MX336586B - Nuevos peptidos con efectos analgesicos y que inhiben los canales asic. - Google Patents

Nuevos peptidos con efectos analgesicos y que inhiben los canales asic.

Info

Publication number
MX336586B
MX336586B MX2013001020A MX2013001020A MX336586B MX 336586 B MX336586 B MX 336586B MX 2013001020 A MX2013001020 A MX 2013001020A MX 2013001020 A MX2013001020 A MX 2013001020A MX 336586 B MX336586 B MX 336586B
Authority
MX
Mexico
Prior art keywords
peptides
asic channels
channels
analgesic effects
inhibit asic
Prior art date
Application number
MX2013001020A
Other languages
English (en)
Spanish (es)
Other versions
MX2013001020A (es
Inventor
Lingueglia Eric
Sylvie Diochot
Anne Baron-Forster
Miguel Salinas
Michel Lazdunski
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of MX2013001020A publication Critical patent/MX2013001020A/es
Publication of MX336586B publication Critical patent/MX336586B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2013001020A 2010-07-26 2011-07-26 Nuevos peptidos con efectos analgesicos y que inhiben los canales asic. MX336586B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1003136A FR2963010B1 (fr) 2010-07-26 2010-07-26 Nouveaux peptides avec des effets analgesiques et inhibant les canaux asic
PCT/FR2011/051800 WO2012022894A1 (fr) 2010-07-26 2011-07-26 Nouveaux peptides avec des effets analgesiques et inhibant les canaux asic

Publications (2)

Publication Number Publication Date
MX2013001020A MX2013001020A (es) 2014-04-14
MX336586B true MX336586B (es) 2016-01-21

Family

ID=43589927

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013001020A MX336586B (es) 2010-07-26 2011-07-26 Nuevos peptidos con efectos analgesicos y que inhiben los canales asic.

Country Status (13)

Country Link
US (1) US8987207B2 (OSRAM)
EP (1) EP2598523B1 (OSRAM)
JP (1) JP6000245B2 (OSRAM)
CN (1) CN103097404B (OSRAM)
AU (1) AU2011290589A1 (OSRAM)
BR (1) BR112013001863A2 (OSRAM)
CA (1) CA2806471C (OSRAM)
FR (1) FR2963010B1 (OSRAM)
MX (1) MX336586B (OSRAM)
RU (1) RU2583299C2 (OSRAM)
SG (1) SG187877A1 (OSRAM)
WO (1) WO2012022894A1 (OSRAM)
ZA (1) ZA201300662B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105233286B (zh) * 2015-09-10 2018-10-30 上海交通大学医学院 含酸敏感离子通道调控剂的制剂及其在治疗瘙痒中的用途
CN105412932B (zh) * 2015-10-26 2019-08-16 上海交通大学医学院 含ASIC1a与RIP1结合抑制剂的制剂及其抑制神经元死亡的用途
CN112618722A (zh) * 2016-11-22 2021-04-09 上海交通大学医学院 酸敏感离子通道调控剂的用途
CN107384952A (zh) * 2017-08-23 2017-11-24 湖南甲骨文生物医药有限公司 用于筛选ASICs作用蛋白的酵母双杂交诱饵载体的构建方法
CN114729034B (zh) * 2019-06-04 2024-01-12 上海科技大学 亲和力成熟的抗ASIC1a抗体
RU2768484C1 (ru) * 2021-05-24 2022-03-24 Закрытое акционерное общество "СКАЙ ЛТД" Фармацевтическая композиция иммуностимулирующих веществ мурамилпептидной природы

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776896A (en) 1996-01-03 1998-07-07 Zeneca Limited Analgesic peptides from venom of grammostola spatulata and use thereof
JP4959226B2 (ja) * 2006-05-19 2012-06-20 独立行政法人産業技術総合研究所 スリーフィンガー様蛋白質ライブラリ
JP2008193923A (ja) * 2007-02-09 2008-08-28 Janusys Kk 蛋白質ライブラリ

Also Published As

Publication number Publication date
SG187877A1 (en) 2013-03-28
EP2598523A1 (fr) 2013-06-05
CA2806471A1 (fr) 2012-02-23
ZA201300662B (en) 2013-09-25
FR2963010B1 (fr) 2014-08-15
AU2011290589A1 (en) 2013-03-07
US20130196923A1 (en) 2013-08-01
RU2013108262A (ru) 2014-09-10
CN103097404B (zh) 2015-09-16
JP2013535965A (ja) 2013-09-19
MX2013001020A (es) 2014-04-14
CA2806471C (fr) 2020-07-07
RU2583299C2 (ru) 2016-05-10
US8987207B2 (en) 2015-03-24
WO2012022894A4 (fr) 2012-04-12
FR2963010A1 (fr) 2012-01-27
WO2012022894A1 (fr) 2012-02-23
EP2598523B1 (fr) 2015-09-09
JP6000245B2 (ja) 2016-09-28
CN103097404A (zh) 2013-05-08
BR112013001863A2 (pt) 2016-05-31

Similar Documents

Publication Publication Date Title
PH12020550156A1 (en) 4-1bb binding molecules
MX2013001020A (es) Nuevos peptidos con efectos analgesicos y que inhiben los canales asic.
BR112012029975A2 (pt) peptídeo como medicamento, em particular para o tratamento do câncer.
AR068552A1 (es) Polipeptidos y polinucleotidos del fago omegamru y sus usos para detectar, apuntar e inhibir celulas microbianas metanogenicas
MX2014009975A (es) Composiciones del vector aav y metodos para su transferencia genetica a celulas, organos y tejidos.
MY161268A (en) PEPTIDE OR PEPTIDE COMPLEX BINDING TO α2 INTEGRIN AND METHODS AND USES INVOLVING THE SAME
MX337984B (es) Variantes de alfa amilasa y polinucleotidos que codifican la misma.
IN2014CN04586A (OSRAM)
EP4253534A3 (en) Alpha-amylase variants and polynucleotides encoding same
MX2013004892A (es) Polipeptidos que tienen actividad de fosfolipasa c y polinucleotidos que codifican los mismos.
MX356625B (es) Oligonucleotidos para elaborar un cambio en la secuencia de una molécula de ácido ribonucleico objetivo presente en una célula viva.
MX2013007716A (es) Sistemas de expresion.
EA201590162A1 (ru) МУТАНТНЫЕ ФРАГМЕНТЫ OspA И СВЯЗАННЫЕ С НИМИ СПОСОБЫ И ПРИМЕНЕНИЕ
MX2014004598A (es) Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
WO2013119302A3 (en) Gh61 polypeptide variants and polynucleotides encoding same
IN2014DN06164A (OSRAM)
EP3279320A3 (en) Gh61 polypeptide variants and polynucleotides encoding same
EP2488641A4 (en) SUPERGESPULED MINICIRCLE DNA FOR GENE THERAPY APPLICATIONS
RU2015112625A (ru) Пептид, применение пептида для лечения сердечно-сосудистых заболеваний, нуклеотидная последовательность, вектор экспрессии, хозяйская клетка, фармацевтическая композиция
MY173686A (en) Fc gamma receptor iib variants
WO2009111336A3 (en) Methods of purifying plasmid dna
WO2013181404A3 (en) COMPOSITIONS AND METHODS FOR PEPTIDE EXPRESSION AND PURIFICATION USING A TYPE lll SECRETION SYSTEM
PH12014500720A1 (en) Topk peptides and vaccines including the same
MX350713B (es) Variantes de subtilisina y polinucleotidos que las codifican.
WO2009106532A3 (en) Use of prokaryotic tir-domain containing proteins as therapeutic and diagnostic agents