MX2022008727A - Factor de crecimiento derivado de mieloide para su uso en el tratamiento o la prevencion de fibrosis, hipertrofia o insuficiencia cardiaca. - Google Patents

Factor de crecimiento derivado de mieloide para su uso en el tratamiento o la prevencion de fibrosis, hipertrofia o insuficiencia cardiaca.

Info

Publication number
MX2022008727A
MX2022008727A MX2022008727A MX2022008727A MX2022008727A MX 2022008727 A MX2022008727 A MX 2022008727A MX 2022008727 A MX2022008727 A MX 2022008727A MX 2022008727 A MX2022008727 A MX 2022008727A MX 2022008727 A MX2022008727 A MX 2022008727A
Authority
MX
Mexico
Prior art keywords
treating
hypertrophy
heart failure
myeloid
growth factor
Prior art date
Application number
MX2022008727A
Other languages
English (en)
Spanish (es)
Inventor
Kai Christoph Wollert
Mortimer Korf-Klingebiel
Marc R Reboll
Anton Pekcec
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2022008727A publication Critical patent/MX2022008727A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MX2022008727A 2020-01-21 2021-01-19 Factor de crecimiento derivado de mieloide para su uso en el tratamiento o la prevencion de fibrosis, hipertrofia o insuficiencia cardiaca. MX2022008727A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20153008 2020-01-21
PCT/EP2021/051079 WO2021148411A1 (en) 2020-01-21 2021-01-19 Myeloid-derived growth factor for use in treating or preventing fibrosis, hypertrophy or heart failure

Publications (1)

Publication Number Publication Date
MX2022008727A true MX2022008727A (es) 2022-10-07

Family

ID=69187588

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022008727A MX2022008727A (es) 2020-01-21 2021-01-19 Factor de crecimiento derivado de mieloide para su uso en el tratamiento o la prevencion de fibrosis, hipertrofia o insuficiencia cardiaca.

Country Status (12)

Country Link
US (1) US20230059560A1 (https=)
EP (1) EP4093750A1 (https=)
JP (1) JP7777532B2 (https=)
KR (1) KR20220131262A (https=)
CN (1) CN115698048A (https=)
AU (1) AU2021211874A1 (https=)
BR (1) BR112022014272A2 (https=)
CA (2) CA3164500A1 (https=)
MX (1) MX2022008727A (https=)
PH (1) PH12022551792A1 (https=)
TW (1) TW202142254A (https=)
WO (1) WO2021148411A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11980654B2 (en) 2020-09-22 2024-05-14 Wisconsin Alumni Research Foundation Method to inhibit neutrophil recruitment to damaged tissue using myeloid-derived growth factor
JP2024501821A (ja) 2020-12-23 2024-01-16 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 心臓組織細胞に対する特異性を有するウイルスカプシドタンパク質
CN115820829B (zh) * 2022-03-22 2026-04-17 中国人民解放军军事科学院军事医学研究院 Mydgf在防治记忆损伤及其相关疾病中的应用
CA3258215A1 (en) 2022-06-03 2023-12-07 Boehringer Ingelheim International Gmbh RECOMBINANT EXPRESSION OF THE MYELOID-DERIVED GROWTH FACTOR
CN120112304A (zh) 2022-09-08 2025-06-06 勃林格殷格翰国际有限公司 用于治疗心源性休克的髓源性生长因子
EP4480490A1 (en) * 2023-06-23 2024-12-25 Medizinische Hochschule Hannover Brick1 for use in treating myocardial diseases
WO2025073372A1 (en) 2023-10-05 2025-04-10 Boehringer Ingelheim International Gmbh Recombinant expression of myeloid-derived growth factor
WO2025120204A1 (en) 2023-12-06 2025-06-12 Boehringer Ingelheim International Gmbh Novel formulation comprising myeloid-derived growth factor

