MX349752B - Proceso para la preparacion de 3-metilsulfonilpropionitrilo. - Google Patents

Proceso para la preparacion de 3-metilsulfonilpropionitrilo.

Info

Publication number
MX349752B
MX349752B MX2014010228A MX2014010228A MX349752B MX 349752 B MX349752 B MX 349752B MX 2014010228 A MX2014010228 A MX 2014010228A MX 2014010228 A MX2014010228 A MX 2014010228A MX 349752 B MX349752 B MX 349752B
Authority
MX
Mexico
Prior art keywords
methylsulfonylpropionitrile
preparing
degrees
relates
present
Prior art date
Application number
MX2014010228A
Other languages
English (en)
Other versions
MX2014010228A (es
Inventor
St Laurent Joseph
s jones Gerald
M Breese David
Original Assignee
Olatec Ind Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olatec Ind Llc filed Critical Olatec Ind Llc
Publication of MX2014010228A publication Critical patent/MX2014010228A/es
Publication of MX349752B publication Critical patent/MX349752B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a procedimientos para la preparación de 3-metilsulfonilpropionitrilo. Los procesos proporcionan un buen rendimiento y una buena pureza del producto final y proporcionan una reacción controlable. La presente invención también se refiere a una forma cristalina del 3-metilsulfonilpropionitrilo que tiene picos de difracción de rayos X a 13.9 ± 0.1, 19.2 ± 0.1, 20.0 ± 0.1, 22.5 ± 0.1, 23.2 ± 0.1, 25.7 ± 0.1, 28.1 ± 0.1, 29.9 ± 0.1, y 30.6 ± 0.1 grados 2?, y en donde el pico más intenso es el pico a 13.9 ± 0.1 grados 2?.
MX2014010228A 2012-02-27 2013-02-26 Proceso para la preparacion de 3-metilsulfonilpropionitrilo. MX349752B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261603744P 2012-02-27 2012-02-27
PCT/US2013/027749 WO2013130436A1 (en) 2012-02-27 2013-02-26 Process for preparing 3-methylsulfonylpropionitrile

Publications (2)

Publication Number Publication Date
MX2014010228A MX2014010228A (es) 2015-07-06
MX349752B true MX349752B (es) 2017-08-11

Family

ID=49003587

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014010228A MX349752B (es) 2012-02-27 2013-02-26 Proceso para la preparacion de 3-metilsulfonilpropionitrilo.

Country Status (9)

Country Link
US (3) US8802885B2 (es)
EP (1) EP2819995B1 (es)
JP (1) JP6151723B2 (es)
KR (1) KR102002664B1 (es)
CN (1) CN104185621B (es)
AU (1) AU2013226300B2 (es)
CA (1) CA2864181C (es)
MX (1) MX349752B (es)
WO (1) WO2013130436A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013226300B2 (en) * 2012-02-27 2017-09-28 Olatec Therapeutics Llc Process for preparing 3-methylsulfonylpropionitrile
JP6426746B2 (ja) * 2013-10-07 2018-11-21 オラテック セラピューティクス リミティド ライアビリティ カンパニー ４−メチルスルホニル−２−ブテンニトリル及びその医薬上の使用
US9815781B1 (en) * 2015-02-20 2017-11-14 Olatec Therapeutics Llc Process for preparing 3-(methylsulfonyl)propionitrile
US10273203B2 (en) 2017-04-11 2019-04-30 Olatec Therapeutics Llc Deuterated 3-methanesulfonylpropionitrile

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444175A (en) * 1966-11-09 1969-05-13 Merck & Co Inc Certain picolylmethyl sulfones
EP0008532B1 (en) * 1978-08-22 1983-07-20 Sumitomo Chemical Company, Limited Synthesis of amines
DE3041155A1 (de) 1980-10-31 1982-06-09 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,3-dichlor-sulfonyl-acrylnitrilen
JPS58501722A (ja) 1981-10-16 1983-10-13 アボツト　ラボラトリ−ズ 〔１↓−（２↓−ベンゾオキサゾリル）ヒドラジノ〕アルキルニトリル誘導体
JPS5942359A (ja) * 1982-09-01 1984-03-08 Nippon Tokushu Kagaku Kogyo Kk スルホン類の製造法
US5175192A (en) 1984-03-19 1992-12-29 The Rockefeller University Inhibitors of the advanced glycosylation of proteins and methods of use therefor
EP0355049A3 (en) 1988-08-18 1990-06-13 Zeneca Limited Heterocyclic compounds
US5348838A (en) 1991-07-31 1994-09-20 Kabushiki Kaisha Toshiba Photosensitive composition comprising alkali soluble binder and photoacid generator having sulfonyl group
US6551615B1 (en) 2001-10-18 2003-04-22 M/S. Strides Arcolab Limited Dexibuprofen-containing soft gelatin capsules and process for preparing the same
US7423064B2 (en) 2004-09-24 2008-09-09 Olatec Industries, Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
WO2007074473A1 (en) * 2005-12-27 2007-07-05 Dabur Pharma Limited An improved process for preparation of bicalutamide
EP1979325A1 (en) * 2006-01-11 2008-10-15 AstraZeneca AB Morpholino pyrimidine derivatives and their use in therapy
PT1988779E (pt) 2006-02-16 2015-09-04 Anacor Pharmaceuticals Inc Moléculas pequenas contendo boro como agentes antiinflamatórios
US20100221337A1 (en) 2007-02-14 2010-09-02 Logical Therapeutics, Inc. Method of treating arthritis, pain or inflammation with naproxen 2(methanesulfonyl)ethyl ester and an h2 receptor antagonist
NZ587955A (en) 2008-03-06 2012-10-26 Anacor Pharmaceuticals Inc Boron-containing small molecules as anti-inflammatory agents
WO2010018814A1 (ja) * 2008-08-12 2010-02-18 宇部興産株式会社 非水電解液及びそれを用いたリチウム電池
AU2010226794A1 (en) 2009-03-18 2011-10-27 Olatec Industries Llc Compounds for treating inflammation and pain
CN103260613B (zh) * 2010-12-15 2015-01-14 欧拉泰克工业有限责任公司 用于治疗炎症和疼痛的3-甲磺酰基丙腈
AU2013226300B2 (en) * 2012-02-27 2017-09-28 Olatec Therapeutics Llc Process for preparing 3-methylsulfonylpropionitrile

Also Published As

Publication number Publication date
CA2864181A1 (en) 2013-09-06
EP2819995B1 (en) 2017-02-01
EP2819995A4 (en) 2015-09-02
US20130225865A1 (en) 2013-08-29
MX2014010228A (es) 2015-07-06
JP2015511582A (ja) 2015-04-20
JP6151723B2 (ja) 2017-06-21
US20150232421A1 (en) 2015-08-20
WO2013130436A1 (en) 2013-09-06
KR102002664B1 (ko) 2019-07-23
US9399620B2 (en) 2016-07-26
KR20140129186A (ko) 2014-11-06
US9024056B2 (en) 2015-05-05
AU2013226300A1 (en) 2014-09-25
AU2013226300B2 (en) 2017-09-28
EP2819995A1 (en) 2015-01-07
US8802885B2 (en) 2014-08-12
US20140330037A1 (en) 2014-11-06
CN104185621A (zh) 2014-12-03
CA2864181C (en) 2020-06-02
CN104185621B (zh) 2016-09-07

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