MX2022011832A - Compuestos terpenofenolicos y su uso. - Google Patents

Compuestos terpenofenolicos y su uso.

Info

Publication number
MX2022011832A
MX2022011832A MX2022011832A MX2022011832A MX2022011832A MX 2022011832 A MX2022011832 A MX 2022011832A MX 2022011832 A MX2022011832 A MX 2022011832A MX 2022011832 A MX2022011832 A MX 2022011832A MX 2022011832 A MX2022011832 A MX 2022011832A
Authority
MX
Mexico
Prior art keywords
compounds
cbd
ene
tetrahydro
prop
Prior art date
Application number
MX2022011832A
Other languages
English (en)
Spanish (es)
Inventor
Colin George Stott
Charles R Heap
Ramamoorthy Gurusankar
Original Assignee
Phytotherapeutix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phytotherapeutix Ltd filed Critical Phytotherapeutix Ltd
Publication of MX2022011832A publication Critical patent/MX2022011832A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/23Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/32Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions without formation of -OH groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/38Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/003Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by hydrogenation of an unsaturated part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/11Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
    • C07C37/14Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms by addition reactions, i.e. reactions involving at least one carbon-to-carbon unsaturated bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/15Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2022011832A 2020-03-31 2021-03-31 Compuestos terpenofenolicos y su uso. MX2022011832A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063003270P 2020-03-31 2020-03-31
PCT/GB2021/050812 WO2021198692A1 (en) 2020-03-31 2021-03-31 Terpenophenolic compounds and their use

Publications (1)

Publication Number Publication Date
MX2022011832A true MX2022011832A (es) 2023-03-03

Family

ID=75426633

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022011832A MX2022011832A (es) 2020-03-31 2021-03-31 Compuestos terpenofenolicos y su uso.

Country Status (12)

Country Link
US (2) US12552733B2 (https=)
EP (1) EP4126800A1 (https=)
JP (1) JP7714571B2 (https=)
KR (1) KR20230121960A (https=)
CN (1) CN116194431B (https=)
AU (1) AU2021248627A1 (https=)
BR (1) BR112022019616A2 (https=)
CA (1) CA3177186A1 (https=)
GB (2) GB2609814B (https=)
IL (1) IL296861A (https=)
MX (1) MX2022011832A (https=)
WO (1) WO2021198692A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3179235A1 (en) * 2019-05-23 2020-11-26 Kare Chemical Technologies Inc. Catalytic cannabinoid processes and precursors

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136839A (en) * 2000-06-16 2006-12-10 Yissum Res Dev Co Pharmaceutical compositions comprising cannabidiol derivatives, and processes for the preparation of same
CA2623723A1 (en) 2005-09-29 2007-04-12 Amr Technology, Inc. Process for production of delta-9-tetrahydrocannabinol
DK2176208T3 (en) * 2007-07-30 2015-04-27 Zynerba Pharmaceuticals Inc Prodrugs of cannabidiol, compositions containing prodrugs of cannabidiol and methods of use thereof
DE102009019322A1 (de) * 2009-04-30 2010-11-11 The Health Concept Gmbh Verfahren zur Herstellung von Synthetischen Cannabinoiden
TWI583374B (zh) * 2010-03-30 2017-05-21 Gw伐瑪有限公司 使用植物大麻素次大麻二酚(cbdv)來治療癲癇之用途
WO2014177593A1 (en) 2013-04-29 2014-11-06 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Amorfrutin analogs as ppargamma-modulators
US9526706B1 (en) 2015-06-16 2016-12-27 Hong Kong Baptist University Method of using dihydro-resveratrol for treating acute pancreatitis and associated pulmonary injury
US9738581B2 (en) * 2015-06-16 2017-08-22 Hong Kong Baptist University Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions
US10059683B2 (en) 2015-07-10 2018-08-28 Noramco, Inc. Process for the production of cannabidiol and delta-9-tetrahydrocannabinol
AU2017250303B2 (en) 2016-04-15 2019-09-26 Teewinot Technologies Limited Biosynthesis of cannabinoid prodrugs
JP2019523228A (ja) 2016-06-16 2019-08-22 ティーウィノット テクノロジーズ リミテッド カンナビノイドプロドラッグの製造のための方法、薬学的製剤、およびその使用
US10640482B2 (en) 2017-07-21 2020-05-05 University Of South Florida Synthesis of cannabinoids
SG11202001725SA (en) * 2017-09-01 2020-03-30 Pureform Global Inc Synthetic cannabidiol compositions and methods of making the same
JP2021535203A (ja) * 2018-08-20 2021-12-16 ベッソール ファルマ、エルエルシー 既知および新規カンナビノイドの適用
CA3179235A1 (en) * 2019-05-23 2020-11-26 Kare Chemical Technologies Inc. Catalytic cannabinoid processes and precursors
AU2020345656A1 (en) * 2019-09-09 2022-04-21 Kare Chemical Technologies Inc. Cannabinoid derivatives, precursors and uses
WO2021046640A1 (en) * 2019-09-10 2021-03-18 Kare Chemical Technologies Inc. Cannabinoid derivatives and precursors, and asymmetric synthesis for same

Also Published As

Publication number Publication date
GB2595355A (en) 2021-11-24
GB202215746D0 (en) 2022-12-07
US20230227390A1 (en) 2023-07-20
CN116194431B (zh) 2026-01-02
BR112022019616A2 (pt) 2022-12-06
KR20230121960A (ko) 2023-08-22
WO2021198692A1 (en) 2021-10-07
JP7714571B2 (ja) 2025-07-29
GB2609814A (en) 2023-02-15
US12552733B2 (en) 2026-02-17
CA3177186A1 (en) 2021-10-07
US20230225985A1 (en) 2023-07-20
AU2021248627A1 (en) 2022-12-01
GB202104690D0 (en) 2021-05-12
IL296861A (en) 2022-11-01
EP4126800A1 (en) 2023-02-08
GB2609814B (en) 2024-08-28
JP2023520794A (ja) 2023-05-19
CN116194431A (zh) 2023-05-30

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