MX2024010009A - Formas de dosificacion oral de agonista de tr\03b2 vk2809 para el tratamiento de trastornos hepaticos y metodos de preparacion de las mismas. - Google Patents

Formas de dosificacion oral de agonista de tr\03b2 vk2809 para el tratamiento de trastornos hepaticos y metodos de preparacion de las mismas.

Info

Publication number
MX2024010009A
MX2024010009A MX2024010009A MX2024010009A MX2024010009A MX 2024010009 A MX2024010009 A MX 2024010009A MX 2024010009 A MX2024010009 A MX 2024010009A MX 2024010009 A MX2024010009 A MX 2024010009A MX 2024010009 A MX2024010009 A MX 2024010009A
Authority
MX
Mexico
Prior art keywords
dosage forms
oral dosage
trî2
agonist
preparing
Prior art date
Application number
MX2024010009A
Other languages
English (en)
Spanish (es)
Inventor
Brian Lian
Geoffrey E Barker
Maureen Barnes
William Hoye
Original Assignee
Viking Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viking Therapeutics Inc filed Critical Viking Therapeutics Inc
Publication of MX2024010009A publication Critical patent/MX2024010009A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2024010009A 2022-02-18 2023-02-13 Formas de dosificacion oral de agonista de tr\03b2 vk2809 para el tratamiento de trastornos hepaticos y metodos de preparacion de las mismas. MX2024010009A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263311905P 2022-02-18 2022-02-18
US202263312650P 2022-02-22 2022-02-22
PCT/US2023/012935 WO2023158616A1 (en) 2022-02-18 2023-02-13 ORAL DOSAGE FORMS OF TRβ AGONIST VK2809 FOR THE TREATMENT OF LIVER DISORDERS AND METHODS OF PREPARING THE SAME

Publications (1)

Publication Number Publication Date
MX2024010009A true MX2024010009A (es) 2024-08-22

Family

ID=87578867

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024010009A MX2024010009A (es) 2022-02-18 2023-02-13 Formas de dosificacion oral de agonista de tr\03b2 vk2809 para el tratamiento de trastornos hepaticos y metodos de preparacion de las mismas.

Country Status (9)

Country Link
US (1) US20250134913A1 (https=)
EP (1) EP4479062A4 (https=)
JP (1) JP2025505802A (https=)
KR (1) KR20240149941A (https=)
CN (1) CN119072316A (https=)
AU (1) AU2023220955A1 (https=)
CA (1) CA3251549A1 (https=)
MX (1) MX2024010009A (https=)
WO (1) WO2023158616A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3053674T3 (en) 2018-03-22 2026-01-23 Viking Therapeutics Inc Crystalline forms and methods of producing crystalline forms of a compound
WO2020117962A1 (en) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation
CN118615254A (zh) * 2023-03-08 2024-09-10 甘莱制药有限公司 片剂及其制备方法与用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL372247A1 (en) * 2002-02-01 2005-07-11 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
CL2004001884A1 (es) * 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
WO2007109605A2 (en) * 2006-03-20 2007-09-27 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions
CN116942684A (zh) * 2020-02-20 2023-10-27 甘莱制药有限公司 一种用于治疗脂肪性肝炎的药物组合物及其制备方法
US11752161B2 (en) * 2020-03-27 2023-09-12 Gannex Pharma Co., Ltd. Pharmaceutical compositions, method of making and method of using thereof
JP7470204B2 (ja) * 2020-03-27 2024-04-17 ガンネックス ファーマ カンパニー リミテッド 医薬組成物、その調製方法及び使用方法
TW202315608A (zh) * 2021-07-06 2023-04-16 中國大陸商甘萊製藥有限公司 用於治療肝臟疾病的聯合治療

Also Published As

Publication number Publication date
EP4479062A4 (en) 2026-03-04
JP2025505802A (ja) 2025-02-28
US20250134913A1 (en) 2025-05-01
KR20240149941A (ko) 2024-10-15
CA3251549A1 (en) 2023-08-24
EP4479062A1 (en) 2024-12-25
CN119072316A (zh) 2024-12-03
AU2023220955A1 (en) 2024-08-15
WO2023158616A1 (en) 2023-08-24

Similar Documents

Publication Publication Date Title
MX2024010009A (es) Formas de dosificacion oral de agonista de tr\03b2 vk2809 para el tratamiento de trastornos hepaticos y metodos de preparacion de las mismas.
CA2691667C (en) Method for the production of a pharmaceutical containing tadalafil
JP6530845B2 (ja) イルベサルタンとアムロジピンまたはその塩を含有する医薬組成物の安定化方法
NO340156B1 (no) Fremgangsmåte for fremstilling av en fast, oralt administrerbar farmasøytisk sammensetning
JP2005320354A5 (https=)
IL102777A (en) Pharmaceutical combination formulation
CA2447005A1 (en) Oral controlled release pharmaceutical composition for one-a-day therapy for the treatment and prophylaxis of cardiac and circulatory diseases
RU2014131238A (ru) Состав с отсроченным высвобождением для уменьшения частоты мочеиспускания и способ его применения
US8758818B2 (en) Oral tablet compositions of dexlansoprazole
KR101895962B1 (ko) 알리사르탄 이소프록실 고체 분산체 및 이를 포함하는 약제학적 조성물
JP2019514993A5 (https=)
KR20170009897A (ko) 알리사르탄 이소프록실 고체 분산체 및 이의 약제학적 조성물
AU2015349896A1 (en) Pharmaceutical bead formulations comprising dimethyl fumarate
JP6618736B2 (ja) ミラベグロン含有錠剤、ミラベグロン含有製剤の製造方法及びミラベグロン含有造粒物の製造方法
KR20180097623A (ko) 아프레밀라스트 서방형 제제
HRP20251276T1 (hr) Postupak za kristalizaciju aktivnih farmaceutskih sastojaka
CN101854921B (zh) 用于口服施用ppi的药物制剂
EP2564832A1 (en) Solid dosage form of HIV protease inhibitors
JPH08301789A (ja) 活性化合物の調節された放出性を有する製剤およびそれらの製造方法
EP3925601A1 (en) Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor
CN107823166A (zh) 一种利伐沙班片的制备方法
WO2025003956A1 (en) High drug loading formulations of encorafenib
CN114533690B (zh) 含抗凝血药物西洛他唑的新制剂及其制备方法
JP2017523164A (ja) コハク酸メトプロロールのカプセル剤形
CA2433915A1 (en) Improved controlled release oral dosage form