MX344494B - Inmunogeno y antiveneno contra el veneno de la araña violinista. - Google Patents
Inmunogeno y antiveneno contra el veneno de la araña violinista.Info
- Publication number
- MX344494B MX344494B MX2011012895A MX2011012895A MX344494B MX 344494 B MX344494 B MX 344494B MX 2011012895 A MX2011012895 A MX 2011012895A MX 2011012895 A MX2011012895 A MX 2011012895A MX 344494 B MX344494 B MX 344494B
- Authority
- MX
- Mexico
- Prior art keywords
- sphingomyelinases
- expression
- immunogen
- loxosceles
- fragments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Insects & Arthropods (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención se refiere a el asilamiento caracterización y expresión de los fragmentos de DNA codificantes de las esfingomielinasas D de 3 especies de araña del género Loxosceles: L. boneti, L. reclusa y L. laeta y sus toxoides. También comprende la producción por medios recombinantes de las esfingomielinasas D activas y sus toxoides su uso como inmunógeno para la producción en vertebrados de anticurpos neutralizantes del veneno correspondiente y de los fragmentos F(ab')2 respectivos. También se incluye el uso de las esfingomielinasas D recomnbinantes como parte de un matriz antigénica útil en la inmunopurificación de anticuerpos y sus fragmentos o como parte de algún dispositivo diagnóstico para corroborar en clínica que el agente causal del estado de envenenamiento de un paciente sea una araña del género Loxosceles. Así mismo, la invención incluye los vectores moleculares para la expresión de los fragmentos de DNA, las cepas que los comprenden, capaces de expresar las SMD de Loxosceles y los métodos para su expresión.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MXPA04008435A MXPA04008435A (es) | 2004-08-31 | 2004-08-31 | Inmunogeno y anti-veneno contra el veneno de la arana violinista. |
| PCT/MX2005/000071 WO2006025718A2 (es) | 2004-08-31 | 2005-08-29 | Inmunógeno y antiveneno contra el veneno de la araña violinista |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX344494B true MX344494B (es) | 2016-12-19 |
Family
ID=36000447
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04008435A MXPA04008435A (es) | 2004-08-31 | 2004-08-31 | Inmunogeno y anti-veneno contra el veneno de la arana violinista. |
| MX2011012895A MX344494B (es) | 2004-08-31 | 2005-08-29 | Inmunogeno y antiveneno contra el veneno de la araña violinista. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04008435A MXPA04008435A (es) | 2004-08-31 | 2004-08-31 | Inmunogeno y anti-veneno contra el veneno de la arana violinista. |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8287860B2 (es) |
| AR (1) | AR055482A1 (es) |
| AU (1) | AU2005280742B2 (es) |
| BR (1) | BRPI0514809A (es) |
| MX (2) | MXPA04008435A (es) |
| WO (1) | WO2006025718A2 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04008435A (es) * | 2004-08-31 | 2006-03-02 | Univ Mexico Nacional Autonoma | Inmunogeno y anti-veneno contra el veneno de la arana violinista. |
| MX367136B (es) | 2012-10-18 | 2019-08-06 | Inosan Biopharma S A Star | Proceso para purificar fragmentos de anticuerpos polivalentes derivados de plasma hiperinmune. |
| IT202000023809A1 (it) * | 2020-10-09 | 2022-04-09 | Craniomed Group S R L | Anatossine e anticorpi per l’uso nella prevenzione e nel trattamento della malattia da coronavirus. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5196193A (en) | 1989-10-31 | 1993-03-23 | Ophidian Pharmaceuticals, Inc. | Antivenoms and methods for making antivenoms |
| MXPA99011191A (es) | 1999-12-03 | 2005-04-04 | Univ Mexico Nacional Autonoma | Inmunogeno, anti-veneno y vacuna contra el venenode la arana viuda negra. |
| MXPA04008435A (es) * | 2004-08-31 | 2006-03-02 | Univ Mexico Nacional Autonoma | Inmunogeno y anti-veneno contra el veneno de la arana violinista. |
-
2004
- 2004-08-31 MX MXPA04008435A patent/MXPA04008435A/es active IP Right Grant
-
2005
- 2005-08-29 MX MX2011012895A patent/MX344494B/es unknown
- 2005-08-29 US US11/574,488 patent/US8287860B2/en active Active
- 2005-08-29 WO PCT/MX2005/000071 patent/WO2006025718A2/es active Application Filing
- 2005-08-29 BR BRPI0514809-0A patent/BRPI0514809A/pt not_active Application Discontinuation
- 2005-08-29 AU AU2005280742A patent/AU2005280742B2/en not_active Ceased
- 2005-08-30 AR ARP050103622A patent/AR055482A1/es not_active Application Discontinuation
-
2012
- 2012-09-11 US US13/610,516 patent/US8541551B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA04008435A (es) | 2006-03-02 |
| US8287860B2 (en) | 2012-10-16 |
| AU2005280742A1 (en) | 2006-03-09 |
| AU2005280742B2 (en) | 2013-01-17 |
| US20110177078A1 (en) | 2011-07-21 |
| AR055482A1 (es) | 2007-08-22 |
| US20130071399A1 (en) | 2013-03-21 |
| WO2006025718A3 (es) | 2006-11-02 |
| WO2006025718A2 (es) | 2006-03-09 |
| US8541551B2 (en) | 2013-09-24 |
| BRPI0514809A (pt) | 2008-06-24 |
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