MX359550B - Composiciones y metodos para antigenos inmunodominantes de mycobacterium tuberculosis. - Google Patents

Composiciones y metodos para antigenos inmunodominantes de mycobacterium tuberculosis.

Info

Publication number
MX359550B
MX359550B MX2015001830A MX2015001830A MX359550B MX 359550 B MX359550 B MX 359550B MX 2015001830 A MX2015001830 A MX 2015001830A MX 2015001830 A MX2015001830 A MX 2015001830A MX 359550 B MX359550 B MX 359550B
Authority
MX
Mexico
Prior art keywords
methods
compositions
mycobacterium tuberculosis
antigens
immunodominant antigens
Prior art date
Application number
MX2015001830A
Other languages
English (en)
Inventor
Felgner Philip
Laura Gennaro Maria
Original Assignee
Immport Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immport Therapeutics Inc filed Critical Immport Therapeutics Inc
Publication of MX359550B publication Critical patent/MX359550B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a las composiciones, dispositivos y métodos contemplados se relacionan a varios antígenos del patógeno M. tuberculosis y su uso en vacunas, agentes terapéuticos, y varias pruebas de diagnóstico. En aspectos particularmente preferidos, los antígenos son inmunodominantes y tienen reactividades cuantificadas y relativas conocidas con respecto a sueros de una población infectada con el patógeno, y/o tienen una asociación conocida con un parámetro de enfermedad.
MX2015001830A 2009-05-13 2009-05-13 Composiciones y metodos para antigenos inmunodominantes de mycobacterium tuberculosis. MX359550B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2009/043822 WO2010132054A1 (en) 2009-05-13 2009-05-13 Compositions and methods for immunodominant antigens of mycobacterium tuberculosis

Publications (1)

Publication Number Publication Date
MX359550B true MX359550B (es) 2018-10-02

Family

ID=41046910

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011012120A MX344052B (es) 2009-05-13 2009-05-13 Composiciones y metodos para antigenos inmunodominantes de mycobacterium tuberculosis.
MX2015001830A MX359550B (es) 2009-05-13 2009-05-13 Composiciones y metodos para antigenos inmunodominantes de mycobacterium tuberculosis.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2011012120A MX344052B (es) 2009-05-13 2009-05-13 Composiciones y metodos para antigenos inmunodominantes de mycobacterium tuberculosis.

Country Status (4)

