MX349587B - Extractos de cynara scolymus para el tratamiento de la dislipidemia. - Google Patents

Extractos de cynara scolymus para el tratamiento de la dislipidemia.

Info

Publication number
MX349587B
MX349587B MX2014003050A MX2014003050A MX349587B MX 349587 B MX349587 B MX 349587B MX 2014003050 A MX2014003050 A MX 2014003050A MX 2014003050 A MX2014003050 A MX 2014003050A MX 349587 B MX349587 B MX 349587B
Authority
MX
Mexico
Prior art keywords
dyslipidaemia
treatment
cynara scolymus
extracts
useful
Prior art date
Application number
MX2014003050A
Other languages
English (en)
Other versions
MX2014003050A (es
Inventor
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44907959&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX349587(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Indena Spa filed Critical Indena Spa
Publication of MX2014003050A publication Critical patent/MX2014003050A/es
Publication of MX349587B publication Critical patent/MX349587B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Furan Compounds (AREA)

Abstract

La presente invención se refiere a la preparación de los extractos de las hojas de Cynara scolymus, que resultan útiles para la prevención y el tratamiento de la dislipidemia, en particular para aumentar el colesterol HDL en pacientes con riesgo cardiovascular; dichos extractos son útiles para normalizar el equilibrio de lípidos y carbohidratos y aumentar significativamente el valor del colesterol HDL mediante el cambio favorable de la proporción LDL/HDL, en especial en pacientes con dislipidemia inducida por medicamentos que sufrieron un infarto.
MX2014003050A 2011-09-16 2012-09-13 Extractos de cynara scolymus para el tratamiento de la dislipidemia. MX349587B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001670A ITMI20111670A1 (it) 2011-09-16 2011-09-16 Estratti di cynara scolimus per il trattamento di dislipidemie
PCT/EP2012/067889 WO2013037857A1 (en) 2011-09-16 2012-09-13 Cynara scolymus extracts for the treatment of dyslipidaemia

Publications (2)

Publication Number Publication Date
MX2014003050A MX2014003050A (es) 2014-04-10
MX349587B true MX349587B (es) 2017-08-03

Family

ID=44907959

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003050A MX349587B (es) 2011-09-16 2012-09-13 Extractos de cynara scolymus para el tratamiento de la dislipidemia.

Country Status (22)

Country Link
US (1) US9687468B2 (es)
EP (1) EP2755669B1 (es)
JP (2) JP2014526486A (es)
KR (1) KR102026993B1 (es)
CN (2) CN103874498A (es)
AR (1) AR087878A1 (es)
AU (1) AU2012307404B2 (es)
BR (1) BR112014004532B1 (es)
CA (1) CA2845708C (es)
CL (1) CL2014000595A1 (es)
ES (1) ES2629186T3 (es)
HK (1) HK1198935A1 (es)
HU (1) HUE035035T2 (es)
IL (1) IL231497B (es)
IT (1) ITMI20111670A1 (es)
MX (1) MX349587B (es)
PL (1) PL2755669T3 (es)
PT (1) PT2755669T (es)
RU (1) RU2608459C2 (es)
SG (1) SG11201400618XA (es)
SI (1) SI2755669T1 (es)
WO (1) WO2013037857A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20121570A1 (it) * 2012-09-20 2014-03-21 Indena Spa Nuovi estratti di cynara scolimus, coffea spp. e olea europaea per il trattamento della sindrome metabolica
FR3042413B1 (fr) * 2015-10-20 2019-07-12 Valbiotis Composition comprenant un melange de molecules extraites de chrysanthellum indicum et de cynara scolymus et utilisation pour agir sur le metabolisme glucidique et/ou lipidique
CN108142881A (zh) * 2018-03-20 2018-06-12 爱可道生物科技有限公司 一种洋蓟花蕾提取物降血压胶囊制品及其生产工艺
WO2021220050A1 (en) * 2020-05-01 2021-11-04 Health And Happiness (H&H) Hong Kong Limited New compositions useful for treating elevated blood lipid levels

