MX2022010413A - Compuestos de pirrolopiridina e imidazopiridina antivirales. - Google Patents

Compuestos de pirrolopiridina e imidazopiridina antivirales.

Info

Publication number
MX2022010413A
MX2022010413A MX2022010413A MX2022010413A MX2022010413A MX 2022010413 A MX2022010413 A MX 2022010413A MX 2022010413 A MX2022010413 A MX 2022010413A MX 2022010413 A MX2022010413 A MX 2022010413A MX 2022010413 A MX2022010413 A MX 2022010413A
Authority
MX
Mexico
Prior art keywords
sup
pyrrolopyridine
imidazopyridine
antiviral compounds
compounds
Prior art date
Application number
MX2022010413A
Other languages
English (en)
Inventor
Nesya Goris
Eleonora Kiss
Robert Vrancken
Original Assignee
Univ Leuven Kath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leuven Kath filed Critical Univ Leuven Kath
Publication of MX2022010413A publication Critical patent/MX2022010413A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un compuesto de la fórmula (I) o un estereoisómero, o tautómero, (ver Fórmula) (I) en la cual A1, A2, R1 y R2, tienen el mismo significado que el definido en las reivindicaciones y la descripción. La presente invención también se refiere a composiciones, en particular farmacéuticas, que comprenden dichos compuestos, y a usos de dichos compuestos y composiciones para la prevención y/o tratamiento de una infección causada por pestivirus en un animal.
MX2022010413A 2020-02-24 2021-02-24 Compuestos de pirrolopiridina e imidazopiridina antivirales. MX2022010413A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20158958 2020-02-24
PCT/EP2021/054486 WO2021170600A1 (en) 2020-02-24 2021-02-24 Pyrrolopyridine and imidazopyridine antiviral compounds

Publications (1)

Publication Number Publication Date
MX2022010413A true MX2022010413A (es) 2022-09-07

Family

ID=69810569

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022010413A MX2022010413A (es) 2020-02-24 2021-02-24 Compuestos de pirrolopiridina e imidazopiridina antivirales.

Country Status (9)

Country Link
US (1) US20230130598A1 (es)
EP (1) EP4110777A1 (es)
JP (1) JP2023514443A (es)
CN (1) CN115175909A (es)
AR (1) AR121403A1 (es)
AU (1) AU2021225333A1 (es)
BR (1) BR112022016733A2 (es)
MX (1) MX2022010413A (es)
WO (1) WO2021170600A1 (es)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS2334B (is) 1992-09-08 2008-02-15 Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) Aspartyl próteasi hemjari af nýjum flokki súlfonamíða
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
WO1999033792A2 (en) 1997-12-24 1999-07-08 Vertex Pharmaceuticals Incorporated Prodrugs os aspartyl protease inhibitors
CN1110492C (zh) 1997-12-24 2003-06-04 沃泰克斯药物股份有限公司 天冬氨酰蛋白酶抑制剂的前药
AU2012199A (en) 1997-12-24 1999-07-19 Vertex Pharmaceuticals Incorporated Prodrugs of aspartyl protease inhibitors
US6436989B1 (en) 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
ES2381890T3 (es) * 2003-12-22 2012-06-01 K.U.Leuven Research & Development Compuesto de imidazo[4,5-c]piridina y métodos de tratamiento antiviral
SI1706403T1 (sl) * 2003-12-22 2012-08-31 Leuven K U Res & Dev Imidazo(4,5-c)piridin spojine in postopki antivirusnega zdravljenja
WO2007034277A1 (en) * 2005-09-19 2007-03-29 Pfizer Products Inc. Aryl substituted imidazo [4,5-c] pyridine compounds as c3a receptor antagonists
DK2094702T3 (en) * 2006-12-14 2015-12-07 Gilead Sciences Inc viral inhibitors

Also Published As

Publication number Publication date
BR112022016733A2 (pt) 2022-10-11
AU2021225333A1 (en) 2022-08-11
AR121403A1 (es) 2022-06-01
EP4110777A1 (en) 2023-01-04
CN115175909A (zh) 2022-10-11
JP2023514443A (ja) 2023-04-05
US20230130598A1 (en) 2023-04-27
WO2021170600A1 (en) 2021-09-02

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