MX2022015250A - Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn. - Google Patents

Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.

Info

Publication number
MX2022015250A
MX2022015250A MX2022015250A MX2022015250A MX2022015250A MX 2022015250 A MX2022015250 A MX 2022015250A MX 2022015250 A MX2022015250 A MX 2022015250A MX 2022015250 A MX2022015250 A MX 2022015250A MX 2022015250 A MX2022015250 A MX 2022015250A
Authority
MX
Mexico
Prior art keywords
crohn
disease
treatment
antibody
antibodies
Prior art date
Application number
MX2022015250A
Other languages
English (en)
Inventor
Annette Bettina Galler
Steven John Padula
Bojan LALOVIC
Sudha Visvanathan
Paul Scholl
Wulf Otto Boecher
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2022015250A publication Critical patent/MX2022015250A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se refiere generalmente a métodos para el tratamiento de enfermedades relacionadas con IL-23, en particular, enfermedades inflamatorias, tales como la enfermedad de Crohn, que utilizan anticuerpos anti-IL-23ª.
MX2022015250A 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn. MX2022015250A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562220410P 2015-09-18 2015-09-18
US201562235654P 2015-10-01 2015-10-01
US201662295643P 2016-02-16 2016-02-16
US201662328863P 2016-04-28 2016-04-28
US201662335242P 2016-05-12 2016-05-12
US201662339192P 2016-05-20 2016-05-20

Publications (1)

Publication Number Publication Date
MX2022015250A true MX2022015250A (es) 2023-01-11

Family

ID=57003593

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2018003174A MX2018003174A (es) 2015-09-18 2016-09-15 Metodos para tratar enfermedades inflamatorias.
MX2022015248A MX2022015248A (es) 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.
MX2022015250A MX2022015250A (es) 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2018003174A MX2018003174A (es) 2015-09-18 2016-09-15 Metodos para tratar enfermedades inflamatorias.
MX2022015248A MX2022015248A (es) 2015-09-18 2018-03-14 Un anticuerpo anti-il-23a para usarse en el tratamiento de la enfermedad de crohn.

Country Status (16)

Country Link
US (1) US20170081402A1 (es)
EP (1) EP3350221A1 (es)
JP (7) JP6668461B2 (es)
KR (2) KR20180053395A (es)
CN (1) CN108026168A (es)
AU (2) AU2016323152A1 (es)
BR (1) BR112018003526A2 (es)
CA (1) CA2996645A1 (es)
CL (1) CL2018000597A1 (es)
EA (1) EA201890747A1 (es)
HK (1) HK1252037A1 (es)
IL (2) IL302197A (es)
MX (3) MX2018003174A (es)
PH (2) PH12022550515A1 (es)
TW (2) TWI811716B (es)
WO (1) WO2017048901A1 (es)

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NZ700802A (en) 2012-05-03 2017-06-30 Boehringer Ingelheim Int Anti-il-23p19 antibodies
EP3708679A1 (en) 2014-07-24 2020-09-16 Boehringer Ingelheim International GmbH Biomarkers useful in the treatment of il-23a related diseases
IL321788A (en) 2015-02-04 2025-08-01 Boehringer Ingelheim Int Methods of treating inflammatory diseases
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EP3848390A1 (en) * 2016-10-14 2021-07-14 Boehringer Ingelheim International GmbH Methods of treating diseases
IL276896B2 (en) * 2018-03-05 2024-06-01 Janssen Biotech Inc Methods of treating crohn's disease with anti-il23 specific antibody
WO2019246312A1 (en) * 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
TW202515610A (zh) * 2019-04-22 2025-04-16 美商美國禮來大藥廠 治療克隆氏症(crohn's disease)的方法
US11780911B2 (en) 2019-05-23 2023-10-10 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha
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CN115768466A (zh) 2020-05-21 2023-03-07 詹森生物科技公司 用抗IL-23和TNFα抗体的联合疗法治疗炎性肠病的方法
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Also Published As

Publication number Publication date
IL302197A (en) 2023-06-01
JP2022088478A (ja) 2022-06-14
MX2022015248A (es) 2023-01-11
TWI811716B (zh) 2023-08-11
TWI733695B (zh) 2021-07-21
CL2018000597A1 (es) 2018-07-27
IL257561A (en) 2018-04-30
JP2024096863A (ja) 2024-07-17
JP2026048776A (ja) 2026-03-17
KR20180053395A (ko) 2018-05-21
TW202138008A (zh) 2021-10-16
AU2016323152A1 (en) 2018-02-22
JP2020100643A (ja) 2020-07-02
PH12018500578A1 (en) 2018-09-10
JP2022046624A (ja) 2022-03-23
EP3350221A1 (en) 2018-07-25
NZ739608A (en) 2025-05-30
AU2023203530A1 (en) 2023-07-06
TW201722474A (zh) 2017-07-01
HK1252037A1 (zh) 2019-05-10
WO2017048901A1 (en) 2017-03-23
JP7000476B2 (ja) 2022-02-04
JP7477492B2 (ja) 2024-05-01
BR112018003526A2 (pt) 2018-09-25
JP2020100644A (ja) 2020-07-02
PH12022550515A1 (en) 2023-02-27
CA2996645A1 (en) 2017-03-23
US20170081402A1 (en) 2017-03-23
JP6668461B2 (ja) 2020-03-18
NZ780210A (en) 2025-05-30
MX2018003174A (es) 2018-05-17
JP2018527380A (ja) 2018-09-20
EA201890747A1 (ru) 2018-10-31
CN108026168A (zh) 2018-05-11
KR20240170593A (ko) 2024-12-03

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