MX349752B - Proceso para la preparacion de 3-metilsulfonilpropionitrilo. - Google Patents

Proceso para la preparacion de 3-metilsulfonilpropionitrilo.

Info

Publication number
MX349752B
MX349752B MX2014010228A MX2014010228A MX349752B MX 349752 B MX349752 B MX 349752B MX 2014010228 A MX2014010228 A MX 2014010228A MX 2014010228 A MX2014010228 A MX 2014010228A MX 349752 B MX349752 B MX 349752B
Authority
MX
Mexico
Prior art keywords
methylsulfonylpropionitrile
preparing
degrees
relates
present
Prior art date
Application number
MX2014010228A
Other languages
English (en)
Other versions
MX2014010228A (es
Inventor
St Laurent Joseph
s jones Gerald
M Breese David
Original Assignee
Olatec Ind Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olatec Ind Llc filed Critical Olatec Ind Llc
Publication of MX2014010228A publication Critical patent/MX2014010228A/es
Publication of MX349752B publication Critical patent/MX349752B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a procedimientos para la preparación de 3-metilsulfonilpropionitrilo. Los procesos proporcionan un buen rendimiento y una buena pureza del producto final y proporcionan una reacción controlable. La presente invención también se refiere a una forma cristalina del 3-metilsulfonilpropionitrilo que tiene picos de difracción de rayos X a 13.9 ± 0.1, 19.2 ± 0.1, 20.0 ± 0.1, 22.5 ± 0.1, 23.2 ± 0.1, 25.7 ± 0.1, 28.1 ± 0.1, 29.9 ± 0.1, y 30.6 ± 0.1 grados 2?, y en donde el pico más intenso es el pico a 13.9 ± 0.1 grados 2?.
MX2014010228A 2012-02-27 2013-02-26 Proceso para la preparacion de 3-metilsulfonilpropionitrilo. MX349752B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261603744P 2012-02-27 2012-02-27
PCT/US2013/027749 WO2013130436A1 (en) 2012-02-27 2013-02-26 Process for preparing 3-methylsulfonylpropionitrile

Publications (2)

Publication Number Publication Date
MX2014010228A MX2014010228A (es) 2015-07-06
MX349752B true MX349752B (es) 2017-08-11

Family

ID=49003587

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014010228A MX349752B (es) 2012-02-27 2013-02-26 Proceso para la preparacion de 3-metilsulfonilpropionitrilo.

Country Status (9)

Country Link
US (3) US8802885B2 (es)
EP (1) EP2819995B1 (es)
JP (1) JP6151723B2 (es)
KR (1) KR102002664B1 (es)
CN (1) CN104185621B (es)
AU (1) AU2013226300B2 (es)
CA (1) CA2864181C (es)
MX (1) MX349752B (es)
WO (1) WO2013130436A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102002664B1 (ko) * 2012-02-27 2019-07-23 오라텍 세라퓨틱스 엘엘씨 3-메틸술포닐프로피오니트릴의 제조 방법
CN105683158A (zh) * 2013-10-07 2016-06-15 欧拉泰克治疗有限责任公司 4-甲基磺酰基-2-丁烯腈及其药学用途
US9815781B1 (en) * 2015-02-20 2017-11-14 Olatec Therapeutics Llc Process for preparing 3-(methylsulfonyl)propionitrile
US10273203B2 (en) 2017-04-11 2019-04-30 Olatec Therapeutics Llc Deuterated 3-methanesulfonylpropionitrile

