MX2023001649A - Derivados de amida hibrida de anfotericina b. - Google Patents

Derivados de amida hibrida de anfotericina b.

Info

Publication number
MX2023001649A
MX2023001649A MX2023001649A MX2023001649A MX2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A MX 2023001649 A MX2023001649 A MX 2023001649A
Authority
MX
Mexico
Prior art keywords
amphotericin
amide derivatives
disclosed
salts
hybrid amide
Prior art date
Application number
MX2023001649A
Other languages
English (en)
Spanish (es)
Inventor
Arun Maji
Martin D Burke
Original Assignee
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois filed Critical Univ Illinois
Publication of MX2023001649A publication Critical patent/MX2023001649A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
MX2023001649A 2020-08-10 2021-08-09 Derivados de amida hibrida de anfotericina b. MX2023001649A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063063655P 2020-08-10 2020-08-10
US202163175771P 2021-04-16 2021-04-16
PCT/US2021/045205 WO2022035752A1 (en) 2020-08-10 2021-08-09 Hybrid amide derivatives of amphotericin b

Publications (1)

Publication Number Publication Date
MX2023001649A true MX2023001649A (es) 2023-04-24

Family

ID=80247344

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2023001649A MX2023001649A (es) 2020-08-10 2021-08-09 Derivados de amida hibrida de anfotericina b.

Country Status (12)

Country Link
US (1) US20230357303A1 (https=)
EP (2) EP4192248B1 (https=)
JP (1) JP7656359B2 (https=)
KR (1) KR20230061405A (https=)
CN (1) CN116323632B (https=)
AU (1) AU2021325676A1 (https=)
CA (1) CA3190997A1 (https=)
ES (1) ES3061451T3 (https=)
IL (1) IL300441A (https=)
MX (1) MX2023001649A (https=)
PT (1) PT4192248T (https=)
WO (1) WO2022035752A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122086B1 (en) * 1979-04-09 1982-06-30 Politechnika Gdanska Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh
JP3507486B2 (ja) 1991-03-15 2004-03-15 アムジエン・インコーポレーテツド 顆粒球コロニー刺激因子の肺内投与
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
US6664241B2 (en) * 2000-05-31 2003-12-16 Micrologix Biotech Inc. Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
ES2749927T3 (es) * 2014-05-16 2020-03-24 Univ Illinois Derivado de anfotericina b con toxicidad reducida
MA39568A1 (fr) * 2014-06-12 2017-09-29 Shionogi & Co Dérivé de macrolide de polyène
JP7240811B2 (ja) * 2015-04-15 2023-03-16 スファンガ セラピューティクス インコーポレイテッド アムホテリシンｂの誘導体
CA3111565A1 (en) * 2018-09-07 2020-03-12 The Board Of Trustees Of The University Of Illinois Hybrid amphotericin b derivatives with reduced toxicity
EP4009985A4 (en) * 2019-08-08 2023-09-06 The Board Of Trustees Of The University Of Illinois HYBRID AMIDE DERIVATIVES OF AMPHOTERICIN B

Also Published As

Publication number Publication date
EP4696379A3 (en) 2026-02-25
PT4192248T (pt) 2026-02-11
KR20230061405A (ko) 2023-05-08
WO2022035752A1 (en) 2022-02-17
JP7656359B2 (ja) 2025-04-03
EP4696379A2 (en) 2026-02-18
EP4192248B1 (en) 2025-12-03
IL300441A (en) 2023-04-01
CN116323632A (zh) 2023-06-23
US20230357303A1 (en) 2023-11-09
JP2023537921A (ja) 2023-09-06
AU2021325676A1 (en) 2023-03-30
CN116323632B (zh) 2024-12-31
EP4192248A1 (en) 2023-06-14
EP4192248A4 (en) 2024-12-04
ES3061451T3 (en) 2026-04-01
CA3190997A1 (en) 2022-02-17

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