MX2022009572A - Composiciones de pirrolo[2,3-b]piridina-3-carboxamida y métodos para mejorar la pérdida de audición. - Google Patents
Composiciones de pirrolo[2,3-b]piridina-3-carboxamida y métodos para mejorar la pérdida de audición.Info
- Publication number
- MX2022009572A MX2022009572A MX2022009572A MX2022009572A MX2022009572A MX 2022009572 A MX2022009572 A MX 2022009572A MX 2022009572 A MX2022009572 A MX 2022009572A MX 2022009572 A MX2022009572 A MX 2022009572A MX 2022009572 A MX2022009572 A MX 2022009572A
- Authority
- MX
- Mexico
- Prior art keywords
- pyrrolo
- pyridine
- hearing loss
- methods
- ameliorating hearing
- Prior art date
Links
- 206010011878 Deafness Diseases 0.000 title abstract 2
- 230000010370 hearing loss Effects 0.000 title abstract 2
- 231100000888 hearing loss Toxicity 0.000 title abstract 2
- 208000016354 hearing loss disease Diseases 0.000 title abstract 2
- CQZYCDBHEULOFD-UHFFFAOYSA-N 1h-pyrrolo[2,3-b]pyridine-3-carboxamide Chemical compound C1=CC=C2C(C(=O)N)=CNC2=N1 CQZYCDBHEULOFD-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- -1 N-(3-Substituted thiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamides Chemical class 0.000 abstract 2
- 229930186657 Lat Natural products 0.000 abstract 1
- 108091000080 Phosphotransferase Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 102000020233 phosphotransferase Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062970425P | 2020-02-05 | 2020-02-05 | |
| PCT/US2021/016848 WO2021158936A1 (en) | 2020-02-05 | 2021-02-05 | Pyrrolo [2,3-b]pyridine-3-carboxamide compositions and methods for ameliorating hearing loss |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022009572A true MX2022009572A (es) | 2022-12-13 |
Family
ID=77199407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022009572A MX2022009572A (es) | 2020-02-05 | 2021-02-05 | Composiciones de pirrolo[2,3-b]piridina-3-carboxamida y métodos para mejorar la pérdida de audición. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4100008B1 (https=) |
| JP (1) | JP7678595B2 (https=) |
| CN (1) | CN115515579B (https=) |
| AU (1) | AU2021215925B2 (https=) |
| CA (1) | CA3170121A1 (https=) |
| ES (1) | ES3025983T3 (https=) |
| MX (1) | MX2022009572A (https=) |
| WO (1) | WO2021158936A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023015156A1 (en) * | 2021-08-02 | 2023-02-09 | Hudspeth A James | Pyrrolopyridine-3- and 4-carboxamide compositions and methods for cellular proliferation |
| WO2024211621A1 (en) * | 2023-04-04 | 2024-10-10 | Children's Hospital Los Angeles | Lats kinase inhibitor to treat retinal degeneration |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2888848B1 (fr) * | 2005-07-22 | 2007-09-28 | Sanofi Aventis Sa | Derives de n-(arylalkyl)-1h-pyrrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique |
| WO2007067537A1 (en) * | 2005-12-07 | 2007-06-14 | Osi Pharmaceuticals, Inc. | Pyrrolopyridine kinase inhibiting compounds |
| PE20121126A1 (es) * | 2006-12-21 | 2012-08-24 | Plexxikon Inc | Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa |
| TWI667233B (zh) * | 2013-12-19 | 2019-08-01 | 德商拜耳製藥公司 | 新穎吲唑羧醯胺，其製備方法、含彼等之醫藥製劑及其製造醫藥之用途 |
| GB201602854D0 (en) * | 2016-02-18 | 2016-04-06 | Mission Therapeutics Ltd | Novel compounds |
| JOP20190257A1 (ar) | 2017-04-28 | 2019-10-28 | Novartis Ag | مركبات أريل غير متجانسة ثنائية الحلقة مندمجة 6-6 واستخدامها كمثبطات lats |
-
2021
- 2021-02-05 CA CA3170121A patent/CA3170121A1/en active Pending
- 2021-02-05 WO PCT/US2021/016848 patent/WO2021158936A1/en not_active Ceased
- 2021-02-05 AU AU2021215925A patent/AU2021215925B2/en active Active
- 2021-02-05 MX MX2022009572A patent/MX2022009572A/es unknown
- 2021-02-05 CN CN202180019399.6A patent/CN115515579B/zh active Active
- 2021-02-05 ES ES21750999T patent/ES3025983T3/es active Active
- 2021-02-05 JP JP2022548109A patent/JP7678595B2/ja active Active
- 2021-02-05 EP EP21750999.1A patent/EP4100008B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20230137893A1 (en) | 2023-05-04 |
| WO2021158936A1 (en) | 2021-08-12 |
| AU2021215925A1 (en) | 2022-09-08 |
| EP4100008B1 (en) | 2025-04-02 |
| JP7678595B2 (ja) | 2025-05-16 |
| CA3170121A1 (en) | 2021-08-12 |
| EP4100008A4 (en) | 2024-02-07 |
| JP2023512823A (ja) | 2023-03-29 |
| AU2021215925B2 (en) | 2026-04-09 |
| EP4100008A1 (en) | 2022-12-14 |
| ES3025983T3 (en) | 2025-06-10 |
| CN115515579A (zh) | 2022-12-23 |
| CN115515579B (zh) | 2025-09-30 |
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