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444175A (en) * 1966-11-09 1969-05-13 Merck & Co Inc Certain picolylmethyl sulfones
EP0040896B1 (en) * 1978-08-22 1984-04-25 Sumitomo Chemical Company, Limited Synthesis of amides
DE3041155A1 (de) 1980-10-31 1982-06-09 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,3-dichlor-sulfonyl-acrylnitrilen
CH654573A5 (de) 1981-10-16 1986-02-28 Abbott Lab (1-(2-benzoxazolyl-, 2-benzthiazolyl- und 2-indolyl)-hydrazino)-alkannitrilderivate.
JPS5942359A (ja) * 1982-09-01 1984-03-08 Nippon Tokushu Kagaku Kogyo Kk スルホン類の製造法
US5175192A (en) 1984-03-19 1992-12-29 The Rockefeller University Inhibitors of the advanced glycosylation of proteins and methods of use therefor
EP0355049A3 (en) 1988-08-18 1990-06-13 Zeneca Limited Heterocyclic compounds
US5348838A (en) 1991-07-31 1994-09-20 Kabushiki Kaisha Toshiba Photosensitive composition comprising alkali soluble binder and photoacid generator having sulfonyl group
US6551615B1 (en) 2001-10-18 2003-04-22 M/S. Strides Arcolab Limited Dexibuprofen-containing soft gelatin capsules and process for preparing the same
US7423064B2 (en) 2004-09-24 2008-09-09 Olatec Industries, Llc Composition for treating bacterial, viral, fungal diseases, inflammation and pain
WO2007074473A1 (en) * 2005-12-27 2007-07-05 Dabur Pharma Limited An improved process for preparation of bicalutamide
WO2007080382A1 (en) * 2006-01-11 2007-07-19 Astrazeneca Ab Morpholino pyrimidine derivatives and their use in therapy
SI2719388T1 (sl) 2006-02-16 2019-06-28 Anacor Pharmaceuticals, Inc. Majhne molekule, polnjene z borom, kot učinkovine proti vnetjem
WO2008101064A1 (en) 2007-02-14 2008-08-21 Logical Therapeutics, Inc. Method of treating arthritis, pain or inflammation with naproxen 2(methanesulfonyl)ethyl ester and an h2 receptor antagonist
EP3246034A1 (en) 2008-03-06 2017-11-22 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-inflammatory agents
WO2010018814A1 (ja) * 2008-08-12 2010-02-18 宇部興産株式会社 非水電解液及びそれを用いたリチウム電池
EP2408740B1 (en) 2009-03-18 2013-11-20 Olatec Industries LLC Compounds for treating inflammation and pain
US8476316B2 (en) 2010-12-15 2013-07-02 Olatec Industries Llc 3-methanesulfonylpropionitrile for treating inflammation and pain
KR102002664B1 (ko) * 2012-02-27 2019-07-23 오라텍 세라퓨틱스 엘엘씨 3-메틸술포닐프로피오니트릴의 제조 방법

Also Published As

Publication number Publication date
JP6151723B2 (ja) 2017-06-21
CA2864181C (en) 2020-06-02
US9024056B2 (en) 2015-05-05
US20130225865A1 (en) 2013-08-29
JP2015511582A (ja) 2015-04-20
US8802885B2 (en) 2014-08-12
WO2013130436A1 (en) 2013-09-06
CA2864181A1 (en) 2013-09-06
AU2013226300B2 (en) 2017-09-28
CN104185621A (zh) 2014-12-03
EP2819995B1 (en) 2017-02-01
EP2819995A4 (en) 2015-09-02
MX2014010228A (es) 2015-07-06
KR102002664B1 (ko) 2019-07-23
US9399620B2 (en) 2016-07-26
AU2013226300A1 (en) 2014-09-25
KR20140129186A (ko) 2014-11-06
EP2819995A1 (en) 2015-01-07
US20140330037A1 (en) 2014-11-06
US20150232421A1 (en) 2015-08-20
CN104185621B (zh) 2016-09-07

Similar Documents

Publication Publication Date Title
JOP20210065A1 (ar) عملية لتحضير 5- فلورو-1h- بيرازولوبيريدينات مستبدلة
WO2014043706A8 (en) Method of synthesizing thyroid hormone analogs and polymorphs thereof
MY172391A (en) Processes for preparing dihydropyrimidine derivatives and intermediates thereof
WO2012087628A3 (en) Production of polycrystalline silicon by the thermal decomposition of dichlorosilane in a fluidized bed reactor
PH12015500644B1 (en) Novel rig-i ligands and methods for producing them
NZ757222A (en) Crystalline forms of diazabicyclooctane derivative and production process thereof
NZ605234A (en) Process for the synthesis of substituted morphinans
WO2015008218A3 (en) Process for the preparation of suvorexant and intermediates useful in the synthesis of suvorexant
MY156181A (en) Method and system for producing high-purity hydrogen chloride
MX349752B (es) Proceso para la preparacion de 3-metilsulfonilpropionitrilo.
WO2014141092A3 (en) Improved process for the preparation of tenofovir
ZA201500009B (en) Process for the production of crystalline titanium powder
WO2016105172A3 (en) A method for preparing gadobutrol
IN2014DN09053A (es)
NZ603653A (en) Processes for the preparation of dipyridamole
WO2013049314A3 (en) Production of polycrystalline silicon by the thermal decomposition of silane in a fluidized bed reactor
MY176977A (en) Method for preparing cysteine or a derivative thereof using a novel o-phosphoserine sulfhydrylase
WO2014087208A3 (en) A process of preparing alcaftadine
MY160954A (en) Agomelatine intermediates and preparation method thereof
MY165659A (en) Novel method of preparing benzoimidazole derivatives
MY165746A (en) Method for the production of 2-octyl acrylate by means of transesterification
IN2014DN08226A (es)
WO2012115402A3 (en) Crystalline form of docetaxel and process for preparation thereof
WO2016105106A3 (ko) 무수당 알코올의 연속적인 생산방법
WO2014133291A9 (ko) (2rs)-아미노-(3s)-히드록시-부티르산 또는 이의 유도체의 제조방법

Legal Events

Date Code Title Description
FG Grant or registration