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0173552B1 (en) 1984-08-24 1991-10-09 The Upjohn Company Recombinant dna compounds and the expression of polypeptides such as tpa
WO1997047358A1 (en) 1996-06-11 1997-12-18 Merck & Co., Inc. Synthetic hepatitis c genes
JP2001506484A (ja) 1996-09-13 2001-05-22 財団法人相模中央化学研究所 分泌シグナル配列を有するヒト蛋白質およびそれをコードするdna
AU4220797A (en) * 1996-09-13 1998-04-02 Protegene Inc. Human proteins having secretory signal sequences and DNAs encoding these prot eins
EP1578367A4 (en) 2002-11-01 2012-05-02 Genentech Inc COMPOSITIONS AND METHODS FOR THE TREATMENT OF IMMUNE DISEASES
WO2004069173A2 (en) 2003-01-31 2004-08-19 The Trustees Of The University Of Pennsylvania Methods for modulating an inflammatory response
US20080004232A1 (en) 2006-05-09 2008-01-03 John Wilkins Characterization of c19orf10, a Novel Synovial Protein
EP2130547A1 (en) 2008-06-06 2009-12-09 Giuliani International Limited IL-25 for use in the treatment of inflammatory diseases
EP3747457A3 (en) 2013-01-17 2021-03-03 Medizinische Hochschule Hannover Factor 1 protein, factor 2 protein and inhibitors thereof for use in treating or preventing diseases
KR20250133994A (ko) * 2018-05-09 2025-09-09 케로스 테라퓨틱스, 인크. 액티빈 수용체 유형 iia 변이체 및 그의 사용 방법
WO2020176732A1 (en) * 2019-02-27 2020-09-03 Icahn School Of Medicine At Mount Sinai TREATMENT OF PULMONARY FIBROSIS WITH SERCA2a GENE THERAPY

Also Published As

Publication number Publication date
JP2023511358A (ja) 2023-03-17
TW202142254A (zh) 2021-11-16
EP4093750A1 (en) 2022-11-30
CA3164500A1 (en) 2021-07-29
WO2021148411A1 (en) 2021-07-29
JP7777532B2 (ja) 2025-11-28
BR112022014272A2 (pt) 2022-09-20
AU2021211874A1 (en) 2022-08-25
CA3223879A1 (en) 2021-07-29
CN115698048A (zh) 2023-02-03
PH12022551792A1 (en) 2023-09-18
KR20220131262A (ko) 2022-09-27
US20230059560A1 (en) 2023-02-23

Similar Documents

Publication Publication Date Title
PH12022551792A1 (en) Myeloid-derived growth factor for use in treating or preventing fibrosis, hypertrophy or heart failure
MX2022005236A (es) Composiciones y metodos para el tratamiento de la perdida auditiva neurosensorial mediante el uso de sistemas de vectores duales de otoferlina.
PH12020551957A1 (en) Codon-optimized acid alpha-glucosidase expression cassettes and methods of using same
MX2016005101A (es) Factor de crecimiento de fibroblastos (fgf) 1 mutado y procedimientos de uso.
MX2020006424A (es) Polipéptidos de dominio de unión a células de toxina botulínica y métodos de uso para el rejuvenecimiento de la piel.
WO2016172156A3 (en) Fibroblast growth factor (fgf) 1 mutants and methods of use to reduce blood glucose
ATE352626T1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
WO2016172153A3 (en) Fibroblast growth factor (fgf) 1 with mutation in the heparin binding domain and methods of use to reduce blood glucose
NZ595497A (en) Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
DK1513937T3 (da) Fremgangsmåde til den samtidige produktion af multiple proteiner; vektorer og celler til anvendelse derved
DK1474507T3 (da) Fremgangsmåder og materialer til produktion af organiske produkter i celler af Candida arter
MX2020005724A (es) Variantes de alfa-amilasa y polinucleotidos que codifican las mismas.
ATE450603T1 (de) Polypeptide mit verzweigungsenzym-aktivität und für diese kodierende nukleinsäuren
FR2862312B1 (fr) Outil de transfert et de production de proteines mettant en oeuvre le systeme de secretion de type iii de pseudomonas
DE60036537D1 (de) Zusammensetzungen zur gentherapie von diabetes
WO2022235933A3 (en) Compositions and methods for treating sensorineural hearing loss using stereocilin dual vector systems
SA523451188B1 (ar) شظية ربط مولد الضد مضادة لـليمفوبويتين الغدة الصعترية ذو ثبات محسن
WO2010002160A3 (ko) 돼지의 알파에스 1 카제인 유전자, 그 프로모터 및 그의 용도
MX2017013174A (es) Fusiones de variante iii del receptor de factor de crecimiento epidermico-mesotelina y métodos para usar los mismos.
ATE377649T1 (de) Verfahren und zelle zur expression von rekombinanten proteinprodukten
MX2025002493A (es) Factor de crecimiento derivado de mieloides para su uso en el tratamiento del shock cardiogenico
DOP2025000239A (es) Compuestos y métodos para reducir la expresión de pln
MX2017013088A (es) Metodos novedosos para el control de la aflatoxina y de infecciones fungicas.
WO2022026950A3 (en) Cst6, cells expressing cst6 and methods of use
WO2017062666A3 (en) Enzyme replacement therapy for mucopolysaccharidosis iiid