MX371158B - Compuestos inhibidores de pde2. - Google Patents
Compuestos inhibidores de pde2.Info
- Publication number
- MX371158B MX371158B MX2017007380A MX2017007380A MX371158B MX 371158 B MX371158 B MX 371158B MX 2017007380 A MX2017007380 A MX 2017007380A MX 2017007380 A MX2017007380 A MX 2017007380A MX 371158 B MX371158 B MX 371158B
- Authority
- MX
- Mexico
- Prior art keywords
- organic compounds
- pharmaceuticals
- formula
- pharmaceutical compositions
- relates
- Prior art date
Links
- 150000002894 organic compounds Chemical class 0.000 title 1
- 101100135859 Dictyostelium discoideum regA gene Proteins 0.000 abstract 1
- 101100082606 Plasmodium falciparum (isolate 3D7) PDEbeta gene Proteins 0.000 abstract 1
- 101100135860 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) PDE2 gene Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462088541P | 2014-12-06 | 2014-12-06 | |
| PCT/US2015/064324 WO2016090380A1 (en) | 2014-12-06 | 2015-12-07 | Organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017007380A MX2017007380A (es) | 2017-10-20 |
| MX371158B true MX371158B (es) | 2020-01-20 |
Family
ID=56092607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017007380A MX371158B (es) | 2014-12-06 | 2015-12-07 | Compuestos inhibidores de pde2. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10300064B2 (enExample) |
| EP (1) | EP3226870B1 (enExample) |
| JP (1) | JP6608934B2 (enExample) |
| KR (1) | KR102557603B1 (enExample) |
| CN (1) | CN107205999B (enExample) |
| AU (1) | AU2015357496B2 (enExample) |
| BR (1) | BR112017012007B1 (enExample) |
| CA (1) | CA2969594A1 (enExample) |
| HK (1) | HK1243936A1 (enExample) |
| IL (1) | IL252579B (enExample) |
| MX (1) | MX371158B (enExample) |
| RU (1) | RU2709786C2 (enExample) |
| WO (1) | WO2016090380A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11291666B2 (en) | 2016-09-12 | 2022-04-05 | Intra-Cellular Therapies, Inc. | Uses |
| JP7349450B2 (ja) | 2018-04-25 | 2023-09-22 | バイエル・アクチエンゲゼルシヤフト | 殺有害生物剤としての新規ヘテロアリール－トリアゾール化合物及びヘテロアリール－テトラゾール化合物 |
| US12180210B2 (en) | 2018-10-23 | 2024-12-31 | Intra-Cellular Therapies, Inc. | Compounds |
| US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
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| DK0379917T3 (da) | 1989-01-26 | 1995-12-11 | Bayer Ag | Optisk aktive (meth)acrylsyre-drivater, deres fremstilling, deres polymerisation til optisk aktive polymere og disses anvendelse |
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| EP0686157A1 (en) | 1993-02-26 | 1995-12-13 | Schering Corporation | 2-benzyl-polycyclic guanine derivatives and process for preparing them |
| DE19541264A1 (de) | 1995-11-06 | 1997-05-07 | Bayer Ag | Purin-6-on-derivate |
| US5824683A (en) | 1995-11-28 | 1998-10-20 | Schering Corporation | 2'- 4'-halo- 1,1'-biphenyl!-4-yl!methyl!-5'-methyl-spiro cyclopentane-1,7' (8'H)- 3H! imidazo 2,1-b!purin!-4' (5'H)-ones |
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-
2015
- 2015-12-07 BR BR112017012007-0A patent/BR112017012007B1/pt not_active IP Right Cessation
- 2015-12-07 AU AU2015357496A patent/AU2015357496B2/en not_active Ceased
- 2015-12-07 CN CN201580073695.9A patent/CN107205999B/zh not_active Expired - Fee Related
- 2015-12-07 CA CA2969594A patent/CA2969594A1/en active Pending
- 2015-12-07 EP EP15865341.0A patent/EP3226870B1/en active Active
- 2015-12-07 US US15/533,527 patent/US10300064B2/en active Active
- 2015-12-07 KR KR1020177018721A patent/KR102557603B1/ko active Active
- 2015-12-07 JP JP2017530036A patent/JP6608934B2/ja not_active Expired - Fee Related
- 2015-12-07 HK HK18103471.2A patent/HK1243936A1/zh unknown
- 2015-12-07 MX MX2017007380A patent/MX371158B/es active IP Right Grant
- 2015-12-07 RU RU2017123686A patent/RU2709786C2/ru active
- 2015-12-07 WO PCT/US2015/064324 patent/WO2016090380A1/en not_active Ceased
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2017
- 2017-05-29 IL IL252579A patent/IL252579B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017536410A (ja) | 2017-12-07 |
| IL252579A0 (en) | 2017-07-31 |
| HK1243936A1 (zh) | 2018-07-27 |
| AU2015357496B2 (en) | 2019-09-19 |
| AU2015357496A1 (en) | 2017-07-27 |
| CN107205999B (zh) | 2021-08-03 |
| EP3226870B1 (en) | 2019-09-25 |
| BR112017012007B1 (pt) | 2022-11-01 |
| IL252579B (en) | 2021-05-31 |
| RU2709786C2 (ru) | 2019-12-20 |
| JP6608934B2 (ja) | 2019-11-20 |
| WO2016090380A1 (en) | 2016-06-09 |
| EP3226870A1 (en) | 2017-10-11 |
| US20170360792A1 (en) | 2017-12-21 |
| HK1243933A1 (zh) | 2018-07-27 |
| RU2017123686A (ru) | 2019-01-09 |
| KR20170089000A (ko) | 2017-08-02 |
| US10300064B2 (en) | 2019-05-28 |
| MX2017007380A (es) | 2017-10-20 |
| CA2969594A1 (en) | 2016-06-09 |
| BR112017012007A2 (pt) | 2017-12-26 |
| CN107205999A (zh) | 2017-09-26 |
| RU2017123686A3 (enExample) | 2019-07-17 |
| KR102557603B1 (ko) | 2023-07-19 |
| EP3226870A4 (en) | 2018-05-30 |
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