MX2022007056A - Insertos oculares polimericos disolvibles con un polimero biodegradable. - Google Patents

Insertos oculares polimericos disolvibles con un polimero biodegradable.

Info

Publication number
MX2022007056A
MX2022007056A MX2022007056A MX2022007056A MX2022007056A MX 2022007056 A MX2022007056 A MX 2022007056A MX 2022007056 A MX2022007056 A MX 2022007056A MX 2022007056 A MX2022007056 A MX 2022007056A MX 2022007056 A MX2022007056 A MX 2022007056A
Authority
MX
Mexico
Prior art keywords
biodegradable polymer
polymeric eye
insert
eye inserts
dissolvable polymeric
Prior art date
Application number
MX2022007056A
Other languages
English (en)
Inventor
Rekha Rangarajan
Howard Allen Ketelson
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of MX2022007056A publication Critical patent/MX2022007056A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

Un inserto ocular polimérico, comprendiendo el inserto: un polímero biodegradable y uno o más polímeros mucoadhesivos que son biocompatibles con la superficie ocular y la película lagrimal del ojo; en donde el polímero biodegradable aumenta el tiempo de disolución del inserto ocular polimérico en al menos un 15 por ciento en comparación con el inserto ocular polimérico de control, que es el mismo inserto ocular polimérico excepto que el polímero biodegradable no está presente.
MX2022007056A 2019-12-10 2020-12-08 Insertos oculares polimericos disolvibles con un polimero biodegradable. MX2022007056A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962946060P 2019-12-10 2019-12-10
PCT/IB2020/061644 WO2021116907A1 (en) 2019-12-10 2020-12-08 Dissolvable polymeric eye inserts with a biodegradable polymer

Publications (1)

Publication Number Publication Date
MX2022007056A true MX2022007056A (es) 2022-07-11

Family

ID=73835659

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022007056A MX2022007056A (es) 2019-12-10 2020-12-08 Insertos oculares polimericos disolvibles con un polimero biodegradable.

Country Status (11)

Country Link
US (2) US11395797B2 (es)
EP (1) EP4072521A1 (es)
JP (1) JP7406634B2 (es)
KR (1) KR20220084381A (es)
CN (1) CN114760987A (es)
AU (1) AU2020400389B2 (es)
BR (1) BR112022011067A2 (es)
CA (1) CA3161982A1 (es)
MX (1) MX2022007056A (es)
TW (1) TW202122071A (es)
WO (1) WO2021116907A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114760987A (zh) * 2019-12-10 2022-07-15 爱尔康公司 具有可生物降解聚合物的可溶解性聚合物眼睛插入物
TW202341919A (zh) * 2021-12-23 2023-11-01 瑞士商愛爾康公司 用於角膜表面保護之可溶解醫療裝置及套件
US20230201031A1 (en) * 2021-12-23 2023-06-29 Alcon Inc. Dissolvable medical device for promoting healing of wounds
WO2023119228A1 (en) * 2021-12-23 2023-06-29 Alcon Inc. Dissolvable medical device for drugs delivery
CN116312205B (zh) * 2023-01-04 2024-03-26 郭列维 防近视标识生成方法、印制品、设备、程序产品和介质

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060280774A1 (en) 1995-06-02 2006-12-14 Allergan, Inc. Compositions and methods for treating glaucoma
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
KR20070121754A (ko) * 2005-03-21 2007-12-27 마커사이트, 인코포레이티드 질환 또는 상태의 치료를 위한 약물 송달 시스템
ES2326282T3 (es) * 2005-09-21 2009-10-06 Aston University Sistema de suministro ocular cronoterapeutico que comprende una combinacion de prostaglandina y de un betabloqueante para el tratamiento de un glaucoma primario.
CN101374499A (zh) * 2005-12-19 2009-02-25 科门蒂斯公司 用于眼部施用的局部用美加明制剂及其用途
US20110256185A1 (en) 2010-04-15 2011-10-20 Covalon Technologies Inc. Reinforced tissue shields
US20140105956A1 (en) 2012-10-11 2014-04-17 Rupak BANERJEE Biodegradable polymer based microimplant for ocular drug delivery
WO2015018461A1 (fr) * 2013-08-09 2015-02-12 Genbiotech Compositions therapeutiques comprenant d'acide hyaluronique
EP3188688B1 (en) 2014-09-06 2021-11-03 Integral Biosystems LLC Methods and biocompatible compositions to achieve sustained drug release in the eye
CN107427459A (zh) * 2015-02-24 2017-12-01 伊利诺伊大学董事会 用于治疗干眼病及其他眼科疾病的方法和组合物
CN114760987A (zh) * 2019-12-10 2022-07-15 爱尔康公司 具有可生物降解聚合物的可溶解性聚合物眼睛插入物

Also Published As

Publication number Publication date
US20220323346A1 (en) 2022-10-13
US11395797B2 (en) 2022-07-26
JP2023503524A (ja) 2023-01-30
US11779537B2 (en) 2023-10-10
CN114760987A (zh) 2022-07-15
JP7406634B2 (ja) 2023-12-27
BR112022011067A2 (pt) 2022-08-23
EP4072521A1 (en) 2022-10-19
AU2020400389A1 (en) 2022-07-21
CA3161982A1 (en) 2021-06-17
KR20220084381A (ko) 2022-06-21
AU2020400389B2 (en) 2024-02-15
US20210169781A1 (en) 2021-06-10
WO2021116907A1 (en) 2021-06-17
TW202122071A (zh) 2021-06-16

Similar Documents

Publication Publication Date Title
MX2022007056A (es) Insertos oculares polimericos disolvibles con un polimero biodegradable.
WO2018128698A3 (en) Ethylene polymers and ethylene copolymers for blown films
MX2022004087A (es) Copolimeros de polietileno y sus productos y procedimientos.
BR112021026265A2 (pt) Métodos e sistemas de entrega de dispositivos oculares
AR030730A1 (es) Copolimeros segmentarios y dispersiones acuosas y peliculas que surgen de ellos
WO2008013950A3 (en) Water plasticized high refractive index polymer for ophthalmic applications
MX2020010504A (es) Espectroscopia raman y aprendizaje automatico para el control de calidad.
WO2018167099A3 (en) Accommodative lens device
WO2010056598A3 (en) Biodegradable alpha-2 adrenergic agonist polymeric implants
DE602004022707D1 (es)
SA518400537B1 (ar) تركيب بوليمر وعملية لإنتاج تركيب البوليمر
WO2019199656A8 (en) Multicomponent fibers
MX2017014225A (es) Polietileno para un rendimiento superior de termoformacon de extrusion de lamina.
PE20190665A1 (es) Componente articulado que comprende una composicion de polietileno
MX2021013428A (es) Insertos oculares polimericos disolubles y metodo de uso de los mismos.
WO2016033152A3 (en) Embossed matte and glossy plastic film and methods of making same
MX2019004279A (es) Composiciones con recubrimiento de latex a base de agua con adyuvantes de coalescencia modificadores de la viscosidad.
MY170034A (en) Elastomeric gloves and methods for their production
WO2021101979A8 (en) Knitted component having a foam surface feature
PH12020551138A1 (en) Intraocular lens
MX2021002176A (es) Empaques reciclables con accesorios.
MX2020011040A (es) Composicion para reparar tejido y metodo de fabricacion de la misma.
ZA202102319B (en) Biodegradable profile extruded articles
MX2019005187A (es) Polimeros de acido acrilico neutralizados con iones de sodio y calcio y que tienen una distribucion estrecha del peso molecular.
MY192013A (en) Branched, terminated polyamide compositions