MX2023004831A - Metodos para reducir tau en sujetos humanos. - Google Patents

Metodos para reducir tau en sujetos humanos.

Info

Publication number
MX2023004831A
MX2023004831A MX2023004831A MX2023004831A MX2023004831A MX 2023004831 A MX2023004831 A MX 2023004831A MX 2023004831 A MX2023004831 A MX 2023004831A MX 2023004831 A MX2023004831 A MX 2023004831A MX 2023004831 A MX2023004831 A MX 2023004831A
Authority
MX
Mexico
Prior art keywords
tau
methods
human subjects
reducing tau
reducing
Prior art date
Application number
MX2023004831A
Other languages
English (en)
Spanish (es)
Inventor
Wendy R Galpern
Maarten Timmers
Tom Lieven K Jacobs
Partha Nandy
Lingjue Li
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2023004831A publication Critical patent/MX2023004831A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
MX2023004831A 2020-10-26 2021-10-25 Metodos para reducir tau en sujetos humanos. MX2023004831A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063105804P 2020-10-26 2020-10-26
PCT/EP2021/079543 WO2022090158A1 (en) 2020-10-26 2021-10-25 Methods of reducing tau in human subjects

Publications (1)

Publication Number Publication Date
MX2023004831A true MX2023004831A (es) 2023-07-12

Family

ID=78402146

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023004831A MX2023004831A (es) 2020-10-26 2021-10-25 Metodos para reducir tau en sujetos humanos.

Country Status (11)

Country Link
US (1) US20220127345A1 (https=)
EP (1) EP4232155A1 (https=)
JP (1) JP2023546504A (https=)
KR (1) KR20230093499A (https=)
CN (1) CN116916955A (https=)
AU (1) AU2021367878A1 (https=)
CA (1) CA3199806A1 (https=)
IL (1) IL302386A (https=)
MX (1) MX2023004831A (https=)
TW (1) TW202233666A (https=)
WO (1) WO2022090158A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3093200A1 (en) 2018-03-05 2019-09-12 Janssen Pharmaceutica Nv Anti-phf-tau antibodies and uses thereof
JP7379764B1 (ja) 2022-08-09 2023-11-15 レール・リキード-ソシエテ・アノニム・プール・レテュード・エ・レクスプロワタシオン・デ・プロセデ・ジョルジュ・クロード 空気分離装置および空気分離方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
JP6214161B2 (ja) * 2009-12-21 2017-10-18 ジェネンテック, インコーポレイテッド 抗体製剤
ITMI20120814A1 (it) * 2012-05-11 2013-11-12 Diego Dolcetta Somministrazione intratecale, preferibilmente intraventricolare, di inibitori di mtor per la terapia di alcune malattie neurodegenerative, neuro-infiammatorie, neuro-oncologiche
US8980270B2 (en) * 2013-01-18 2015-03-17 Ipierian, Inc. Methods of treating a tauopathy
CN117820467A (zh) * 2016-12-07 2024-04-05 基因泰克公司 抗tau抗体和使用方法
TWI771389B (zh) * 2017-03-16 2022-07-21 美商健生生物科技公司 抗phf-tau抗體及其用途
MA53338A (fr) * 2018-03-05 2022-01-05 Janssen Pharmaceutica Nv Dosages pour détecter la neurodégénérescence
WO2020223279A1 (en) * 2019-04-29 2020-11-05 Voyager Therapeutics, Inc. VECTORIZED ANTIBODIES (vAb) AND USES THEREOF
EP4232472A1 (en) * 2020-10-26 2023-08-30 JANSSEN Pharmaceutica NV Method of safe administration of anti-tau antibody

Also Published As

Publication number Publication date
TW202233666A (zh) 2022-09-01
US20220127345A1 (en) 2022-04-28
KR20230093499A (ko) 2023-06-27
IL302386A (en) 2023-06-01
CA3199806A1 (en) 2022-05-05
AU2021367878A1 (en) 2023-06-22
JP2023546504A (ja) 2023-11-02
EP4232155A1 (en) 2023-08-30
WO2022090158A1 (en) 2022-05-05
CN116916955A (zh) 2023-10-20

Similar Documents

Publication Publication Date Title
MY209590A (en) Anti-msr1 antibodies and methods of use thereof
AU2018263862A1 (en) Stable formulations of programmed death receptor 1 (PD-1) antibodies and methods of use thereof
MX2024011615A (es) Anticuerpos de union a cd3.
MX2024005027A (es) Anticuerpos de union a cd3.
WO2019234241A8 (en) ANTI-oxMIF/ANTI-CD3 ANTIBODY FOR CANCER TREATMENT
WO2019186276A3 (en) Antibody-based methods of detecting and treating alzheimer's disease
WO2020006374A3 (en) Anti-sirp-beta1 antibodies and methods of use thereof
MX2018016183A (es) Anticuerpos especificos del ligando 1 de muerte programada y metodos de uso de los mismos.
MX2023004831A (es) Metodos para reducir tau en sujetos humanos.
MX2020008718A (es) Anticuerpos de union a bcma y usos de los mismos.
WO2019204462A3 (en) Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs
MX2025003476A (es) Anticuerpos anti-il-27 y usos de los mismos
WO2018116267A3 (en) Methods of treatment with anti-factor xi/xia antibodies
MY204235A (en) Antibodies specific for cd3 and uses thereof
WO2021087368A3 (en) Anti-cd45 antibodies and conjugates thereof
WO2014007982A3 (en) C-terminal and central epitope a-beta antibodies
MX2023004280A (es) Composiciones y metodos para el tratamiento de la enfermedad ocular tiroidea.
WO2020247929A8 (en) High affinity anti-cd3 antibodies, and methods for their generation and use
EP4653462A3 (en) Anti-pd-1 antibodies, or fragments thereof, for treating hepatitis b
MX2019011624A (es) Metodos y composiciones para la reduccion de la inmunogenicidad.
MX2024005430A (es) Composiciones, formas farmaceuticas y metodos de anticuerpos anti-tau.
MX2021004226A (es) Terapia combinada contra el cáncer.
MX2022001403A (es) Metodos de administracion de anticuerpos anti-siglec-8 y corticosteroides.
CA3242661A1 (en) Compositions and methods for treatment of thyroid eye disease
WO2023133485A3 (en) Compositions and methods for treatment of thyroid eye disease