MX2023002847A - Reacciones de compuestos radiactivos facilitadas por una fase solida. - Google Patents

Reacciones de compuestos radiactivos facilitadas por una fase solida.

Info

Publication number
MX2023002847A
MX2023002847A MX2023002847A MX2023002847A MX2023002847A MX 2023002847 A MX2023002847 A MX 2023002847A MX 2023002847 A MX2023002847 A MX 2023002847A MX 2023002847 A MX2023002847 A MX 2023002847A MX 2023002847 A MX2023002847 A MX 2023002847A
Authority
MX
Mexico
Prior art keywords
reactions
solid phase
radioactive compounds
facilitated
compounds facilitated
Prior art date
Application number
MX2023002847A
Other languages
English (en)
Inventor
Matthias Friebe
Navarro Laurent
Nicolas Verbrugge
Matthias D`Huyvetter
Vincent Tadino
Nicolas Maindron
Yoann Joyard
Original Assignee
Precirix N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Precirix N V filed Critical Precirix N V
Publication of MX2023002847A publication Critical patent/MX2023002847A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006Controlling or regulating processes
    • B01J19/0013Controlling the temperature of the process
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008Peptides; Proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049Controlling or regulating processes
    • B01J2219/00051Controlling the temperature
    • B01J2219/00074Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00087Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
    • B01J2219/00092Tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049Controlling or regulating processes
    • B01J2219/00051Controlling the temperature
    • B01J2219/0015Controlling the temperature by thermal insulation means
    • B01J2219/00155Controlling the temperature by thermal insulation means using insulating materials or refractories
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona un método para llevar a cabo reacciones químicas de compuestos radioactivos, y un dispositivo, sistema y método para calentamiento mejorado para reacciones químicas.
MX2023002847A 2020-09-11 2021-09-07 Reacciones de compuestos radiactivos facilitadas por una fase solida. MX2023002847A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20306019.9A EP3967674A1 (en) 2020-09-11 2020-09-11 Reactions of radioactive compounds facilitated by a solid phase
PCT/EP2021/074579 WO2022053459A1 (en) 2020-09-11 2021-09-07 Reactions of radioactive compounds facilitated by a solid phase

Publications (1)

Publication Number Publication Date
MX2023002847A true MX2023002847A (es) 2023-07-07

Family

ID=73854800

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023002847A MX2023002847A (es) 2020-09-11 2021-09-07 Reacciones de compuestos radiactivos facilitadas por una fase solida.

Country Status (10)

Country Link
US (1) US20230382855A1 (es)
EP (2) EP3967674A1 (es)
JP (1) JP2023541892A (es)
KR (1) KR20230088707A (es)
CN (1) CN116390899A (es)
AU (1) AU2021340192A1 (es)
CA (1) CA3192297A1 (es)
IL (1) IL301272A (es)
MX (1) MX2023002847A (es)
WO (1) WO2022053459A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3967674A1 (en) 2020-09-11 2022-03-16 Precirix N.V. Reactions of radioactive compounds facilitated by a solid phase

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1010280A3 (fr) 1996-05-02 1998-05-05 Coincidence S A Procede et dispositif de synthese de 2-[18f] fluoro-2-deoxy-d-glucose.
SE515339C2 (sv) 1999-12-16 2001-07-16 Propel Ab Användning av en värmbar matta för tillverkning av en ortos
EP1979079A4 (en) 2006-02-03 2012-11-28 Integenx Inc MICROFLUIDIC DEVICES
RU2468940C1 (ru) 2008-10-13 2012-12-10 ХВБ, ЭлЭлСи Узел бескаркасного подогреваемого стеклоочистителя и система, в которой он используется
US20140256970A1 (en) 2011-09-30 2014-09-11 Ge Healthcare Limited Reactor for multi-step radiochemistry
CN104470547B (zh) * 2012-05-24 2018-01-26 未来化学株式会社 利用筒状物合成放射性药物的方法
EP2821383B1 (en) 2013-07-02 2017-08-30 Trasis S.A. Stabilization of radiosynthetic intermediates
US9408257B2 (en) 2013-12-20 2016-08-02 Tutco, Inc. Silicone band cable heater assembly, method of making and method of use
GB201504407D0 (en) 2015-03-16 2015-04-29 Ge Healthcare Ltd Radiosynthesiser add-on device
BR112018000672A2 (pt) * 2015-07-17 2018-09-18 Univ Brussel Vrije fragmentos de anticorpo radiomarcados para uso no tratamento de câncer
EP3967674A1 (en) 2020-09-11 2022-03-16 Precirix N.V. Reactions of radioactive compounds facilitated by a solid phase

Also Published As

Publication number Publication date
US20230382855A1 (en) 2023-11-30
WO2022053459A1 (en) 2022-03-17
CA3192297A1 (en) 2022-03-17
JP2023541892A (ja) 2023-10-04
CN116390899A (zh) 2023-07-04
AU2021340192A1 (en) 2023-05-25
IL301272A (en) 2023-05-01
EP4211099A1 (en) 2023-07-19
EP3967674A1 (en) 2022-03-16
KR20230088707A (ko) 2023-06-20

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