉纳杀虫剂及其制备方法和应用
CN117064851A (zh) * 2023-09-20 2023-11-17 中国农业大学 一种异噁唑啉类驱虫药制剂的制备方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3727648A1 (de) 1987-08-19 1989-03-02 Bayer Ag Neue avermectin derivate, verfahren zu ihrer herstellung und ihre verwendung
US6998131B2 (en) * 1996-09-19 2006-02-14 Merial Limited Spot-on formulations for combating parasites
JP4883296B2 (ja) 2004-03-05 2012-02-22 日産化学工業株式会社 イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
WO2007053902A1 (en) 2005-11-10 2007-05-18 Bomac Animal Health Pty Limited Method of treating parasites
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
LT2957284T (lt) 2007-06-27 2018-04-10 E. I. Du Pont De Nemours And Company Kovos su gyvūnų kenkėjais būdas
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
WO2010003923A1 (en) * 2008-07-09 2010-01-14 Basf Se Pestcidal active mixtures comprising isoxazoline compounds i
KR101608456B1 (ko) 2008-07-09 2016-04-01 닛산 가가쿠 고교 가부시키 가이샤 이속사졸린 치환 안식향산 아미드 화합물의 제조 방법
EP2364147A2 (en) * 2008-11-19 2011-09-14 Merial Limited Compositions comprising 1-arylpyrazole alone or in combination with formamidine for the treatment of parasitic infection
CA2747060A1 (en) 2008-12-18 2010-07-15 Novartis Ag Isoxazolines derivatives and their use as pesticide
PT2379537E (pt) 2008-12-19 2012-12-27 Novartis Ag Compostos orgânicos
EP2459569B1 (en) 2009-07-30 2015-07-22 Merial, Inc. Insecticidal 4-amino-thieno[2,3-d]-pyrimidine compounds and methods of their use
US20130203591A1 (en) 2010-06-09 2013-08-08 Syngenta Crop Protection Llc Pesticidal mixtures including isoxazoline derivatives
DK178277B1 (da) 2010-06-18 2015-10-26 Novartis Tiergesundheit Ag Diaryloxazolinforbindelser til bekæmpelse af fiskelus
CN103260621B (zh) * 2010-12-27 2016-08-24 英特维特国际股份有限公司 外用局部异噁唑啉制剂
KR101992589B1 (ko) * 2010-12-27 2019-06-24 인터벳 인터내셔널 비.브이. 글리코푸롤을 포함하는 국소 적용 이속사졸린 제제
US20130324538A1 (en) 2011-02-10 2013-12-05 Noëlle Gauvry Isoxazoline derivatives for controlling invertebrate pests
BR112013023068B8 (pt) 2011-03-10 2022-11-22 Zoetis Llc Derivados de isoxazolina espirocíclica, seu uso e seu processo de preparação, e composições veterinárias
AU2012298448A1 (en) 2011-08-25 2014-03-06 Syngenta Participations Ag Isoxazoline derivatives as insecticidal compounds
WO2013026695A1 (en) 2011-08-25 2013-02-28 Syngenta Participations Ag Isoxazoline derivatives as insecticidal compounds
PH12014500537A1 (en) 2011-09-12 2014-04-21 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
BR112014007847A2 (pt) 2011-10-03 2017-04-18 Syngenta Participations Ag derivados de isoxazolina como compostos inseticidas
WO2013150055A1 (en) 2012-04-04 2013-10-10 Intervet International B.V. Solid oral pharmaceutical compositions for isoxazoline compounds
US10350196B2 (en) 2013-09-30 2019-07-16 Zoetis Services Llc Long-acting spiro-isoxazoline formulations
MX376210B (es) 2013-12-20 2025-03-07 Intervet Int Bv Uso de derivados de isoxazolina para el tratamiento o prevención de infestaciones por artrópodos en aves de corral.
JP6581586B2 (ja) * 2013-12-20 2019-09-25 インターベット インターナショナル ベー. フェー. イソオキサゾリン組成物および動物における寄生虫侵襲の予防または処置におけるその使用

Also Published As

Publication number Publication date
ES3036365T3 (en) 2025-09-18
EP4306168A3 (en) 2024-03-13
US10456358B2 (en) 2019-10-29
US11883530B2 (en) 2024-01-30
US20210353537A1 (en) 2021-11-18
MX2016008118A (es) 2016-09-16
EP3082867B1 (en) 2024-01-17
PT4306168T (pt) 2025-07-24
US20240122849A1 (en) 2024-04-18
JP2016540809A (ja) 2016-12-28
HUE066811T2 (hu) 2024-09-28
CN110327468A (zh) 2019-10-15
US20160317439A1 (en) 2016-11-03
PL4306168T3 (pl) 2025-11-17
RU2019114223A (ru) 2019-06-28
PL3082867T3 (pl) 2024-05-13
EP4306168B1 (en) 2025-06-25
JP6581586B2 (ja) 2019-09-25
CN105813651A (zh) 2016-07-27
EP3082867A1 (en) 2016-10-26
MX373872B (es) 2020-03-26
US20200000720A1 (en) 2020-01-02
EP4306168A2 (en) 2024-01-17
RU2016129474A (ru) 2018-01-25
CN105813651B (zh) 2021-11-23
RU2688919C1 (ru) 2019-05-23
CN110327468B (zh) 2023-04-28
WO2015091898A1 (en) 2015-06-25

Similar Documents

Publication Publication Date Title
ES2971061T3 (es) Composiciones de isoxazolina y uso de las mismas en la prevención o el tratamiento de infestaciones parasitarias en animales
US11878006B2 (en) Isoxazoline solution containing vitamin E for use with sanitized drinking water
US12128032B2 (en) Use of isoxazoline derivatives for the treatment or prevention of arthropod infestations in poultry
RU2791637C2 (ru) Изоксазолиновые композиции и их применение в профилактике или лечении паразитарных инвазий животных
RU2796536C9 (ru) Применение изоксазолиновых соединений на домашней птице
RU2796536C2 (ru) Применение изоксазолиновых соединений на домашней птице
US20240366572A1 (en) Isoxazoline complexes and compositions thereof