MX2022011982A - Epitopos de celulas t reguladoras. - Google Patents
Epitopos de celulas t reguladoras.Info
- Publication number
- MX2022011982A MX2022011982A MX2022011982A MX2022011982A MX2022011982A MX 2022011982 A MX2022011982 A MX 2022011982A MX 2022011982 A MX2022011982 A MX 2022011982A MX 2022011982 A MX2022011982 A MX 2022011982A MX 2022011982 A MX2022011982 A MX 2022011982A
- Authority
- MX
- Mexico
- Prior art keywords
- regulatory
- cell epitopes
- terminus
- polypeptide
- seq
- Prior art date
Links
- 210000003289 regulatory T cell Anatomy 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Abstract
La presente invención se refiere a composiciones que comprenden epítopos de células T reguladoras, en donde dichos epítopos comprenden un polipéptido que comprende por lo menos una porción de las SEQ ID NO: 1-124 (y/o fragmentos y variantes de los mismos), y opcionalmente de 1 a 12 aminoácidos adicionales distribuidos en cualquier proporción en el N-terminal y/o C-terminal del polipéptido de SEQ ID NO: 1-124, así como a los métodos de producción y el uso de las mismas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063000630P | 2020-03-27 | 2020-03-27 | |
US202063077253P | 2020-09-11 | 2020-09-11 | |
PCT/US2021/024352 WO2021195492A1 (en) | 2020-03-27 | 2021-03-26 | Regulatory t cell epitopes |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022011982A true MX2022011982A (es) | 2022-12-15 |
Family
ID=77890731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022011982A MX2022011982A (es) | 2020-03-27 | 2021-03-26 | Epitopos de celulas t reguladoras. |
Country Status (8)
Country | Link |
---|---|
US (1) | US11911414B2 (es) |
EP (1) | EP4126901A4 (es) |
JP (1) | JP2023520990A (es) |
KR (1) | KR20220160640A (es) |
AU (1) | AU2021242326A1 (es) |
CA (1) | CA3172976A1 (es) |
MX (1) | MX2022011982A (es) |
WO (1) | WO2021195492A1 (es) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2006122946A (ru) * | 2003-11-28 | 2008-01-10 | Астразенека Аб (Se) | Антитела |
EP2450366A1 (en) * | 2007-01-30 | 2012-05-09 | Epivax, Inc. | Regulatory t cell epitopes, compositions and uses thereof |
AU2018346681B2 (en) * | 2017-10-05 | 2024-02-22 | Epivax, Inc. | Regulatory T cell epitopes |
BR112020022897A2 (pt) * | 2018-05-23 | 2021-02-23 | Pfizer Inc. | anticorpos específicos para cd3 e usos dos mesmos |
-
2021
- 2021-03-26 MX MX2022011982A patent/MX2022011982A/es unknown
- 2021-03-26 CA CA3172976A patent/CA3172976A1/en active Pending
- 2021-03-26 WO PCT/US2021/024352 patent/WO2021195492A1/en active Application Filing
- 2021-03-26 US US17/214,061 patent/US11911414B2/en active Active
- 2021-03-26 KR KR1020227037494A patent/KR20220160640A/ko active Search and Examination
- 2021-03-26 AU AU2021242326A patent/AU2021242326A1/en active Pending
- 2021-03-26 EP EP21775536.2A patent/EP4126901A4/en active Pending
- 2021-03-26 JP JP2022558198A patent/JP2023520990A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2021195492A1 (en) | 2021-09-30 |
JP2023520990A (ja) | 2023-05-23 |
KR20220160640A (ko) | 2022-12-06 |
AU2021242326A1 (en) | 2022-10-20 |
EP4126901A1 (en) | 2023-02-08 |
CA3172976A1 (en) | 2021-09-30 |
EP4126901A4 (en) | 2024-04-10 |
US11911414B2 (en) | 2024-02-27 |
US20210308182A1 (en) | 2021-10-07 |
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