MX347467B - Comprimidos de ibuprofeno de sodio y procedimientos de fabricación de composiciones farmacéuticas que incluyen ibuprofeno de sodio. - Google Patents

Comprimidos de ibuprofeno de sodio y procedimientos de fabricación de composiciones farmacéuticas que incluyen ibuprofeno de sodio.

Info

Publication number
MX347467B
MX347467B MX2015011691A MX2015011691A MX347467B MX 347467 B MX347467 B MX 347467B MX 2015011691 A MX2015011691 A MX 2015011691A MX 2015011691 A MX2015011691 A MX 2015011691A MX 347467 B MX347467 B MX 347467B
Authority
MX
Mexico
Prior art keywords
sodium ibuprofen
tablets
methods
pharmaceutical compositions
compositions including
Prior art date
Application number
MX2015011691A
Other languages
English (en)
Inventor
Jeffery J Seyer
Amy L Conder
Angela P Taylor
Bonny Rene Shaw
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of MX347467B publication Critical patent/MX347467B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Abstract

Se describen composiciones de ibuprofeno de sodio y procedimientos de fabricación de comprimidos y comprimidos oblongos que comprenden ibuprofeno de sodio; la formulación es ventajosa porque permite la formación de comprimidos que tienen bajo contenido de sodio y proporciona además comprimidos que exhiben estabilidad física mejorada, alta dureza de comprimido y alta resistencia, unido a excelentes características de disolución y de biodisponibilidad; las formulaciones y procesos son además ventajosos porque pueden producirse en grandes cantidades sin un número inaceptable de comprimidos defectuosos.
MX2015011691A 2009-06-22 2010-06-21 Comprimidos de ibuprofeno de sodio y procedimientos de fabricación de composiciones farmacéuticas que incluyen ibuprofeno de sodio. MX347467B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21914909P 2009-06-22 2009-06-22
PCT/US2010/039346 WO2011005478A2 (en) 2009-06-22 2010-06-21 Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen

Publications (1)

Publication Number Publication Date
MX347467B true MX347467B (es) 2017-04-26

Family

ID=42543076

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015011691A MX347467B (es) 2009-06-22 2010-06-21 Comprimidos de ibuprofeno de sodio y procedimientos de fabricación de composiciones farmacéuticas que incluyen ibuprofeno de sodio.
MX2011013912A MX2011013912A (es) 2009-06-22 2010-06-21 Comprimidos de ibuprofeno de sodio y procedimientos de fabricacion de composiciones farmaceuticas que incluyen ibuprofeno de sodio.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2011013912A MX2011013912A (es) 2009-06-22 2010-06-21 Comprimidos de ibuprofeno de sodio y procedimientos de fabricacion de composiciones farmaceuticas que incluyen ibuprofeno de sodio.

Country Status (23)

Country Link
US (4) US20100323005A1 (es)
EP (1) EP2445486B1 (es)
JP (2) JP2012530781A (es)
KR (2) KR101429331B1 (es)
CN (2) CN104922084B (es)
AR (1) AR077189A1 (es)
AU (1) AU2010270976B2 (es)
BR (1) BRPI1010748A2 (es)
CA (1) CA2764740C (es)
CO (1) CO6480926A2 (es)
ES (1) ES2654331T3 (es)
HK (1) HK1213783A1 (es)
HU (1) HUE037827T2 (es)
IL (2) IL216602B (es)
MX (2) MX347467B (es)
NZ (2) NZ620828A (es)
PL (1) PL2445486T3 (es)
PT (1) PT2445486T (es)
RU (3) RU2715680C2 (es)
SG (2) SG176221A1 (es)
TW (3) TWI477270B (es)
WO (1) WO2011005478A2 (es)
ZA (1) ZA201109501B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2965746B1 (en) 2014-07-10 2019-03-13 Santa Farma Ilaç Sanayi A.S. An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate
BR112017028218A2 (pt) * 2015-06-30 2018-08-28 Genentech Inc ?comprimidos de liberação imediata contendo uma droga e processos para formação dos comprimidos?

