MX348821B - Polímeros de amina para usarse como secuestrantes del ácido biliar. - Google Patents
Polímeros de amina para usarse como secuestrantes del ácido biliar.Info
- Publication number
- MX348821B MX348821B MX2012009783A MX2012009783A MX348821B MX 348821 B MX348821 B MX 348821B MX 2012009783 A MX2012009783 A MX 2012009783A MX 2012009783 A MX2012009783 A MX 2012009783A MX 348821 B MX348821 B MX 348821B
- Authority
- MX
- Mexico
- Prior art keywords
- bile acid
- amine polymers
- acid sequestrants
- polymers
- binding
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 3
- 150000001412 amines Chemical class 0.000 title abstract 2
- 229920000080 bile acid sequestrant Polymers 0.000 title 1
- 229940096699 bile acid sequestrants Drugs 0.000 title 1
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
- 206010069703 Bile acid malabsorption Diseases 0.000 abstract 1
- 206010012735 Diarrhoea Diseases 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 239000003833 bile salt Substances 0.000 abstract 1
- 229940093761 bile salts Drugs 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0206—Polyalkylene(poly)amines
- C08G73/0213—Preparatory process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
- A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0206—Polyalkylene(poly)amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/024—Polyamines containing oxygen in the form of ether bonds in the main chain
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0246—Polyamines containing other atoms than carbon, hydrogen, nitrogen or oxygen in the main chain
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0246—Polyamines containing other atoms than carbon, hydrogen, nitrogen or oxygen in the main chain
- C08G73/0253—Polyamines containing sulfur in the main chain
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0273—Polyamines containing heterocyclic moieties in the main chain
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/028—Polyamidoamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
- C08L79/02—Polyamines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30782210P | 2010-02-24 | 2010-02-24 | |
| US30782010P | 2010-02-24 | 2010-02-24 | |
| US37368210P | 2010-08-13 | 2010-08-13 | |
| PCT/US2011/026106 WO2011106548A1 (en) | 2010-02-24 | 2011-02-24 | Amine polymers for use as bile acid sequestrants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012009783A MX2012009783A (es) | 2012-11-21 |
| MX348821B true MX348821B (es) | 2017-06-30 |
Family
ID=43901141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012009783A MX348821B (es) | 2010-02-24 | 2011-02-24 | Polímeros de amina para usarse como secuestrantes del ácido biliar. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9655920B2 (enExample) |
| EP (1) | EP2539389B1 (enExample) |
| JP (3) | JP6258586B2 (enExample) |
| KR (1) | KR101822608B1 (enExample) |
| CN (2) | CN102906159B (enExample) |
| AU (2) | AU2011220748B2 (enExample) |
| BR (1) | BR112012021446A2 (enExample) |
| CA (1) | CA2790901C (enExample) |
| DE (1) | DE112011100657T5 (enExample) |
| ES (1) | ES2661079T3 (enExample) |
| GB (1) | GB2490855A (enExample) |
| MX (1) | MX348821B (enExample) |
| RU (2) | RU2017106587A (enExample) |
| WO (1) | WO2011106548A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2549513T3 (es) | 2010-02-24 | 2015-10-28 | Relypsa, Inc. | Polivinilamina, polialilamina y polietilenimina reticuladas para uso como secuestradores de ácidos biliares |
| EP2888223A2 (en) * | 2012-08-24 | 2015-07-01 | Université de Strasbourg | Branched or macrocyclic polyamines and uses thereof |
| WO2014163883A2 (en) * | 2013-03-13 | 2014-10-09 | Elevance Renewable Sciences | Natural oil derivatives including primary amine functional groups |
| KR102633597B1 (ko) * | 2013-06-05 | 2024-02-06 | 트리시다, 인크. | 경구 투여를 위한 양성자-결합 중합체 |
| MA41202A (fr) | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
