MX354649B - Compuestos organicos ferricos grado farmaceutico, uso de los mismos y metodos para elaborar los mismos. - Google Patents
Compuestos organicos ferricos grado farmaceutico, uso de los mismos y metodos para elaborar los mismos.Info
- Publication number
- MX354649B MX354649B MX2011008331A MX2011008331A MX354649B MX 354649 B MX354649 B MX 354649B MX 2011008331 A MX2011008331 A MX 2011008331A MX 2011008331 A MX2011008331 A MX 2011008331A MX 354649 B MX354649 B MX 354649B
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical
- organic compounds
- grade ferric
- ferric organic
- methods
- Prior art date
Links
- 150000002894 organic compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 229960002413 ferric citrate Drugs 0.000 abstract 2
- NPFOYSMITVOQOS-UHFFFAOYSA-K iron(III) citrate Chemical compound [Fe+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NPFOYSMITVOQOS-UHFFFAOYSA-K 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- -1 ferric citrate Chemical class 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 238000003908 quality control method Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención describe compuestos férricos orgánicos grado farmacéutico, que incluyen citrato férrico, los cuales son solubles sobre una escala de pH más amplia, y los cuales tienen una gran área de superficie activa; también se describe un procedimiento de control de calidad y fabricación para elaborar un citrato férrico grado farmacéutico que cumpla de manera consistente con la Especificación de Liberación de Fabricación; los compuestos férricos orgánicos grado farmacéutico son adecuados para tratar trastornos caracterizados por niveles elevados de fosfato en suero.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/206,981 US7767851B2 (en) | 2003-02-19 | 2005-08-18 | Ferric organic compounds, uses thereof and methods of making same |
US70951105P | 2005-08-19 | 2005-08-19 | |
PCT/US2006/032385 WO2007022435A2 (en) | 2005-08-18 | 2006-08-18 | Pharmaceutical-grade ferric organic compounds, uses thereof and methods of making same |
Publications (1)
Publication Number | Publication Date |
---|---|
MX354649B true MX354649B (es) | 2018-03-14 |
Family
ID=48087784
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008002360A MX2008002360A (es) | 2005-08-18 | 2006-08-18 | Compuestos organicos ferricos grado farmaceutico, uso de los mismos y metodos para elaborar los mismos. |
MX2011008331A MX354649B (es) | 2005-08-18 | 2006-08-18 | Compuestos organicos ferricos grado farmaceutico, uso de los mismos y metodos para elaborar los mismos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008002360A MX2008002360A (es) | 2005-08-18 | 2006-08-18 | Compuestos organicos ferricos grado farmaceutico, uso de los mismos y metodos para elaborar los mismos. |
Country Status (16)
Country | Link |
---|---|
EP (2) | EP1931689B1 (es) |
JP (2) | JP5667343B2 (es) |
KR (1) | KR20080037083A (es) |
CN (1) | CN101253186A (es) |
AU (1) | AU2006279333C1 (es) |
CA (2) | CA2619591C (es) |
DK (1) | DK1931689T3 (es) |
EA (1) | EA018245B1 (es) |
ES (1) | ES2539635T3 (es) |
HU (1) | HUE025264T2 (es) |
IL (2) | IL189583A (es) |
