MX2022006130A - Composiciones inyectables de ácido ursodeoxicólico. - Google Patents

Composiciones inyectables de ácido ursodeoxicólico.

Info

Publication number
MX2022006130A
MX2022006130A MX2022006130A MX2022006130A MX2022006130A MX 2022006130 A MX2022006130 A MX 2022006130A MX 2022006130 A MX2022006130 A MX 2022006130A MX 2022006130 A MX2022006130 A MX 2022006130A MX 2022006130 A MX2022006130 A MX 2022006130A
Authority
MX
Mexico
Prior art keywords
ursodeoxycholic acid
injectable compositions
present
ursodeoxycholic
acid
Prior art date
Application number
MX2022006130A
Other languages
English (en)
Inventor
Pradeep Shivakumar
Purushothama Narasiyappa
Kiran Kumar Cherukuri
Original Assignee
Shilpa Medicare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd filed Critical Shilpa Medicare Ltd
Publication of MX2022006130A publication Critical patent/MX2022006130A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Abstract

La presente invención está dirigida a una composición farmacéutica inyectable que comprende (a) ácido ursodesoxicólico y (b) sulfobutiléter-ß-ciclodextrina. Tales composiciones exhiben una solubilidad y estabilidad inesperadas del ácido ursodesoxicólico, lo que permite administrar dosis terapéuticas del ácido ursodesoxicólico sin el uso de grandes cantidades de bases fuertes que están presentes en una cantidad estequiométricamente equivalente al ácido ursodesoxicólico.
MX2022006130A 2019-11-22 2020-11-19 Composiciones inyectables de ácido ursodeoxicólico. MX2022006130A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201941047716 2019-11-22
PCT/IB2020/060883 WO2021099973A1 (en) 2019-11-22 2020-11-19 Injectable compositions of ursodeoxycholic acid

Publications (1)

Publication Number Publication Date
MX2022006130A true MX2022006130A (es) 2022-06-16

Family

ID=75981475

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022006130A MX2022006130A (es) 2019-11-22 2020-11-19 Composiciones inyectables de ácido ursodeoxicólico.

Country Status (9)

Country Link
US (1) US20220378803A1 (es)
EP (1) EP4061333A4 (es)
JP (1) JP7440630B2 (es)
KR (1) KR20220100927A (es)
CN (1) CN114650808A (es)
BR (1) BR112022009784A2 (es)
CA (1) CA3157999A1 (es)
MX (1) MX2022006130A (es)
WO (1) WO2021099973A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220123038A (ko) * 2020-01-28 2022-09-05 실파 메디케어 리미티드 우르소데옥시콜산의 투여 방법
CN115068418B (zh) * 2022-07-20 2022-10-28 奥信阳光(北京)药业科技有限公司 一种熊去氧胆酸口服溶液及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2121599T3 (es) * 1993-08-30 1998-12-01 Medichemie Ag Medicamento que contiene acido ursodeoxicolico en forma de administracion liquida.
IT1282943B1 (it) 1995-12-27 1998-04-02 Sanofi Winthrop S P A Composizione farmaceutica iniettabile__a base di acido ursodesossicoli co o tauroursodesossicolico
EP1147779B1 (en) 2000-04-20 2006-05-31 BIOPROGRESS S.p.A. A method for rendering ursodeoxycholic acid in soluble form pharmaceutical compositions
JP2003063965A (ja) 2001-06-13 2003-03-05 Otsuka Pharmaceut Factory Inc 注射用シロスタゾール水性製剤
FR2981572B1 (fr) * 2011-10-21 2018-01-19 Inopharm Limited Compositions pharmaceutiques d'acide ursodesoxycholique
KR20180036580A (ko) * 2016-09-30 2018-04-09 주식회사 유스바이오팜 수가용화(水加溶化)된 우르소데옥시콜산을 함유하는 염증성 피부질환 또는 중증 소양증 예방 또는 치료용 조성물
WO2018147685A1 (ko) * 2017-02-09 2018-08-16 주식회사 유스바이오팜 우르소데옥시콜산을 함유하는 시각장애 예방 또는 치료용 조성물

Also Published As

Publication number Publication date
JP7440630B2 (ja) 2024-02-28
CA3157999A1 (en) 2021-05-27
BR112022009784A2 (pt) 2022-08-09
KR20220100927A (ko) 2022-07-18
EP4061333A1 (en) 2022-09-28
EP4061333A4 (en) 2023-12-06
JP2023502914A (ja) 2023-01-26
CN114650808A (zh) 2022-06-21
US20220378803A1 (en) 2022-12-01
WO2021099973A1 (en) 2021-05-27

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