MX357293B - Anticuerpos anti-cd26 y usos de los mismos. - Google Patents

Anticuerpos anti-cd26 y usos de los mismos.

Info

Publication number
MX357293B
MX357293B MX2014014935A MX2014014935A MX357293B MX 357293 B MX357293 B MX 357293B MX 2014014935 A MX2014014935 A MX 2014014935A MX 2014014935 A MX2014014935 A MX 2014014935A MX 357293 B MX357293 B MX 357293B
Authority
MX
Mexico
Prior art keywords
present
provides
well
treating
antibodies
Prior art date
Application number
MX2014014935A
Other languages
English (en)
Other versions
MX2014014935A (es
Inventor
Francesco Di Naro Antonio
Original Assignee
Adienne S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48092884&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX357293(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adienne S A filed Critical Adienne S A
Publication of MX2014014935A publication Critical patent/MX2014014935A/es
Publication of MX357293B publication Critical patent/MX357293B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)

Abstract

La presente invención se refiere a anticuerpos novedosos capaces de unirse a CD26, así como su uso como un medicamento. Además, la presente invención proporciona anticuerpos para uso en el tratamiento y/o prevención de rechazo inverso (GvHD) para uso en el tratamiento de anemia aplásica y/o para uso en promover el injertado después de transplante de blastocitos hematopoyéticos. Además, la presente invención proporciona composiciones farmacéuticas que comprenden por lo menos un anticuerpo de la presente invención así como proporcionar un kit de partes.
MX2014014935A 2013-02-19 2014-02-19 Anticuerpos anti-cd26 y usos de los mismos. MX357293B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13425029.9A EP2767549A1 (en) 2013-02-19 2013-02-19 Anti-CD26 antibodies and uses thereof
PCT/EP2014/053243 WO2014128168A1 (en) 2013-02-19 2014-02-19 Anti-cd26 antibodies and uses thereof

Publications (2)

Publication Number Publication Date
MX2014014935A MX2014014935A (es) 2015-06-17
MX357293B true MX357293B (es) 2018-07-04

Family

ID=48092884

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014935A MX357293B (es) 2013-02-19 2014-02-19 Anticuerpos anti-cd26 y usos de los mismos.

Country Status (26)

Country Link
US (2) US9376498B2 (es)
EP (3) EP2767549A1 (es)
JP (2) JP6240195B2 (es)
KR (1) KR101869589B1 (es)
CN (1) CN104684931B (es)
AU (1) AU2014220777B2 (es)
CA (1) CA2874422C (es)
CY (1) CY1121980T1 (es)
DK (1) DK2864359T3 (es)
ES (1) ES2738283T3 (es)
HR (1) HRP20191277T8 (es)
HU (1) HUE045150T2 (es)
IL (1) IL237244B (es)
LT (1) LT2864359T (es)
ME (1) ME03753B (es)
MX (1) MX357293B (es)
NZ (1) NZ631111A (es)
PL (1) PL2864359T3 (es)
PT (1) PT2864359T (es)
RS (1) RS59093B1 (es)
RU (1) RU2662933C2 (es)
SA (1) SA515360248B1 (es)
SI (1) SI2864359T1 (es)
SM (1) SMT201900408T1 (es)
TR (1) TR201910572T4 (es)
WO (1) WO2014128168A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11242399B2 (en) 2013-02-19 2022-02-08 Adienne S.A. Anti-CD26 antibodies
EP2767549A1 (en) * 2013-02-19 2014-08-20 Adienne S.A. Anti-CD26 antibodies and uses thereof
US10226465B2 (en) * 2015-01-27 2019-03-12 Scipharm Sàrl Composition for use in increasing engraftment efficacy of haematopoetic stem cells after transplantation
US10630229B2 (en) * 2016-10-11 2020-04-21 Kevin Stapleton Panel mounting bracket with grounding mid-clamp and related methods
KR101960414B1 (ko) * 2016-11-11 2019-03-27 대한민국 사람 유래 dpp-4 유전자를 이용한 당뇨 질환 모델용 형질전환돼지 및 이의 용도
HRP20251577T1 (hr) 2017-12-22 2026-02-27 Adienne S.A. Kvantitativna stanična metoda za određivanje biološke aktivnosti anti-cd26 liganda
CN109709337B (zh) * 2018-12-28 2021-09-14 江苏众红生物工程创药研究院有限公司 人cd26的免疫组化检测试剂盒及其临床应用
US20230295328A1 (en) * 2020-07-28 2023-09-21 Adienne S.A. Treatment of idiopathic inflammatory myopathies
KR20240007229A (ko) * 2021-05-13 2024-01-16 아디에네 에스.에이. 이식편 대 숙주 질환을 치료하는 방법
US20250340665A1 (en) 2021-05-13 2025-11-06 Adienne S.A. Methods of treating dermatomyositis
CN116023491A (zh) * 2021-10-25 2023-04-28 江苏众红生物工程创药研究院有限公司 抗cd26抗体及其应用
CN118359716A (zh) * 2023-01-18 2024-07-19 江苏众红生物工程创药研究院有限公司 抗cd26抗体及其用途

