ATE532065T1 - Antigenziele der autoimmunbedingten schallempfindungsschwerhörigkeit (aisnhl) und entwicklung von tests zur diagnose und behandlung von aisnhl - Google Patents
Antigenziele der autoimmunbedingten schallempfindungsschwerhörigkeit (aisnhl) und entwicklung von tests zur diagnose und behandlung von aisnhlInfo
- Publication number
- ATE532065T1 ATE532065T1 AT03799763T AT03799763T ATE532065T1 AT E532065 T1 ATE532065 T1 AT E532065T1 AT 03799763 T AT03799763 T AT 03799763T AT 03799763 T AT03799763 T AT 03799763T AT E532065 T1 ATE532065 T1 AT E532065T1
- Authority
- AT
- Austria
- Prior art keywords
- aisnhl
- hearing loss
- autoimmune
- treatment
- sensornetine
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 230000001363 autoimmune Effects 0.000 title abstract 3
- 206010011878 Deafness Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 230000010370 hearing loss Effects 0.000 title 1
- 231100000888 hearing loss Toxicity 0.000 title 1
- 208000016354 hearing loss disease Diseases 0.000 title 1
- 101000948121 Cavia porcellus Choline transporter-like protein 2 Proteins 0.000 abstract 2
- 206010011891 Deafness neurosensory Diseases 0.000 abstract 2
- 208000009966 Sensorineural Hearing Loss Diseases 0.000 abstract 2
- 231100000879 sensorineural hearing loss Toxicity 0.000 abstract 2
- 208000023573 sensorineural hearing loss disease Diseases 0.000 abstract 2
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/139,496 US20030082646A1 (en) | 1998-12-29 | 2002-05-06 | Antigenic targets of autoimmune sensorineural hearing loss (AISNHL) and development of tests for diagnosis and management of AISNHL |
| PCT/US2003/014248 WO2004041152A2 (en) | 2002-05-06 | 2003-05-06 | Antigenic targets of autoimmune sensorineural hearing loss (aisnhl) and development of tests fro diagnosis and management of aisnhl |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE532065T1 true ATE532065T1 (de) | 2011-11-15 |
Family
ID=32311697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03799763T ATE532065T1 (de) | 2002-05-06 | 2003-05-06 | Antigenziele der autoimmunbedingten schallempfindungsschwerhörigkeit (aisnhl) und entwicklung von tests zur diagnose und behandlung von aisnhl |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20030082646A1 (de) |
| EP (1) | EP1508043B1 (de) |
| AT (1) | ATE532065T1 (de) |
| AU (1) | AU2003299473A1 (de) |
| CA (1) | CA2489275C (de) |
| WO (1) | WO2004041152A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030082646A1 (en) * | 1998-12-29 | 2003-05-01 | The Regents Of The University Of Michigan | Antigenic targets of autoimmune sensorineural hearing loss (AISNHL) and development of tests for diagnosis and management of AISNHL |
| US7829292B2 (en) * | 2002-05-06 | 2010-11-09 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing, predicting therapeutic response of, and monitoring autoimmune disease |
| EP1533319B1 (de) * | 2002-06-27 | 2011-01-12 | Nippon Medical School Foundation | Verfahren zum nachweis von perilymphatischen fisteln |
| WO2006113723A2 (en) | 2005-04-18 | 2006-10-26 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing, predicting therapeutic response of, and monitoring autoimmune disease |
| WO2008070236A2 (en) * | 2006-09-07 | 2008-06-12 | The Cleveland Clinic Foundation | Diagnostic assay for detecting and monitoring hearing loss |
| DE102008045696A1 (de) | 2008-09-04 | 2010-03-11 | Drk Blutspendedienst West Ggmbh | Granulozyten HNA-3a/b-Antigen |
| WO2020188573A1 (en) * | 2019-03-21 | 2020-09-24 | Gamida-Cell Ltd. | Expanded nk cell fractions for transplantation in combination therapy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208479A (en) * | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
| US5422282A (en) * | 1991-04-29 | 1995-06-06 | The Regents Of The University Of California | Methods for detecting autoimmune sensorineural hearing loss |
| US20010006788A1 (en) * | 1998-12-29 | 2001-07-05 | Thomas E. Carey | Identifying the antigenic target of autoimmune sensorineural hearing loss (aisnhl) and developement of specific tests for diagnosis and management of aisnhl |
| US20030082646A1 (en) * | 1998-12-29 | 2003-05-01 | The Regents Of The University Of Michigan | Antigenic targets of autoimmune sensorineural hearing loss (AISNHL) and development of tests for diagnosis and management of AISNHL |
| FR2800750B1 (fr) * | 1999-11-05 | 2003-01-31 | Centre Nat Rech Scient | Proteines membranaires ctl (choline transporter like) impliquees dans le transport de la choline |
| US20030022195A1 (en) * | 2001-02-01 | 2003-01-30 | Millennium Pharmaceuticals, Inc. | 59914 and 59921, choline transporters and uses therefor |
-
2002
- 2002-05-06 US US10/139,496 patent/US20030082646A1/en not_active Abandoned
-
2003
- 2003-05-06 AT AT03799763T patent/ATE532065T1/de active
- 2003-05-06 AU AU2003299473A patent/AU2003299473A1/en not_active Abandoned
- 2003-05-06 CA CA2489275A patent/CA2489275C/en not_active Expired - Fee Related
- 2003-05-06 EP EP03799763A patent/EP1508043B1/de not_active Expired - Lifetime
- 2003-05-06 WO PCT/US2003/014248 patent/WO2004041152A2/en not_active Ceased
-
2008
- 2008-03-25 US US12/055,173 patent/US20090075268A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1508043B1 (de) | 2011-11-02 |
| WO2004041152A2 (en) | 2004-05-21 |
| CA2489275A1 (en) | 2004-05-21 |
| WO2004041152A3 (en) | 2004-10-14 |
| EP1508043A2 (de) | 2005-02-23 |
| US20090075268A1 (en) | 2009-03-19 |
| CA2489275C (en) | 2012-12-18 |
| EP1508043A4 (de) | 2006-09-06 |
| US20030082646A1 (en) | 2003-05-01 |
| AU2003299473A1 (en) | 2004-06-07 |
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