MX2022007202A - Fármacos bioactivables a base de citocinas y metodos de uso de los mismos. - Google Patents

Fármacos bioactivables a base de citocinas y metodos de uso de los mismos.

Info

Publication number
MX2022007202A
MX2022007202A MX2022007202A MX2022007202A MX2022007202A MX 2022007202 A MX2022007202 A MX 2022007202A MX 2022007202 A MX2022007202 A MX 2022007202A MX 2022007202 A MX2022007202 A MX 2022007202A MX 2022007202 A MX2022007202 A MX 2022007202A
Authority
MX
Mexico
Prior art keywords
vitokine
moiety
tissue
domain
bioactivatable
Prior art date
Application number
MX2022007202A
Other languages
English (en)
Spanish (es)
Inventor
Yue-Sheng Li
Jing Xu
Lingyun Rui
Original Assignee
Cugene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cugene Inc filed Critical Cugene Inc
Publication of MX2022007202A publication Critical patent/MX2022007202A/es

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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
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