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US4036945A (en) 1976-05-03 1977-07-19 The Massachusetts General Hospital Composition and method for determining the size and location of myocardial infarcts
US4331647A (en) 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4704692A (en) 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5567610A (en) 1986-09-04 1996-10-22 Bioinvent International Ab Method of producing human monoclonal antibodies and kit therefor
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5229275A (en) 1990-04-26 1993-07-20 Akzo N.V. In-vitro method for producing antigen-specific human monoclonal antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ATE207080T1 (de) 1991-11-25 2001-11-15 Enzon Inc Multivalente antigen-bindende proteine
NL9400309A (nl) * 1993-11-04 1995-06-01 Eurogenetics Nv Ligande die in staat is te binden aan de adenosine deaminase bindingsplaats van CD26.
EP1241179B1 (en) 1998-04-15 2006-08-02 Genentech, Inc. Human protein having in vitro antiproliferative activity
EP1197755A1 (en) 2000-10-11 2002-04-17 Pepscan Systems B.V. Identification of protein binding sites
KR100863624B1 (ko) * 2001-05-11 2008-10-15 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 Ｃｄ26을 발현하는 세포와 연관된 질환의 치료제로사용되는 항-ｃｄ26 단클론항체
WO2006078161A1 (en) 2005-01-24 2006-07-27 Pepscan Systems B.V. Binding compounds, immunogenic compounds and peptidomimetics
ES2665422T3 (es) 2005-03-03 2018-04-25 Immunomedics Inc. Anticuerpos L243 humanizados
EP1907425B1 (en) * 2005-07-22 2014-01-08 Y's Therapeutics Co., Ltd. Anti-cd26 antibodies and methods of use thereof
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EP2767549A1 (en) * 2013-02-19 2014-08-20 Adienne S.A. Anti-CD26 antibodies and uses thereof

Also Published As

Publication number Publication date
SMT201900408T1 (it) 2019-09-09
CA2874422C (en) 2021-10-19
MX2014014935A (es) 2015-06-17
US20160264676A1 (en) 2016-09-15
RU2662933C2 (ru) 2018-07-31
RS59093B1 (sr) 2019-09-30
JP2015529204A (ja) 2015-10-05
AU2014220777B2 (en) 2017-03-16
EP2864359B1 (en) 2019-04-24
KR20150023419A (ko) 2015-03-05
RU2014153440A (ru) 2016-07-20
EP2767549A1 (en) 2014-08-20
HRP20191277T1 (hr) 2019-10-18
EP2864359A1 (en) 2015-04-29
ES2738283T3 (es) 2020-01-21
PL2864359T3 (pl) 2019-11-29
ME03753B (me) 2021-04-20
WO2014128168A1 (en) 2014-08-28
AU2014220777A1 (en) 2014-11-27
CN104684931A (zh) 2015-06-03
SA515360248B1 (ar) 2017-02-20
JP2017221205A (ja) 2017-12-21
NZ631111A (en) 2017-06-30
CA2874422A1 (en) 2014-08-28
KR101869589B1 (ko) 2018-06-20
TR201910572T4 (tr) 2019-08-21
US9376498B2 (en) 2016-06-28
IL237244B (en) 2019-09-26
BR112015002130A2 (pt) 2017-11-07
US10208126B2 (en) 2019-02-19
IL237244A0 (en) 2015-04-30
CN104684931B (zh) 2019-08-27
JP6240195B2 (ja) 2017-11-29
DK2864359T3 (da) 2019-07-22
SI2864359T1 (sl) 2019-09-30
CY1121980T1 (el) 2020-10-14
HRP20191277T8 (hr) 2019-11-01
US20150017178A1 (en) 2015-01-15
HUE045150T2 (hu) 2019-12-30
LT2864359T (lt) 2019-09-25
HK1205151A1 (en) 2015-12-11
EP3536711A1 (en) 2019-09-11
PT2864359T (pt) 2019-07-26

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