MX3453E - Procedimiento para preparar un derivado del acido clavulanico - Google Patents
Procedimiento para preparar un derivado del acido clavulanicoInfo
- Publication number
- MX3453E MX3453E MX000141U MX14176U MX3453E MX 3453 E MX3453 E MX 3453E MX 000141 U MX000141 U MX 000141U MX 14176 U MX14176 U MX 14176U MX 3453 E MX3453 E MX 3453E
- Authority
- MX
- Mexico
- Prior art keywords
- preparing
- derivative
- clavulanic acid
- procedure
- formula
- Prior art date
Links
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title 1
- 229960003324 clavulanic acid Drugs 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D503/02—Preparation
- C07D503/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
La presente unvención se refiere a un procedimiento para preparar un derivado del ácido clavulanico de la fórmula: (III) (ver gaceta) y sales y ésteres de los mismos, dicho procedimiento comprende la hidrogenación de un compuesto de la fórmula (IV) (ver gaceta) O-un derivado O-substituído ó una sal o éster del mismo, a una temperatura moderada, en presencia de un disolvente inerte y de un catalizador de un metal de transicion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB15209/75A GB1545467A (en) | 1975-04-14 | 1975-04-14 | Deoxyclavulanic acid and deoxyisoclavulanic acid and derivatives thereof |
GB3967175 | 1975-09-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX3453E true MX3453E (es) | 1980-12-03 |
Family
ID=26251136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX000141U MX3453E (es) | 1975-04-14 | 1976-04-05 | Procedimiento para preparar un derivado del acido clavulanico |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS51127093A (es) |
AR (1) | AR208773A1 (es) |
AT (1) | AT342199B (es) |
AU (1) | AU497577B2 (es) |
CA (1) | CA1074802A (es) |
CH (1) | CH602742A5 (es) |
DE (1) | DE2616088A1 (es) |
DK (1) | DK144066C (es) |
ES (1) | ES446468A1 (es) |
FI (1) | FI760946A (es) |
FR (1) | FR2336130A1 (es) |
GR (1) | GR58256B (es) |
HU (1) | HU175444B (es) |
IE (1) | IE42666B1 (es) |
IL (1) | IL49279A (es) |
LU (1) | LU74749A1 (es) |
MX (1) | MX3453E (es) |
NL (1) | NL7603840A (es) |
NO (1) | NO761241L (es) |
PT (1) | PT64897B (es) |
SE (1) | SE427037B (es) |
YU (1) | YU69476A (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7709876A (nl) * | 1976-09-09 | 1978-03-13 | Glaxo Lab Ltd | Werkwijze voor de bereiding van nieuwe (beta)-laktamen. |
NL7711640A (nl) * | 1976-10-25 | 1978-04-27 | Glaxo Lab Ltd | Werkwijze voor de bereiding van nieuwe clavamderivaten. |
GB9007143D0 (en) * | 1990-03-30 | 1990-05-30 | Beecham Group Plc | Veterinary composition |
-
1976
- 1976-03-12 GR GR50291A patent/GR58256B/el unknown
- 1976-03-12 PT PT64897A patent/PT64897B/pt unknown
- 1976-03-18 YU YU00694/76A patent/YU69476A/xx unknown
- 1976-03-24 IL IL49279A patent/IL49279A/xx unknown
- 1976-03-24 AT AT215576A patent/AT342199B/de not_active IP Right Cessation
- 1976-03-25 IE IE628/76A patent/IE42666B1/en unknown
- 1976-03-29 FR FR7609025A patent/FR2336130A1/fr active Granted
- 1976-03-29 ES ES446468A patent/ES446468A1/es not_active Expired
- 1976-03-31 DK DK156576A patent/DK144066C/da not_active IP Right Cessation
- 1976-03-31 AR AR262754A patent/AR208773A1/es active
- 1976-04-05 MX MX000141U patent/MX3453E/es unknown
- 1976-04-07 FI FI760946A patent/FI760946A/fi not_active Application Discontinuation
- 1976-04-09 NO NO761241A patent/NO761241L/no unknown
- 1976-04-12 LU LU74749A patent/LU74749A1/xx unknown
- 1976-04-12 SE SE7604287A patent/SE427037B/xx unknown
- 1976-04-12 NL NL7603840A patent/NL7603840A/xx not_active Application Discontinuation
- 1976-04-13 DE DE19762616088 patent/DE2616088A1/de not_active Withdrawn
- 1976-04-13 JP JP51042313A patent/JPS51127093A/ja active Pending
