MX346094B - Método de administración de vacunas. - Google Patents

Método de administración de vacunas.

Info

Publication number
MX346094B
MX346094B MX2013012219A MX2013012219A MX346094B MX 346094 B MX346094 B MX 346094B MX 2013012219 A MX2013012219 A MX 2013012219A MX 2013012219 A MX2013012219 A MX 2013012219A MX 346094 B MX346094 B MX 346094B
Authority
MX
Mexico
Prior art keywords
delivery method
vaccine delivery
subject
component
physiological
Prior art date
Application number
MX2013012219A
Other languages
English (en)
Other versions
MX2013012219A (es
Inventor
A Harn Donald
Queiroz Rafaella
Mcewen Lisa
Original Assignee
Univ Georgia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgia filed Critical Univ Georgia
Publication of MX2013012219A publication Critical patent/MX2013012219A/es
Publication of MX346094B publication Critical patent/MX346094B/es

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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

La presente invención se refiere a una composición que incluye como un componente matriz de suspensión que es un liquido a temperatura ambiente y un gel en concentraciones salinas fisiológicas y/o temperaturas fisiológicas y como un segundo componente uno o mas antígenos. También incluye métodos para inducir una respuesta inmune en un sujeto y vacunar a un sujeto mediante la administración de las composiciones.
MX2013012219A 2011-04-18 2012-04-18 Método de administración de vacunas. MX346094B (es)

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PT3275507T (pt) 2011-04-18 2020-05-20 Univ Georgia Método de administração de vacina
CN103063846B (zh) * 2012-12-20 2014-08-13 南京医科大学 SjHSP60在制备监测血吸虫病患者综合肝脏病理损伤程度的诊断试剂中的应用
US9149522B2 (en) 2013-09-25 2015-10-06 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9149521B2 (en) 2013-09-25 2015-10-06 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9504743B2 (en) 2013-09-25 2016-11-29 Sequoia Sciences, Inc Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9017698B2 (en) 2013-09-25 2015-04-28 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US20170136127A1 (en) * 2014-07-01 2017-05-18 Vicus Therapeutics, Llc Hydrogels for treating and ameliorating cancers and potentiating the immune system and methods of making and using them
US11472841B2 (en) 2018-01-19 2022-10-18 Menicon Co., Ltd. Immunogenic composition
KR102285977B1 (ko) * 2019-03-15 2021-08-05 대한민국 오일 에멀젼과 병용 투여 가능한 면역증강용 보조물질 및 이를 포함하는 구제역 백신 조성물
CN110423268A (zh) * 2019-04-25 2019-11-08 张胜有 可自组装成水凝胶的多肽、水凝胶及其应用
CN117120088A (zh) * 2021-04-07 2023-11-24 电化株式会社 佐剂活性增强剂和佐剂组合物
CN116440251B (zh) * 2023-03-09 2024-01-05 南京医科大学 血吸虫来源多肽在制备预防和/或治疗缺血再灌注的药物中的应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670483A (en) 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US6841543B1 (en) 1996-01-31 2005-01-11 President And Fellows Of Harvard College Methods of inhibiting production of T helper type 2 cytokines in human immune cells
MXPA01005441A (es) 1998-12-01 2002-03-14 Harvard College Metodos inmunomodulatorios que emplean antigenos de carbohidrato.
US20050214227A1 (en) * 1999-03-08 2005-09-29 Powderject Research Limited Microparticle formulations for sustained-release of bioactive compounds
AU2001276831A1 (en) * 2000-06-22 2002-01-02 Rxkinetix, Inc. Delivery vehicle composition and methods for delivering antigens and other drugs
US20040258702A1 (en) 2000-06-22 2004-12-23 Blonder Joan P. Vaccine delivery
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
CA2489019A1 (en) * 2001-06-15 2002-12-27 Nordic Vaccine Technology A/S Therapeutical vaccination
US20040047866A1 (en) 2002-09-09 2004-03-11 President And Fellows Of Harvard College Immunomodulatory methods using carbohydrate antigens
US7713923B2 (en) 2003-06-25 2010-05-11 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
US20050053667A1 (en) * 2003-07-09 2005-03-10 Darrell Irvine Programmed immune responses using a vaccination node
WO2006055974A2 (en) 2004-11-22 2006-05-26 President And Fellows Of Harvard College Method of treating diseases and disorders
JP2009514839A (ja) 2005-11-04 2009-04-09 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル サイトカイン誘導剤を含むアジュバントインフルエンザワクチン
US20090136991A1 (en) * 2007-11-09 2009-05-28 Jones Douglas E Identifying Naive, Infected, or Vaccinated Mammals
AU2010254550B2 (en) 2009-05-27 2015-10-15 Selecta Biosciences, Inc. Targeted synthetic nanocarriers with pH sensitive release of immunomodulatory agents
PT3275507T (pt) 2011-04-18 2020-05-20 Univ Georgia Método de administração de vacina

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US20170202958A1 (en) 2017-07-20
JP6231474B2 (ja) 2017-11-15
KR20140031904A (ko) 2014-03-13
JP2017019810A (ja) 2017-01-26
NZ616804A (en) 2015-12-24
EP2699318B1 (en) 2017-08-30
US9566338B2 (en) 2017-02-14
KR101974382B1 (ko) 2019-05-03
WO2012145355A1 (en) 2012-10-26
EP2699318A1 (en) 2014-02-26
KR101997836B1 (ko) 2019-07-08
EP3275507A2 (en) 2018-01-31
MX2013012219A (es) 2013-12-16
EP3275507A3 (en) 2018-04-18
US20210015916A1 (en) 2021-01-21
ES2647902T3 (es) 2017-12-27
US20130195910A1 (en) 2013-08-01
CA2833369C (en) 2020-09-08
CA2833369A1 (en) 2012-10-26
KR20190043636A (ko) 2019-04-26
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US20220347295A1 (en) 2022-11-03
CN103648587B (zh) 2021-09-17
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US11524072B2 (en) 2022-12-13
JP6290992B2 (ja) 2018-03-07
BR112013026661B1 (pt) 2020-12-01
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