| CN107613986A (zh) | 2015-04-07 | 2018-01-19 | 英特塞普特医药品公司 | 用于组合疗法的药物组合物 |
| US11090354B2 (en) * | 2015-08-06 | 2021-08-17 | The Johns Hopkins University | Composition and method for treatment of metabolic disorders |
| CN105111089B (zh) * | 2015-09-07 | 2017-05-10 | 南京华威医药科技开发有限公司 | 吡沙洛姆中间体 |
| CN106176800B (zh) * | 2016-07-11 | 2019-12-06 | 韩源平 | 多聚阳离子树脂的制药应用 |
| GB201809627D0 (en) * | 2018-06-12 | 2018-07-25 | Biorelevant Com Ltd | Methods for preparing buffer solutions suitable for in vitro drug dissolution testing, drug solubility testing and/or drug profiling |
| US11524029B2 (en) | 2018-08-13 | 2022-12-13 | Viscera Labs, Inc. | Therapeutic composition and methods |
| US11590161B2 (en) | 2018-08-13 | 2023-02-28 | Viscera Labs, Inc. | Therapeutic composition and methods |
| JP2022548699A (ja) | 2019-09-20 | 2022-11-21 | グライセンド， インコーポレイテッド | 置換フェニルボロン酸含有ポリマーおよび使用方法 |
| EP4578453A4 (en) * | 2022-08-22 | 2026-06-24 | Waterstone Pharmaceuticals Wuhan Co Ltd | AMMONIUM SALT POLYMER, ITS PREPARATION PROCESS AND ITS USE AS A BILE ACID CHELATING AGENT |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3692895A (en) * | 1970-09-08 | 1972-09-19 | Norman A Nelson | Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria |
| JPH066667A (ja) | 1992-06-22 | 1994-01-14 | Canon Inc | ぶれ検出装置及びぶれ補正装置 |
| EP0580079B1 (de) | 1992-07-22 | 1996-12-11 | Hoechst Aktiengesellschaft | Vernetzte, stickstoffhaltige Vinylcopolymere, Verfahren zu ihrer Herstellung sowie die Verwendung dieser Verbindungen |
| ATE159262T1 (de) | 1992-07-22 | 1997-11-15 | Hoechst Ag | Hydrophile zentren aufweisende polyvinylamin- derivate, verfahren zu ihrer herstellung sowie die verwendung der verbindungen als arzneimittel, wirkstoffträger und nahrungsmittelhilfsstoff |
| DK0656029T3 (da) * | 1992-08-20 | 1999-02-15 | Du Pont | Tværbundne polymere ammoniumsalte |
| US5631365A (en) | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
| US5414068A (en) | 1994-01-24 | 1995-05-09 | Rohm And Haas Company | Crosslinked anion exchange particles and method for producing the particles |
| TW474813B (en) * | 1994-06-10 | 2002-02-01 | Geltex Pharma Inc | Alkylated composition for removing bile salts from a patient |
| AU3649697A (en) | 1996-06-27 | 1998-01-14 | G.D. Searle & Co. | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
| US6083497A (en) * | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| US7425579B2 (en) * | 1998-04-21 | 2008-09-16 | Universite Laval | Methods for inhibiting activity of polyamine transporters |
| US6294163B1 (en) | 1998-10-02 | 2001-09-25 | Geltex Pharmaceuticals, Inc. | Polymers containing guanidinium groups as bile acid sequestrants |
| AU2374800A (en) * | 1998-12-23 | 2000-07-31 | Geltex Pharmaceuticals, Inc. | Amine condensation polymer bile acid sequestrants |
| US7459502B2 (en) * | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| US7335795B2 (en) | 2004-03-22 | 2008-02-26 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7608674B2 (en) * | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| CA2551528A1 (en) | 2003-12-31 | 2005-07-21 | Genzyme Corporation | Enteric coated aliphatic amine polymer bile acid sequestrants |
| ES2342947T3 (es) * | 2004-10-13 | 2010-07-19 | Ilypsa, Inc. | Polimeros de amina reticulados. |
| EP2484677A1 (en) * | 2005-01-21 | 2012-08-08 | Basf Se | Polyamine derivative |
| JP2009536246A (ja) * | 2006-05-05 | 2009-10-08 | ゲンズイメ コーポレーション | ホスフェート捕捉剤としてのアミン縮合重合体 |
| US20100124542A1 (en) | 2006-07-18 | 2010-05-20 | Genzyme Corporation | Amine dendrimers |
| WO2008027551A2 (en) | 2006-09-01 | 2008-03-06 | Genzyme Corporation | Dendrimer compositions |
| JP2010513271A (ja) | 2006-12-14 | 2010-04-30 | ゲンズイメ コーポレーション | アミド−アミンポリマー組成物 |
| US20100129309A1 (en) * | 2007-02-23 | 2010-05-27 | Dhal Pradeep K | Amine polymer compositions |
| EP2152277A1 (en) | 2007-04-27 | 2010-02-17 | Genzyme Corporation | Amido-amine dendrimer compositions |