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US4980375A (en) * 1987-07-10 1990-12-25 Sterling Drug Inc. Onset-hastened/enhanced antipyretic response
GB8813682D0 (en) * 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
US5104648A (en) * 1989-02-02 1992-04-14 Mallinckrodt Specialty Chemicals Company High ibuprofen content granulations
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
UA34430C2 (uk) * 1991-05-13 2001-03-15 Дзе Бутс Компані Плс S(-)-2-(4-ізобутилфеніл)пропіонат натрію дигідрат, придатний для лікування запалення, болю і гіпертермії, фармацевтична композиція на його основі та спосіб одержання s(-)-2-(4-ізобутилфеніл)пропіонату натрію
DE59209706D1 (de) * 1992-12-01 1999-07-08 Spirig Ag S(+)-Ibuprofen enthaltende Arzneimittel
GB9603699D0 (en) * 1996-02-21 1996-04-17 Boots Co Plc Therapeutic composition
AU8668598A (en) * 1997-08-20 1999-03-08 University Of Oklahoma, The Gaba analogs to prevent and treat gastrointestinal damage
JP2002510336A (ja) * 1998-04-11 2002-04-02 エレカッパ・ユウロテラピッチ・ソシエタ・ペル・アチオニ 水溶性ケトプロフェン塩を含有する薬学的調製物及びその使用方法
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.
US20080020042A1 (en) * 2003-10-14 2008-01-24 Peter Gruber Dosage form of sodium ibuprofen
WO2005121061A1 (en) * 2004-06-07 2005-12-22 Strides Research And Specialty Chemicals Limited Novel process for producing ibuprofen sodium dihydrate
US20080085308A1 (en) * 2004-08-12 2008-04-10 Reckitt Benckiser Healthcare (Uk) Limited Granules Comprising Paracetamol, a Nsaid and a Sugar Alchohol Made by Melt Extrusion
EP2043613A1 (en) * 2006-07-14 2009-04-08 Fmc Corporation Solid form
FI20080348A0 (fi) * 2008-02-15 2008-05-09 Atacama Labs Oy Uudenlainen farmaseuttinen formulaatio

Also Published As

Publication number Publication date
IL216602B (en) 2019-09-26
TW201521717A (zh) 2015-06-16
ES2654331T3 (es) 2018-02-13
MX2011013912A (es) 2012-02-23
TWI504393B (zh) 2015-10-21
WO2011005478A3 (en) 2011-11-17
TW201318622A (zh) 2013-05-16
EP2445486A2 (en) 2012-05-02
JP6446413B2 (ja) 2018-12-26
JP2016222696A (ja) 2016-12-28
CN102802613A (zh) 2012-11-28
NZ628603A (en) 2016-04-29
US20170319518A1 (en) 2017-11-09
ZA201109501B (en) 2012-09-26
SG176221A1 (en) 2012-01-30
RU2015122313A (ru) 2018-12-20
US20100323005A1 (en) 2010-12-23
TW201110964A (en) 2011-04-01
JP2012530781A (ja) 2012-12-06
NZ620828A (en) 2014-08-29
PL2445486T3 (pl) 2018-04-30
RU2019140368A (ru) 2021-06-09
US20200009093A1 (en) 2020-01-09
SG10201509312UA (en) 2015-12-30
BRPI1010748A2 (pt) 2016-03-22
CO6480926A2 (es) 2012-07-16
PT2445486T (pt) 2018-01-03
KR101429331B1 (ko) 2014-08-11
IL253975A0 (en) 2017-10-31
RU2011150661A (ru) 2013-07-27
US20150231099A1 (en) 2015-08-20
HUE037827T2 (hu) 2018-09-28
AU2010270976B2 (en) 2014-03-20
KR20120026559A (ko) 2012-03-19
TWI477270B (zh) 2015-03-21
HK1213783A1 (zh) 2016-07-15
CA2764740C (en) 2015-09-01
RU2015122313A3 (es) 2018-12-21
IL216602A0 (en) 2012-02-29
TWI542344B (zh) 2016-07-21
CN104922084B (zh) 2020-01-14
CN104922084A (zh) 2015-09-23
EP2445486B1 (en) 2017-11-08
KR20140053414A (ko) 2014-05-07
CA2764740A1 (en) 2011-01-13
RU2715680C2 (ru) 2020-03-03
AR077189A1 (es) 2011-08-10
WO2011005478A2 (en) 2011-01-13
AU2010270976A1 (en) 2011-12-15

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