MX368061B - Proceso de radioetiquetado. - Google Patents

Proceso de radioetiquetado.

Info

Publication number
MX368061B
MX368061B MX2015013801A MX2015013801A MX368061B MX 368061 B MX368061 B MX 368061B MX 2015013801 A MX2015013801 A MX 2015013801A MX 2015013801 A MX2015013801 A MX 2015013801A MX 368061 B MX368061 B MX 368061B
Authority
MX
Mexico
Prior art keywords
composition
facbc
radiolabelling process
radiolabelling
amino
Prior art date
Application number
MX2015013801A
Other languages
English (en)
Spanish (es)
Other versions
MX2015013801A (es
Inventor
Wickstrom Torild
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of MX2015013801A publication Critical patent/MX2015013801A/es
Publication of MX368061B publication Critical patent/MX368061B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C07C227/20—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino-acids or derivatives thereof, e.g. hydrolysis of carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/15—Saturated compounds containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MX2015013801A 2013-03-28 2014-03-28 Proceso de radioetiquetado. MX368061B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1305687.4A GB201305687D0 (en) 2013-03-28 2013-03-28 Radiolabelling process
PCT/EP2014/056344 WO2014154886A1 (en) 2013-03-28 2014-03-28 Radiolabelling process

Publications (2)

Publication Number Publication Date
MX2015013801A MX2015013801A (es) 2016-02-16
MX368061B true MX368061B (es) 2019-09-18

Family

ID=48444922

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015013801A MX368061B (es) 2013-03-28 2014-03-28 Proceso de radioetiquetado.

Country Status (12)

Country Link
US (2) US9999692B2 (en:Method)
EP (1) EP2978456B1 (en:Method)
JP (1) JP6500011B2 (en:Method)
KR (1) KR102218249B1 (en:Method)
CN (1) CN105120905B (en:Method)
AU (1) AU2014242897B2 (en:Method)
CA (1) CA2908029C (en:Method)
ES (1) ES2864702T3 (en:Method)
GB (1) GB201305687D0 (en:Method)
MX (1) MX368061B (en:Method)
RU (1) RU2675371C2 (en:Method)
WO (1) WO2014154886A1 (en:Method)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201305687D0 (en) 2013-03-28 2013-05-15 Ge Healthcare Ltd Radiolabelling process
US20220001034A1 (en) * 2014-06-30 2022-01-06 Ge Healthcare Limited Novel formulation and method of synthesis
GB201621864D0 (en) * 2016-12-21 2017-02-01 Ge Healthcare Ltd Solid phase conditioning

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
WO2006126410A1 (ja) 2005-05-23 2006-11-30 Nihon Medi-Physics Co., Ltd. 新規有機化合物及び該化合物を利用した放射性ハロゲン標識有機化合物の製造方法
AU2006262425C1 (en) * 2005-06-23 2012-06-21 Emory University Stereoselective synthesis of amino acid analogs for tumor imaging
JP2009505947A (ja) 2005-06-23 2009-02-12 エモリー・ユニバーシティ 画像化剤
AU2007251015B2 (en) * 2006-05-11 2011-09-01 Nihon Medi-Physics Co., Ltd. Process for production of radioactive fluorine-labeled organic compound
AU2007335633A1 (en) 2006-12-21 2008-06-26 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic imaging agent
EP2119458B9 (en) * 2007-02-13 2013-08-21 Nihon Medi-Physics Co., Ltd. Method for production of radiation diagnostic imaging agent
RU2476423C2 (ru) 2007-12-19 2013-02-27 Нихон Меди-Физикс Ко., Лтд. Способ получения радиоактивного, меченного фтором органического соединения
SG182378A1 (en) 2009-10-08 2012-08-30 Ge Healthcare Ltd Purification method
EP2658831B1 (en) 2010-12-29 2017-02-15 GE Healthcare Limited Eluent solution
GB2509476B (en) * 2011-12-21 2018-08-08 Ge Healthcare Ltd Ip 18F - Fluciclovine compositions in citrate buffers
GB201305687D0 (en) 2013-03-28 2013-05-15 Ge Healthcare Ltd Radiolabelling process

Also Published As

Publication number Publication date
BR112015024344A2 (pt) 2017-07-18
RU2015138540A (ru) 2017-05-03
AU2014242897B2 (en) 2018-11-08
EP2978456A1 (en) 2016-02-03
US20160051710A1 (en) 2016-02-25
ES2864702T3 (es) 2021-10-14
US20180177900A1 (en) 2018-06-28
CA2908029A1 (en) 2014-10-02
JP2016515564A (ja) 2016-05-30
JP6500011B2 (ja) 2019-04-10
GB201305687D0 (en) 2013-05-15
CA2908029C (en) 2021-05-04
CN105120905A (zh) 2015-12-02
MX2015013801A (es) 2016-02-16
US9999692B2 (en) 2018-06-19
KR102218249B1 (ko) 2021-02-22
RU2015138540A3 (en:Method) 2018-03-01
KR20150136598A (ko) 2015-12-07
CN105120905B (zh) 2021-07-06
AU2014242897A1 (en) 2015-08-27
EP2978456B1 (en) 2021-03-17
WO2014154886A1 (en) 2014-10-02
RU2675371C2 (ru) 2018-12-19

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