| WO2009023544A2 (en) * | 2007-08-10 | 2009-02-19 | Ilypsa, Inc. | Dosage unit anion-exchange polymer pharmaceutical compositions |
| JP5332520B2 (ja) * | 2007-11-07 | 2013-11-06 | アステラス製薬株式会社 | 医薬用錠剤 |
| WO2009097127A1 (en) | 2008-01-31 | 2009-08-06 | Genzyme Corporation | Pharmaceutical compositions |
| WO2009122400A1 (en) | 2008-03-31 | 2009-10-08 | Semorex Inc. | Phosphate binding polymers |
| US20110129433A1 (en) | 2008-06-26 | 2011-06-02 | Ironwood Pharmaceuticals, Inc. | Compositions and Methods for Treating or Preventing Gastrointestinal Disorders and GERD-Related Respiratory Disorders |
| BR112012021448A2 (pt) | 2010-02-24 | 2016-05-31 | Relypsa Inc | polímero de amina, método para tratar doença, método de remoção de sais biliares de um indivíduo animal, método para melhorar o controle glicêmico em um indivíduo, e, processo para preparar o polímero de amina. |
| ES2549513T3 (es) | 2010-02-24 | 2015-10-28 | Relypsa, Inc. | Polivinilamina, polialilamina y polietilenimina reticuladas para uso como secuestradores de ácidos biliares |
-
2011
- 2011-02-24 RU RU2017106587A patent/RU2017106587A/ru not_active Application Discontinuation
- 2011-02-24 BR BR112012021446A patent/BR112012021446A2/pt not_active Application Discontinuation
- 2011-02-24 MX MX2012009783A patent/MX348821B/es active IP Right Grant
- 2011-02-24 KR KR1020127024557A patent/KR101822608B1/ko not_active Expired - Fee Related
- 2011-02-24 WO PCT/US2011/026106 patent/WO2011106548A1/en not_active Ceased
- 2011-02-24 ES ES11706453.5T patent/ES2661079T3/es active Active
- 2011-02-24 CA CA2790901A patent/CA2790901C/en not_active Expired - Fee Related
- 2011-02-24 DE DE112011100657T patent/DE112011100657T5/de not_active Withdrawn
- 2011-02-24 GB GB1216820.9A patent/GB2490855A/en not_active Withdrawn
- 2011-02-24 CN CN201180019265.0A patent/CN102906159B/zh not_active Expired - Fee Related
- 2011-02-24 EP EP11706453.5A patent/EP2539389B1/en not_active Not-in-force
- 2011-02-24 AU AU2011220748A patent/AU2011220748B2/en not_active Ceased
- 2011-02-24 RU RU2012140432A patent/RU2612795C2/ru active
- 2011-02-24 JP JP2012555155A patent/JP6258586B2/ja not_active Expired - Fee Related
- 2011-02-24 US US13/581,148 patent/US9655920B2/en not_active Expired - Fee Related
- 2011-02-24 CN CN201710479049.3A patent/CN107266681A/zh active Pending
-
2016
- 2016-02-04 AU AU2016200700A patent/AU2016200700B2/en not_active Ceased
- 2016-03-24 JP JP2016059918A patent/JP2016130320A/ja active Pending
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2017
- 2017-05-22 US US15/601,291 patent/US20170258825A1/en not_active Abandoned
- 2017-07-21 JP JP2017141886A patent/JP6622760B2/ja not_active Expired - Fee Related
Also Published As
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|---|---|
| EP2539389B1 (en) | 2017-12-20 |
| KR101822608B1 (ko) | 2018-01-29 |
| WO2011106548A1 (en) | 2011-09-01 |
| US20140356316A1 (en) | 2014-12-04 |
| JP6258586B2 (ja) | 2018-01-10 |
| JP2017190464A (ja) | 2017-10-19 |
| CA2790901C (en) | 2018-05-01 |
| AU2011220748B2 (en) | 2015-11-05 |
| AU2016200700B2 (en) | 2017-08-17 |
| AU2016200700A1 (en) | 2016-02-25 |
| RU2012140432A (ru) | 2014-03-27 |
| KR20120130227A (ko) | 2012-11-29 |
| US20170258825A1 (en) | 2017-09-14 |
| GB2490855A (en) | 2012-11-14 |
| CN102906159B (zh) | 2017-09-26 |
| ES2661079T3 (es) | 2018-03-27 |
| CN107266681A (zh) | 2017-10-20 |
| US9655920B2 (en) | 2017-05-23 |
| EP2539389A1 (en) | 2013-01-02 |
| CA2790901A1 (en) | 2011-09-01 |
| AU2011220748A1 (en) | 2012-09-20 |
| BR112012021446A2 (pt) | 2016-05-31 |
| CN102906159A (zh) | 2013-01-30 |
| DE112011100657T5 (de) | 2013-02-28 |
| MX2012009783A (es) | 2012-11-21 |
| JP6622760B2 (ja) | 2019-12-18 |
| GB201216820D0 (en) | 2012-11-07 |
| JP2016130320A (ja) | 2016-07-21 |
| RU2612795C2 (ru) | 2017-03-13 |
| RU2017106587A (ru) | 2019-01-21 |
| JP2013520563A (ja) | 2013-06-06 |
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