MX (2) | MX2008002360A (es) |
MY (1) | MY162727A (es) |
NZ (1) | NZ566743A (es) |
TW (1) | TWI375555B (es) |
WO (1) | WO2007022435A2 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI335218B (en) | 2003-02-19 | 2011-01-01 | Panion & Bf Biotech Inc | Ferric organic compounds, uses thereof and methods of making same |
US8093423B2 (en) | 2003-02-19 | 2012-01-10 | Globoasia, Llc | Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same |
WO2007089571A2 (en) * | 2006-01-30 | 2007-08-09 | Globoasia, Llc | Method of treating chronic kidney disease |
US7985429B2 (en) | 2006-03-03 | 2011-07-26 | C. B. Fleet Company, Inc. | Flavored colonic cleansing system |
US7998510B2 (en) | 2006-08-17 | 2011-08-16 | C. B. Fleet Company, Inc. | Low dose colonic cleansing system |
WO2008058438A1 (fr) * | 2006-11-17 | 2008-05-22 | Jung-Ren Su | Utilisation de citrate ferrique dans la préparation de médicaments servant à traiter la calcification des vaisseaux sanguins |
WO2009032538A1 (en) * | 2007-08-31 | 2009-03-12 | C.B. Fleet Company, Inc. | Method of preventing nephrocalcinosis |
CN102573807A (zh) | 2009-07-21 | 2012-07-11 | 凯克斯生物制药公司 | 柠檬酸铁剂型 |
JP5167389B2 (ja) * | 2010-07-07 | 2013-03-21 | 日本たばこ産業株式会社 | クエン酸第二鉄を含む錠剤 |
US20120238622A1 (en) * | 2011-01-18 | 2012-09-20 | Japan Tobacco Inc. | Iron (iii) citrate, substantially free of beta-iron hydroxide oxide |
KR101455921B1 (ko) * | 2012-01-30 | 2014-11-12 | 성균관대학교산학협력단 | 수난용성 약물을 내부에 포함하는 알부민 나노입자 제조방법 |
KR102150135B1 (ko) | 2012-06-21 | 2020-08-31 | 케릭스 바이오파마슈티컬스 인코포레이티드 | 만성 신장 질환 환자의 치료에서 시트르산 제2철의 용도 |
EP3653061A1 (en) * | 2012-09-04 | 2020-05-20 | The Board of Regents of the University of Texas System | Citrate-rich calcium-magnesium supplement and uses thereof |
LT3003327T (lt) | 2013-06-05 | 2017-12-27 | Tricida Inc. | Protonus surišantys polimerai, skirti geriamajam vartojimui |
EP3747432A1 (en) * | 2013-11-04 | 2020-12-09 | Keryx Biopharmaceuticals, Inc. | Ferric citrate for reducing cardiac failure in chronic kidney disease patients |
ES2857177T3 (es) | 2014-12-10 | 2021-09-28 | Tricida Inc | Polímeros de unión de protones para administración oral |
CN107108443A (zh) * | 2014-12-17 | 2017-08-29 | 拜欧弗印度制药有限公司 | 合成铁有机化合物的改进方法 |
JP6206420B2 (ja) * | 2015-01-13 | 2017-10-04 | テクノサイエンス株式会社 | クエン酸第二鉄を高濃度で含有するゲル状組成物の製造方法 |
EP3265077A4 (en) * | 2015-03-04 | 2018-10-24 | Keryx Biopharmaceuticals, Inc. | Use of ferric citrate in the treatment of iron-deficiency anemia |
WO2016162888A1 (en) * | 2015-04-09 | 2016-10-13 | Actavis Group Ptc Ehf. | Process for preparing pharmaceutical grade ferric citrate |
US20190209607A1 (en) | 2016-05-06 | 2019-07-11 | Tricida, Inc. | Compositions for treating acid-base disorders |
US10934380B1 (en) | 2017-09-25 | 2021-03-02 | Tricida, Inc. | Crosslinked poly(allylamine) polymer pharmaceutical compositions |
US11266684B2 (en) | 2017-11-03 | 2022-03-08 | Tricida, Inc. | Compositions for and method of treating acid-base disorders |
CN108863771A (zh) * | 2018-05-24 | 2018-11-23 | 国药集团化学试剂有限公司 | 一种柠檬酸铁结晶的制备方法 |
JP7175235B2 (ja) * | 2019-04-19 | 2022-11-18 | 株式会社トクヤマ | クエン酸第二鉄水和物の製造方法 |
CN110105194A (zh) * | 2019-05-10 | 2019-08-09 | 上海万巷制药有限公司 | 一种药用级柠檬酸铁的制备方法 |
