MX2023004729A - Composiciones y metodos de vacunacion contra neisseria gonorrhoeae. - Google Patents
Composiciones y metodos de vacunacion contra neisseria gonorrhoeae.Info
- Publication number
- MX2023004729A MX2023004729A MX2023004729A MX2023004729A MX2023004729A MX 2023004729 A MX2023004729 A MX 2023004729A MX 2023004729 A MX2023004729 A MX 2023004729A MX 2023004729 A MX2023004729 A MX 2023004729A MX 2023004729 A MX2023004729 A MX 2023004729A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- lipoprotein
- compositions
- neisseria gonorrhoeae
- vaccination against
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 241000588652 Neisseria gonorrhoeae Species 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- 102000004895 Lipoproteins Human genes 0.000 abstract 4
- 108090001030 Lipoproteins Proteins 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 206010018612 Gonorrhoea Diseases 0.000 abstract 1
- 208000034762 Meningococcal Infections Diseases 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/101—Plasmid DNA for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
La divulgación provee composiciones, y métodos de uso de las mismas, para vacunas para el tratamiento de una infección gonocócica y/o meningocócica, que comprenden vesículas nativas de membrana externa (NOMV) derivadas de bacterias que contienen una proteína gonocócica, que es una lipoproteína o que se modifica para que sea una lipoproteína. También se proveen cepas meningocócicas que contienen un gen que codifica una proteína gonocócica, que es una lipoproteína o que se modifica para que sea una lipoproteína.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063104819P | 2020-10-23 | 2020-10-23 | |
PCT/US2021/056249 WO2022087407A1 (en) | 2020-10-23 | 2021-10-22 | Compositions and methods for vaccination against neisseria gonorrhoeae |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023004729A true MX2023004729A (es) | 2023-06-29 |
Family
ID=81290088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023004729A MX2023004729A (es) | 2020-10-23 | 2021-10-22 | Composiciones y metodos de vacunacion contra neisseria gonorrhoeae. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230256072A1 (es) |
EP (1) | EP4232158A1 (es) |
JP (1) | JP2023546665A (es) |
KR (1) | KR20230112625A (es) |
CN (1) | CN116670157A (es) |
AU (1) | AU2021364838A1 (es) |
CA (1) | CA3166272A1 (es) |
CL (1) | CL2023001142A1 (es) |
IL (1) | IL302286A (es) |
MX (1) | MX2023004729A (es) |
WO (1) | WO2022087407A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117535333B (zh) * | 2024-01-04 | 2024-04-23 | 南方医科大学皮肤病医院(广东省皮肤病医院、广东省皮肤性病防治中心、中国麻风防治研究中心) | 促进淋球菌外膜囊泡分泌的方法、淋球菌敲除株及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2289545T3 (en) * | 2000-01-17 | 2016-09-05 | Glaxosmithkline Biologicals Sa | Supplemented OMV vaccine against meningococcus |
GB0213622D0 (en) * | 2002-06-13 | 2002-07-24 | Glaxosmithkline Biolog Sa | Vaccine Corporation |
US7357932B2 (en) * | 2004-06-16 | 2008-04-15 | Center Of Disease Control Department Of Health | Surface protein of Neisseria bacteria |
TW201221642A (en) * | 2010-11-15 | 2012-06-01 | Nat Health Research Institutes | Method of producing lipidated polypeptides |
-
2021
- 2021-10-22 AU AU2021364838A patent/AU2021364838A1/en active Pending
- 2021-10-22 KR KR1020237017032A patent/KR20230112625A/ko unknown
- 2021-10-22 EP EP21883984.3A patent/EP4232158A1/en active Pending
- 2021-10-22 MX MX2023004729A patent/MX2023004729A/es unknown
- 2021-10-22 CN CN202180080544.1A patent/CN116670157A/zh active Pending
- 2021-10-22 JP JP2023524413A patent/JP2023546665A/ja active Pending
- 2021-10-22 WO PCT/US2021/056249 patent/WO2022087407A1/en active Application Filing
- 2021-10-22 CA CA3166272A patent/CA3166272A1/en active Pending
- 2021-10-22 IL IL302286A patent/IL302286A/en unknown
-
2023
- 2023-04-20 CL CL2023001142A patent/CL2023001142A1/es unknown
- 2023-04-21 US US18/305,164 patent/US20230256072A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230256072A1 (en) | 2023-08-17 |
AU2021364838A9 (en) | 2024-05-23 |
EP4232158A1 (en) | 2023-08-30 |
KR20230112625A (ko) | 2023-07-27 |
WO2022087407A1 (en) | 2022-04-28 |
CL2023001142A1 (es) | 2023-12-15 |
AU2021364838A1 (en) | 2023-06-08 |
IL302286A (en) | 2023-06-01 |
JP2023546665A (ja) | 2023-11-07 |
CN116670157A (zh) | 2023-08-29 |
CA3166272A1 (en) | 2022-04-28 |
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