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19627376A1 (de) * 1996-07-06 1998-01-08 Aar Pharma Adler Apotheke Verwendung von Artischocken-(Cynara)-Extrakten
EP0958828A1 (de) * 1998-05-22 1999-11-24 Greither, Peter Präparat auf der Basis der Artischockenpflanze, insbesondere zur Verwendung als Arzneimittel oder Nahrungsergänzungsmittel
US6162438A (en) * 1999-06-24 2000-12-19 Chromak Research, Inc. Herbal compositions and their use as agents for control of hypertension, hypercholesterolemia and hyperlipidemia
DE10164893B4 (de) * 2001-08-08 2008-08-28 Divapharma Chur Ag Verfahren zur Herstellung von Artischockenblätterextrakten und so erhaltene Artischockenblätterextrakte
CN100496525C (zh) * 2004-04-02 2009-06-10 李嫦梅 从洋蓟根、茎、叶中提取活性成份的方法及其应用
ITMI20051347A1 (it) * 2005-07-14 2007-01-15 Indena Spa Estratti di cynara scolimus loro uso e formulazioni che li contengono
EP1967199A1 (en) * 2007-03-07 2008-09-10 Indena S.P.A. Cynara scolymus extracts and compositions containing them
BRPI0808569A2 (pt) * 2007-03-07 2014-09-02 Indena Spa Extratos de cynara scolymus e composições contendo a mesma
US20080220096A1 (en) * 2007-03-07 2008-09-11 Indena S. P. A. Cynara scolymus extracts and compositions containing them
WO2009100970A1 (de) * 2008-02-14 2009-08-20 Swiss Caps Rechte Und Lizenzen Ag Darreichungsform enthaltend zubereitungen aus solanum melongena und cynara scolymus
AU2010206327B2 (en) * 2009-01-20 2015-06-04 Indena S.P.A. Compositions comprising a lipophilic extract of Zingiber officinale and an extract of Cynara scolymus, which are useful for the prevention and treatment of oesophageal reflux and irritable bowel syndrome
EP2345646A1 (en) * 2010-01-14 2011-07-20 InterMed Discovery GmbH Use of tricyclic sesquiterpene lactones in the treatment of obesity and related diseases and non-therapeutic treatable conditions

Also Published As

Publication number Publication date
MX2014003050A (es) 2014-04-10
JP2017165783A (ja) 2017-09-21
AR087878A1 (es) 2014-04-23
HUE035035T2 (en) 2018-05-02
EP2755669A1 (en) 2014-07-23
RU2014109450A (ru) 2015-10-27
CN103874498A (zh) 2014-06-18
JP2014526486A (ja) 2014-10-06
JP6335373B2 (ja) 2018-05-30
ES2629186T3 (es) 2017-08-07
CL2014000595A1 (es) 2014-11-14
RU2608459C2 (ru) 2017-01-18
PT2755669T (pt) 2017-06-30
CA2845708A1 (en) 2013-03-21
CA2845708C (en) 2019-11-12
KR20140067044A (ko) 2014-06-03
AU2012307404A1 (en) 2014-03-06
CN111184754A (zh) 2020-05-22
IL231497A0 (en) 2014-04-30
SG11201400618XA (en) 2014-05-29
BR112014004532B1 (pt) 2022-02-22
WO2013037857A1 (en) 2013-03-21
EP2755669B1 (en) 2017-04-05
HK1198935A1 (en) 2015-06-19
KR102026993B1 (ko) 2019-09-30
IL231497B (en) 2019-07-31
US20140228428A1 (en) 2014-08-14
US9687468B2 (en) 2017-06-27
BR112014004532A2 (pt) 2017-03-28
SI2755669T1 (sl) 2017-06-30
PL2755669T3 (pl) 2017-09-29
AU2012307404B2 (en) 2017-05-25
ITMI20111670A1 (it) 2013-03-17

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