MX2022007662A - Sintesis de compuestos para promover el crecimiento del cabello. - Google Patents
Sintesis de compuestos para promover el crecimiento del cabello.Info
- Publication number
- MX2022007662A MX2022007662A MX2022007662A MX2022007662A MX2022007662A MX 2022007662 A MX2022007662 A MX 2022007662A MX 2022007662 A MX2022007662 A MX 2022007662A MX 2022007662 A MX2022007662 A MX 2022007662A MX 2022007662 A MX2022007662 A MX 2022007662A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- hair growth
- synthesis
- promote hair
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente descripción hace referencia a un método para sintetizar un compuesto representado por la fórmula I. La presente descripción hace referencia además a los compuestos de la fórmula I (A, B o C) que son capaces de inhibir el portador de piruvato mitocondrial y promover el crecimiento del cabello.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962951667P | 2019-12-20 | 2019-12-20 | |
PCT/US2020/066078 WO2021127482A1 (en) | 2019-12-20 | 2020-12-18 | Synthesis of compounds to promote hair growth |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022007662A true MX2022007662A (es) | 2022-09-21 |
Family
ID=76478595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022007662A MX2022007662A (es) | 2019-12-20 | 2020-12-18 | Sintesis de compuestos para promover el crecimiento del cabello. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20230103693A1 (es) |
EP (1) | EP4077327A4 (es) |
JP (1) | JP2023509360A (es) |
KR (1) | KR20220128361A (es) |
CN (1) | CN115052876A (es) |
AU (1) | AU2020407122A1 (es) |
BR (1) | BR112022012149A2 (es) |
CA (1) | CA3164224A1 (es) |
IL (1) | IL293584A (es) |
MX (1) | MX2022007662A (es) |
WO (1) | WO2021127482A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL271443B2 (en) | 2017-06-30 | 2024-01-01 | Univ California | Preparations and methods for regulating hair growth |
EP4172159A4 (en) * | 2020-06-30 | 2024-01-10 | Univ California | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH |
EP4172158A4 (en) * | 2020-06-30 | 2024-01-10 | Univ California | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200819447A (en) * | 2006-08-31 | 2008-05-01 | Smithkline Beecham Corp | Chemical compounds |
WO2013188554A1 (en) * | 2012-06-12 | 2013-12-19 | The Regents Of The University Of California | Fluorination of aryl compounds |
US20190135747A1 (en) * | 2016-05-12 | 2019-05-09 | Regents Of The University Of Minnesota | Indole and indazole cyanocinnamate compounds and therapeutic uses thereof |
IL271443B2 (en) * | 2017-06-30 | 2024-01-01 | Univ California | Preparations and methods for regulating hair growth |
EP4172158A4 (en) * | 2020-06-30 | 2024-01-10 | Univ California | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH |
-
2020
- 2020-12-18 KR KR1020227025237A patent/KR20220128361A/ko unknown
- 2020-12-18 BR BR112022012149A patent/BR112022012149A2/pt unknown
- 2020-12-18 JP JP2022536957A patent/JP2023509360A/ja active Pending
- 2020-12-18 EP EP20903755.5A patent/EP4077327A4/en active Pending
- 2020-12-18 MX MX2022007662A patent/MX2022007662A/es unknown
- 2020-12-18 AU AU2020407122A patent/AU2020407122A1/en active Pending
- 2020-12-18 IL IL293584A patent/IL293584A/en unknown
- 2020-12-18 US US17/786,986 patent/US20230103693A1/en active Pending
- 2020-12-18 CN CN202080088741.3A patent/CN115052876A/zh active Pending
- 2020-12-18 CA CA3164224A patent/CA3164224A1/en active Pending
- 2020-12-18 WO PCT/US2020/066078 patent/WO2021127482A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
BR112022012149A2 (pt) | 2022-08-30 |
KR20220128361A (ko) | 2022-09-20 |
WO2021127482A1 (en) | 2021-06-24 |
EP4077327A1 (en) | 2022-10-26 |
EP4077327A4 (en) | 2024-02-07 |
AU2020407122A1 (en) | 2022-06-23 |
IL293584A (en) | 2022-08-01 |
US20230103693A1 (en) | 2023-04-06 |
CN115052876A (zh) | 2022-09-13 |
CA3164224A1 (en) | 2021-06-24 |
WO2021127482A8 (en) | 2022-06-30 |
JP2023509360A (ja) | 2023-03-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2022007662A (es) | Sintesis de compuestos para promover el crecimiento del cabello. | |
MX2021000348A (es) | 2-fluoro-3-nitrotolueno cristalino y procedimiento para la preparacion del mismo. | |
MX2022007823A (es) | Composiciones y metodos para modular el crecimiento del cabello. | |
BR112022009390A2 (pt) | Síntese melhorada de composto inibidor de kras g12c | |
MX2021008089A (es) | Composiciones y metodos para modular el crecimiento del cabello. | |
MX2022005726A (es) | Sintesis mejorada del compuesto inhibidor de g12c de kras. | |
MX2017006305A (es) | Bencilpropargileter como inhibidores de la nitrificacion. | |
AU2018274723A1 (en) | Benzimidazolone derived inhibitors of BCL6 | |
MY193210A (en) | Process for producing diazabicyclooctane derivative | |
CY1117923T1 (el) | Αζωτουχος ετεροκυκλικη ενωση και γεωργικο ή κηπουρικο μυκητοκτονο | |
WO2019010363A8 (en) | Synthesis of halichondrins | |
MX2021013531A (es) | Inhibidores de cdk. | |
EP4306526A3 (en) | Compound for photoelectric conversion element | |
AR116790A1 (es) | PROCEDIMIENTO PARA LA PREPARACIÓN DE 3a-HIDROXI-5a-PREGNAN-20-ONA (BREXANOLONA) | |
PH12020500128A1 (en) | Inhibitors of ror gamma | |
MX2018014130A (es) | Procedimiento e intermedios para la 6,7-alfa-epoxidacion de 4,6-dienos esteroideos. | |
MX2017017022A (es) | Metodo para la sintesis de derivados de rapamicina. | |
MX2021001904A (es) | Formas solidas de benzoxaborol sustituido y composiciones de las mismas. | |
WO2020127208A8 (en) | Pharmaceutical process and intermediates | |
MX2021004386A (es) | Compuestos novedosos. | |
EP4249491A3 (en) | Process for preparing bicyclic enolether | |
AU2017239848B2 (en) | Novel compound and synthesis method therefor | |
MX2023000970A (es) | Metodo de preparacion de aminofuranos. | |
MX2009013336A (es) | Sintesis de 3-aminopirazoles sustituidos. | |
MX2019000984A (es) | Proceso para preparacion de indanonas. |