MX2023001649A - Derivados de amida hibrida de anfotericina b. - Google Patents

Derivados de amida hibrida de anfotericina b.

Info

Publication number
MX2023001649A
MX2023001649A MX2023001649A MX2023001649A MX2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A
Authority
MX
Mexico
Prior art keywords
amphotericin
amide derivatives
disclosed
salts
hybrid amide
Prior art date
Application number
MX2023001649A
Other languages
English (en)
Spanish (es)
Inventor
Arun Maji
Martin D Burke
Original Assignee
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois filed Critical Univ Illinois
Publication of MX2023001649A publication Critical patent/MX2023001649A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
MX2023001649A 2020-08-10 2021-08-09 Derivados de amida hibrida de anfotericina b. MX2023001649A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063063655P 2020-08-10 2020-08-10
US202163175771P 2021-04-16 2021-04-16
PCT/US2021/045205 WO2022035752A1 (en) 2020-08-10 2021-08-09 Hybrid amide derivatives of amphotericin b

Publications (1)

Publication Number Publication Date
MX2023001649A true MX2023001649A (es) 2023-04-24

Family

ID=80247344

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023001649A MX2023001649A (es) 2020-08-10 2021-08-09 Derivados de amida hibrida de anfotericina b.

Country Status (12)

Country Link
US (1) US20230357303A1 (https=)
EP (2) EP4696379A3 (https=)
JP (1) JP7656359B2 (https=)
KR (1) KR20230061405A (https=)
CN (1) CN116323632B (https=)
AU (1) AU2021325676A1 (https=)
CA (1) CA3190997A1 (https=)
ES (1) ES3061451T3 (https=)
IL (1) IL300441A (https=)
MX (1) MX2023001649A (https=)
PT (1) PT4192248T (https=)
WO (1) WO2022035752A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122086B1 (en) * 1979-04-09 1982-06-30 Politechnika Gdanska Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh
AU643141B2 (en) 1991-03-15 1993-11-04 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
US6664241B2 (en) * 2000-05-31 2003-12-16 Micrologix Biotech Inc. Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
JP6543272B2 (ja) * 2014-05-16 2019-07-10 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイThe Board Of Trustees Of The University Of Illinois 低減された毒性を有するアンホテリシンb誘導体
TWI702223B (zh) * 2014-06-12 2020-08-21 日商塩野義製藥股份有限公司 多烯巨環內酯衍生物
CA3021061C (en) * 2015-04-15 2023-10-24 Martin D. Burke Derivatives of amphotericin b
JP7477177B2 (ja) * 2018-09-07 2024-05-01 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ 毒性が低減されたハイブリッドアムホテリシンb誘導体
EP4009985A4 (en) * 2019-08-08 2023-09-06 The Board Of Trustees Of The University Of Illinois HYBRID AMIDE DERIVATIVES OF AMPHOTERICIN B

Also Published As

Publication number Publication date
ES3061451T3 (en) 2026-04-01
JP2023537921A (ja) 2023-09-06
EP4192248B1 (en) 2025-12-03
JP7656359B2 (ja) 2025-04-03
IL300441A (en) 2023-04-01
WO2022035752A1 (en) 2022-02-17
EP4696379A3 (en) 2026-02-25
EP4192248A1 (en) 2023-06-14
CA3190997A1 (en) 2022-02-17
CN116323632B (zh) 2024-12-31
EP4192248A4 (en) 2024-12-04
AU2021325676A1 (en) 2023-03-30
US20230357303A1 (en) 2023-11-09
KR20230061405A (ko) 2023-05-08
CN116323632A (zh) 2023-06-23
EP4696379A2 (en) 2026-02-18
PT4192248T (pt) 2026-02-11

Similar Documents

Publication Publication Date Title
PH12021551256A1 (en) Pantetheine derivatives and uses thereof
WO2021262826A3 (en) 1'-cyano nucleoside analogs and uses thereof
MX2020013373A (es) Compuestos de naftiridinona utiles como activadores de celulas t.
WO2021147236A9 (zh) 取代氨基丙酸酯类化合物在治疗SARS-CoV-2感染中的应用
MX2022001678A (es) Derivados amidas hibridas de anfotericina b.
BRPI0409198A (pt) derivados quinolin-2-ona para o tratamento de doenças de vias aéreas
ATE307810T1 (de) Imidazol-2-carbonsäureamid derivate als raf- kinase-inhibitoren
WO2015157559A3 (en) 10',11'-modified saxitoxins useful for the treatment of pain
MXPA04005156A (es) Antagonistas del receptor de adenosina a2a.
AU2020231934A8 (en) Compounds useful in HIV therapy
EA200970535A1 (ru) Антибактериальные производные хинолина
MX2022015886A (es) Derivados de amidopirimidona.
GEAP202516634A (en) Heteroaryl compounds for the treatment of pain
MX2025011346A (es) Compuestos de quinolinona amida y usos de los mismos
PH12019500618A1 (en) Pharmaceutical composition and method for treatment of non-alcoholic fatty liver disease
EA201992090A1 (ru) ДЕЙТЕРИРОВАННЫЕ СОЕДИНЕНИЯ ИМИДАЗО[4,5-c]ХИНОЛИН-2-ОНА И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ РАКА
MX2022003845A (es) Tratamientos cognitivos medicinales.
PH12020552186A1 (en) Cyanotriazole compounds and uses thereof
UA83832C2 (ru) Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и их применение
MX2009007040A (es) Derivados de mononitrato de isosorbida para el tratamiento de hipertension ocular.
MX2023009166A (es) Derivados de quinoxalina y sus usos.
MX2023001649A (es) Derivados de amida hibrida de anfotericina b.
EA200970536A1 (ru) Антибактериальные хинолиновые производные
MX2024006176A (es) Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno.
CR20230331A (es) Derivados de pirazolamida