BR112022016733A2 - Compostos antivirais de pirrolpiridina e imidazopiridina - Google Patents

Compostos antivirais de pirrolpiridina e imidazopiridina

Info

Publication number
BR112022016733A2
BR112022016733A2 BR112022016733A BR112022016733A BR112022016733A2 BR 112022016733 A2 BR112022016733 A2 BR 112022016733A2 BR 112022016733 A BR112022016733 A BR 112022016733A BR 112022016733 A BR112022016733 A BR 112022016733A BR 112022016733 A2 BR112022016733 A2 BR 112022016733A2
Authority
BR
Brazil
Prior art keywords
pyrrolpiridine
imidazopyridine
antiviral compounds
compounds
compositions
Prior art date
Application number
BR112022016733A
Other languages
English (en)
Inventor
Kiss Eleonora
Vrancken Robert
Goris Nesya
Original Assignee
Univ Leuven Kath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leuven Kath filed Critical Univ Leuven Kath
Publication of BR112022016733A2 publication Critical patent/BR112022016733A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPOSTOS ANTIVIRAIS DE PIRROLPIRIDINA E IMIDAZOPIRIDINA. A presente invenção se refere a um composto de fórmula (I) ou um estereoisômero, ou tautômero, (I) em que A1, A2, R1 e R2 têm o mesmo significado que o definido nas reivindicações e na descrição. A presente invenção também se refere a composições, em particular produtos farmacêuticos, compreendendo tais compostos, e aos usos de tais compostos e composições para a prevenção e/ou o tratamento de uma infecção causada por pestivírus em um animal.
BR112022016733A 2020-02-24 2021-02-24 Compostos antivirais de pirrolpiridina e imidazopiridina BR112022016733A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20158958 2020-02-24
PCT/EP2021/054486 WO2021170600A1 (en) 2020-02-24 2021-02-24 Pyrrolopyridine and imidazopyridine antiviral compounds

Publications (1)

Publication Number Publication Date
BR112022016733A2 true BR112022016733A2 (pt) 2022-10-11

Family

ID=69810569

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022016733A BR112022016733A2 (pt) 2020-02-24 2021-02-24 Compostos antivirais de pirrolpiridina e imidazopiridina

Country Status (9)

Country Link
US (1) US20230130598A1 (pt)
EP (1) EP4110777A1 (pt)
JP (1) JP2023514443A (pt)
CN (1) CN115175909A (pt)
AR (1) AR121403A1 (pt)
AU (1) AU2021225333A1 (pt)
BR (1) BR112022016733A2 (pt)
MX (1) MX2022010413A (pt)
WO (1) WO2021170600A1 (pt)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS2334B (is) 1992-09-08 2008-02-15 Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) Aspartyl próteasi hemjari af nýjum flokki súlfonamíða
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
AU2012199A (en) 1997-12-24 1999-07-19 Vertex Pharmaceuticals Incorporated Prodrugs of aspartyl protease inhibitors
AU2010299A (en) 1997-12-24 1999-07-19 Vertex Pharmaceuticals Incorporated Prodrugs os aspartyl protease inhibitors
BR9814484A (pt) 1997-12-24 2000-10-10 Vertex Pharma "pró-drogas de inibidores de aspartil protease"
US6436989B1 (en) 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US7648998B2 (en) * 2003-12-22 2010-01-19 K.U. Leuven Research & Development Imidazo 4,5-c pyridine compounds and methods of antiviral treatment
CN101538267B (zh) * 2003-12-22 2015-04-29 鲁汶天主教大学研究开发部 咪唑并[4,5-c]吡啶化合物和抗病毒治疗的方法
WO2007034277A1 (en) * 2005-09-19 2007-03-29 Pfizer Products Inc. Aryl substituted imidazo [4,5-c] pyridine compounds as c3a receptor antagonists
CA2672298C (en) * 2006-12-14 2015-02-03 K.U.Leuven Research & Development Fused pyridine compounds useful in the prophylaxis or treatment of viral infections

Also Published As

Publication number Publication date
AR121403A1 (es) 2022-06-01
JP2023514443A (ja) 2023-04-05
EP4110777A1 (en) 2023-01-04
MX2022010413A (es) 2022-09-07
AU2021225333A1 (en) 2022-08-11
US20230130598A1 (en) 2023-04-27
CN115175909A (zh) 2022-10-11
WO2021170600A1 (en) 2021-09-02

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