IL300441A - Hybrid amide derivatives of amphotericin b - Google Patents
Hybrid amide derivatives of amphotericin bInfo
- Publication number
- IL300441A IL300441A IL300441A IL30044123A IL300441A IL 300441 A IL300441 A IL 300441A IL 300441 A IL300441 A IL 300441A IL 30044123 A IL30044123 A IL 30044123A IL 300441 A IL300441 A IL 300441A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- amb
- pct
- compounds
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063063655P | 2020-08-10 | 2020-08-10 | |
| US202163175771P | 2021-04-16 | 2021-04-16 | |
| PCT/US2021/045205 WO2022035752A1 (en) | 2020-08-10 | 2021-08-09 | Hybrid amide derivatives of amphotericin b |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL300441A true IL300441A (en) | 2023-04-01 |
Family
ID=80247344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL300441A IL300441A (en) | 2020-08-10 | 2021-08-09 | Hybrid amide derivatives of amphotericin b |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230357303A1 (https=) |
| EP (2) | EP4192248B1 (https=) |
| JP (1) | JP7656359B2 (https=) |
| KR (1) | KR20230061405A (https=) |
| CN (1) | CN116323632B (https=) |
| AU (1) | AU2021325676A1 (https=) |
| CA (1) | CA3190997A1 (https=) |
| ES (1) | ES3061451T3 (https=) |
| IL (1) | IL300441A (https=) |
| MX (1) | MX2023001649A (https=) |
| PT (1) | PT4192248T (https=) |
| WO (1) | WO2022035752A1 (https=) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL122086B1 (en) * | 1979-04-09 | 1982-06-30 | Politechnika Gdanska | Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh |
| JP3507486B2 (ja) | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
| US6664241B2 (en) * | 2000-05-31 | 2003-12-16 | Micrologix Biotech Inc. | Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof |
| ES2749927T3 (es) * | 2014-05-16 | 2020-03-24 | Univ Illinois | Derivado de anfotericina b con toxicidad reducida |
| MA39568A1 (fr) * | 2014-06-12 | 2017-09-29 | Shionogi & Co | Dérivé de macrolide de polyène |
| JP7240811B2 (ja) * | 2015-04-15 | 2023-03-16 | スファンガ セラピューティクス インコーポレイテッド | アムホテリシンｂの誘導体 |
| CA3111565A1 (en) * | 2018-09-07 | 2020-03-12 | The Board Of Trustees Of The University Of Illinois | Hybrid amphotericin b derivatives with reduced toxicity |
| EP4009985A4 (en) * | 2019-08-08 | 2023-09-06 | The Board Of Trustees Of The University Of Illinois | HYBRID AMIDE DERIVATIVES OF AMPHOTERICIN B |
-
2021
- 2021-08-09 AU AU2021325676A patent/AU2021325676A1/en active Pending
- 2021-08-09 US US18/020,119 patent/US20230357303A1/en active Pending
- 2021-08-09 CA CA3190997A patent/CA3190997A1/en active Pending
- 2021-08-09 EP EP21856507.5A patent/EP4192248B1/en active Active
- 2021-08-09 JP JP2023508551A patent/JP7656359B2/ja active Active
- 2021-08-09 IL IL300441A patent/IL300441A/en unknown
- 2021-08-09 PT PT218565075T patent/PT4192248T/pt unknown
- 2021-08-09 CN CN202180066848.2A patent/CN116323632B/zh active Active
- 2021-08-09 MX MX2023001649A patent/MX2023001649A/es unknown
- 2021-08-09 WO PCT/US2021/045205 patent/WO2022035752A1/en not_active Ceased
- 2021-08-09 KR KR1020237008208A patent/KR20230061405A/ko active Pending
- 2021-08-09 ES ES21856507T patent/ES3061451T3/es active Active
- 2021-08-09 EP EP25211492.1A patent/EP4696379A3/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4696379A3 (en) | 2026-02-25 |
| PT4192248T (pt) | 2026-02-11 |
| KR20230061405A (ko) | 2023-05-08 |
| WO2022035752A1 (en) | 2022-02-17 |
| JP7656359B2 (ja) | 2025-04-03 |
| EP4696379A2 (en) | 2026-02-18 |
| EP4192248B1 (en) | 2025-12-03 |
| CN116323632A (zh) | 2023-06-23 |
| US20230357303A1 (en) | 2023-11-09 |
| JP2023537921A (ja) | 2023-09-06 |
| AU2021325676A1 (en) | 2023-03-30 |
| CN116323632B (zh) | 2024-12-31 |
| EP4192248A1 (en) | 2023-06-14 |
| EP4192248A4 (en) | 2024-12-04 |
| ES3061451T3 (en) | 2026-04-01 |
| MX2023001649A (es) | 2023-04-24 |
| CA3190997A1 (en) | 2022-02-17 |
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