EP4347022A1 (en) | 2021-05-27 | 2024-04-10 | Keryx Biopharmaceuticals, Inc. | Pediatric formulations of ferric citrate |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5753706A (en) * | 1996-12-16 | 1998-05-19 | Hsu; Chen Hsing | Methods for treating renal failure |
CN1315174A (zh) | 2000-03-31 | 2001-10-03 | 苏荣仁 | 治疗肾衰的药物组合物 |
TWI335218B (en) | 2003-02-19 | 2011-01-01 | Panion & Bf Biotech Inc | Ferric organic compounds, uses thereof and methods of making same |
US6903235B2 (en) * | 2003-10-08 | 2005-06-07 | Panion & Bf Biotech Inc. | Pharmaceutical-grade ferric citrate |
-
2006
- 2006-08-18 MX MX2008002360A patent/MX2008002360A/es active IP Right Grant
- 2006-08-18 TW TW095130373A patent/TWI375555B/zh active
- 2006-08-18 CA CA2619591A patent/CA2619591C/en active Active
- 2006-08-18 EP EP06813544.1A patent/EP1931689B1/en not_active Revoked
- 2006-08-18 EA EA200800593A patent/EA018245B1/ru not_active IP Right Cessation
- 2006-08-18 DK DK06813544.1T patent/DK1931689T3/en active
- 2006-08-18 EP EP20120192822 patent/EP2594551A1/en active Pending
- 2006-08-18 NZ NZ566743A patent/NZ566743A/en not_active IP Right Cessation
- 2006-08-18 KR KR1020087006131A patent/KR20080037083A/ko active Search and Examination
- 2006-08-18 MY MYPI20063971A patent/MY162727A/en unknown
- 2006-08-18 AU AU2006279333A patent/AU2006279333C1/en active Active
- 2006-08-18 WO PCT/US2006/032385 patent/WO2007022435A2/en active Application Filing
- 2006-08-18 JP JP2008527177A patent/JP5667343B2/ja active Active
- 2006-08-18 ES ES06813544.1T patent/ES2539635T3/es active Active
- 2006-08-18 CA CA3050453A patent/CA3050453C/en active Active
- 2006-08-18 MX MX2011008331A patent/MX354649B/es unknown
- 2006-08-18 CN CNA2006800321082A patent/CN101253186A/zh active Pending
- 2006-08-18 HU HUE06813544A patent/HUE025264T2/en unknown
-
2008
- 2008-02-18 IL IL189583A patent/IL189583A/en active IP Right Grant
-
2013
- 2013-05-15 JP JP2013103220A patent/JP2013177416A/ja active Pending
- 2013-10-17 IL IL228952A patent/IL228952B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
AU2006279333C1 (en) | 2012-12-13 |
IL189583A (en) | 2013-10-31 |
MY162727A (en) | 2017-07-14 |
WO2007022435A2 (en) | 2007-02-22 |
MX2008002360A (es) | 2008-04-29 |
ES2539635T3 (es) | 2015-07-02 |
EP1931689A2 (en) | 2008-06-18 |
EA200800593A1 (ru) | 2008-10-30 |
EA018245B1 (ru) | 2013-06-28 |
CA3050453C (en) | 2021-07-27 |
DK1931689T3 (en) | 2015-06-01 |
TWI375555B (en) | 2012-11-01 |
CA3050453A1 (en) | 2007-02-22 |
EP1931689B1 (en) | 2015-02-25 |
CN101253186A (zh) | 2008-08-27 |
WO2007022435A3 (en) | 2007-05-10 |
JP5667343B2 (ja) | 2015-02-12 |
TW200740431A (en) | 2007-11-01 |
AU2006279333B2 (en) | 2012-07-26 |
AU2006279333A1 (en) | 2007-02-22 |
IL228952B (en) | 2018-06-28 |
EP2594551A1 (en) | 2013-05-22 |
HUE025264T2 (en) | 2016-02-29 |
JP2013177416A (ja) | 2013-09-09 |
CA2619591A1 (en) | 2007-02-22 |
IL189583A0 (en) | 2008-08-07 |
JP2009504777A (ja) | 2009-02-05 |
IL228952A0 (en) | 2013-12-31 |
EP1931689A4 (en) | 2011-02-09 |
CA2619591C (en) | 2020-03-24 |
NZ566743A (en) | 2010-07-30 |
KR20080037083A (ko) | 2008-04-29 |
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