Country Link
EP (1) EP2429575A1 (es)
CN (1) CN102573896B (es)
MX (2) MX344052B (es)
WO (1) WO2010132054A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20100411A1 (it) * 2010-07-23 2012-01-24 Massimo Amicosante Uso di sequenze amminoacidiche da mycobacterium tuberculosis o dei loro corrispondenti acidi nucleici per la diagnosi e la prevenzione di infezione tubercolare, relativo kit diagnostico e vaccino.
CN102899334B (zh) * 2012-10-29 2015-02-25 英诺特（唐山）生物技术有限公司 一种结核分枝杆菌重组蛋白质及其制备方法
CN104419710B (zh) * 2013-09-04 2017-06-16 上海市肺科医院 一种结核分枝杆菌的耐药新基因及其应用
CN103525829B (zh) * 2013-09-16 2016-01-06 南京大学（苏州）高新技术研究院 一种可用于结核感染诊断的结核分枝杆菌重组抗原的制备
CN104805063A (zh) * 2014-01-24 2015-07-29 中国人民解放军第三〇九医院 结核分枝杆菌潜伏感染相关蛋白及其制备和应用
EP3578668B1 (en) 2014-07-24 2020-12-30 Abbott Molecular Inc. Methods for the detection and analysis of mycobacterium tuberculosis
ES2897933T3 (es) * 2014-08-15 2022-03-03 Oxford Immunotec Ltd Proteínas de Mycobacterium tuberculosis
AU2015339452B2 (en) 2014-10-28 2021-01-28 Wisconsin Alumni Research Foundation Biomarkers for early diagnosis and differentiation of mycobacterial infection
WO2017011565A1 (en) 2015-07-14 2017-01-19 Abbott Molecular Inc. Compositions and methods for identifying drug resistant tuberculosis
CN105037561B (zh) * 2015-08-24 2018-07-24 华中科技大学 一种融合蛋白cmfo及其应用
CN105483214A (zh) * 2015-11-24 2016-04-13 北京博瑞立安生物技术有限公司 一种结核分枝杆菌检测试剂盒及其应用
CN105572352B (zh) * 2016-02-17 2017-07-28 遵义医学院附属医院 一组结核潜伏感染诊断标志物及其用途
CN105675863B (zh) * 2016-02-17 2017-10-20 遵义医学院附属医院 一组耐多药结核病诊断标志物及其用途
GB201700555D0 (en) 2017-01-12 2017-03-01 Peptinnovate Ltd Method for the treatment of a relapsing-remitting condition
CN110475863B (zh) * 2017-01-19 2023-10-13 株式会社钟化 用于检测堪萨斯分枝杆菌的引物组、探针、试剂盒及方法
CN108096571B (zh) * 2017-12-27 2021-08-17 河南科技大学 一种用于防治结核病的结核多肽疫苗及其制备方法、应用
WO2020051070A1 (en) * 2018-09-07 2020-03-12 Wisconsin Alumni Research Foundation Biomarkers for early diagnosis and differentiation of mycobacterial infection
CN111948399A (zh) * 2019-05-16 2020-11-17 广东体必康生物科技有限公司 结核分枝杆菌抗原蛋白Rv1705c及其T细胞表位肽的应用
CN110240636A (zh) * 2019-06-04 2019-09-17 华中农业大学 牛分枝杆菌分子伴侣蛋白GroEL1及其编码基因与应用
CN113278633B (zh) * 2020-02-20 2022-10-28 北京蛋白质组研究中心 结核分枝杆菌H37Rv基因及编码蛋白和其应用
CN113549604A (zh) * 2020-04-23 2021-10-26 中国医学科学院病原生物学研究所 结核分枝杆菌毒素抗毒素系统Rv1045-Rv1044及其在制备抗结核药物中的应用
CN112457410B (zh) * 2020-11-05 2023-04-07 迈克生物股份有限公司 用于结核分枝杆菌感染检测的抗原组合物
CN112481402B (zh) * 2020-12-29 2024-03-22 上海国际旅行卫生保健中心(上海海关口岸门诊部) 一种基于Sanger测序的结核分枝杆菌MLST分型检测用引物组及其应用
CN114099659A (zh) * 2022-01-29 2022-03-01 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌Rv0934抗原蛋白、其抗原表位肽及其应用
CN114989312B (zh) * 2022-06-27 2023-07-21 安徽理工大学 一种结核分枝杆菌融合蛋白dr2及其应用
CN116120411B (zh) * 2022-12-07 2024-04-12 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌蛋白抗原混合物、多抗原融合蛋白及编码基因和应用
CN116063418B (zh) * 2022-12-08 2024-04-12 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌抗原组合物epdpa015及其制备方法与应用
CN117186247A (zh) * 2023-11-07 2023-12-08 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌多抗原融合蛋白及编码基因和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294328B1 (en) * 1998-06-24 2001-09-25 The Institute For Genomic Research DNA sequences for strain analysis in Mycobacterium tuberculosis
US6892139B2 (en) * 1999-01-29 2005-05-10 The Regents Of The University Of California Determining the functions and interactions of proteins by comparative analysis
GB0500102D0 (en) * 2005-01-05 2005-02-09 Isis Innovation Method for generating a memory t cell response
EP2368568A1 (en) * 2006-11-01 2011-09-28 Immport Therapeutics, INC. Compositions and methods for immunodominant antigens
GB0716070D0 (en) * 2007-08-17 2007-09-26 Fusion Antibodies Ltd Diagnostic method and kit

Also Published As

Publication number Publication date
EP2429575A1 (en) 2012-03-21
CN102573896A (zh) 2012-07-11
CN102573896B (zh) 2016-05-11
MX344052B (es) 2016-12-02
WO2010132054A1 (en) 2010-11-18
MX2011012120A (es) 2012-04-30

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