- 1976-04-13 CA CA250,165A patent/CA1074802A/en not_active Expired
- 1976-04-13 CH CH470276A patent/CH602742A5/xx not_active IP Right Cessation
- 1976-04-14 AU AU13020/76A patent/AU497577B2/en not_active Expired
- 1976-04-14 HU HU76BE1258A patent/HU175444B/hu unknown
Also Published As
Publication number | Publication date |
---|---|
DK144066C (da) | 1982-05-10 |
SE7604287L (sv) | 1976-10-15 |
ATA215576A (de) | 1977-07-15 |
HU175444B (hu) | 1980-08-28 |
GR58256B (en) | 1977-09-15 |
CH602742A5 (es) | 1978-07-31 |
ES446468A1 (es) | 1977-11-01 |
AU497577B2 (en) | 1978-12-21 |
IE42666L (en) | 1976-10-14 |
FR2336130B1 (es) | 1979-06-22 |
LU74749A1 (es) | 1976-11-11 |
AU1302076A (en) | 1977-10-20 |
CA1074802A (en) | 1980-04-01 |
PT64897B (en) | 1977-08-18 |
DK144066B (da) | 1981-11-30 |
IE42666B1 (en) | 1980-09-24 |
DK156576A (da) | 1976-10-15 |
NO761241L (es) | 1976-10-15 |
AR208773A1 (es) | 1977-02-28 |
FR2336130A1 (fr) | 1977-07-22 |
DE2616088A1 (de) | 1976-10-28 |
IL49279A (en) | 1979-05-31 |
AT342199B (de) | 1978-03-28 |
PT64897A (en) | 1976-04-01 |
NL7603840A (nl) | 1976-10-18 |
IL49279A0 (en) | 1976-06-30 |
SE427037B (sv) | 1983-02-28 |
FI760946A (es) | 1976-10-15 |
JPS51127093A (en) | 1976-11-05 |
YU69476A (en) | 1982-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NL7800352A (nl) | Werkwijze ter bereiding van koolwaterstof- -oplosbare alkyllactonpolyolesters. | |
NL7708943A (nl) | Werkwijze ter bereiding van onverzadigde derivaten van 7-acylamido-3-cefem-4-carbonzuur. | |
MX3453E (es) | Procedimiento para preparar un derivado del acido clavulanico | |
GR36365B (el) | Μεθοδος δια την παρασκευην νεων υποκατεστημενων φαινυλοξεικων εστερων. | |
ES414939A1 (es) | Procedimiento para la obtencion de esteres del acido sulfo-nato-bencilmalonico. | |
NL7603674A (nl) | Werkwijze ter bereiding van nieuwe esters van chrysanthemumzuur. | |
NL7600547A (nl) | Werkwijze ter bereiding van polycarbonzuurpoly- glycidylesters. | |
MX3292E (es) | Procedimiento mejorado para la preparacion de un acido indanil propionico | |
SE7607300L (sv) | Tiaxantenforeningar samt forfarande for framstellning av dem | |
BE595996A (fr) | Procédé de préparation d'esters aryles d'acides carboxyliques. | |
BE841008A (fr) | Procede de synthese des esters des acides thiocarnamiques | |
NL173958B (nl) | Werkwijze ter bereiding van een hydrohalogenide van een ester van 7-amino-3methyl-3-cefem-4-carbonzuur. | |
JPS5219625A (en) | Process for preparation of organophosphorus compounds | |
NL7614045A (nl) | Werkwijze voor het bereiden van (alpha)-aryl-gesub- stitueerde propionzuuralkylesters. | |
GB1006152A (en) | Method for producing dextro-trans-pyrethric acid | |
JPS5217411A (en) | Process for preparation of unsaturated primary alcohol esters | |
MX3301E (es) | Procedimiento para preparar un derivado de prostaglandina | |
FR1140070A (fr) | Procédé pour la production de dérivés des hydroxyacides gras aryliques | |
JPS51138602A (en) | Process for preparing alpha-hydrazino carboxylic acids | |
NL7603757A (nl) | Nieuwe zouten van p-chloorfenoxyazijnzuur-dime- thylaminoethylester, werkwijzen ter bereiding daarvan en geneesmiddelen, die deze zouten bevat- ten. | |
ES297640A1 (es) | Procedimiento para la obtención de compuestos amínicos | |
NL181799C (nl) | Werkwijze ter bereiding van een ester van 6,6,6-trihalogeen-3,3-dimethyl-4-hexeenzuur. | |
FR1082872A (fr) | Nouveau procédé de préparation d'amides d'acides aromatiques substitués et d'aminoacides aliphatiques ainsi que de leurs sels, esters et dérivés | |
GR23384B (el) | Μεθοδος παρασκευης παραγωγων του π-αλκυλο-βενζυλο-τροπινιου. | |
GB1046258A (en) | New 4-carboxyalkylmercapto-5-aryl pyrimidines and a method for their preparation |