MX2022005912A - Compuestos de 1,8-naftiridin-2-ona para el tratamiento de una enfermedad autoinmunitaria. - Google Patents
Compuestos de 1,8-naftiridin-2-ona para el tratamiento de una enfermedad autoinmunitaria.Info
- Publication number
- MX2022005912A MX2022005912A MX2022005912A MX2022005912A MX2022005912A MX 2022005912 A MX2022005912 A MX 2022005912A MX 2022005912 A MX2022005912 A MX 2022005912A MX 2022005912 A MX2022005912 A MX 2022005912A MX 2022005912 A MX2022005912 A MX 2022005912A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- naphthyridin
- treatment
- autoimmune disease
- diastereomer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Abstract
La presente invención se refiere a compuestos de la Fórmula (I), (ver Fórmula) (I), en donde R1 a R3, m y n son como se describen en la presente, y su sal farmacéuticamente aceptable, un enantiómero o diastereómero de los mismos, y composiciones que incluyen los compuestos y métodos de uso de los compuestos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2019120996 | 2019-11-26 | ||
PCT/EP2020/083113 WO2021105072A1 (en) | 2019-11-26 | 2020-11-24 | 1,8-naphthyridin-2-one compounds for the treatment of autoimmune disease |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022005912A true MX2022005912A (es) | 2022-06-24 |
Family
ID=73598065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022005912A MX2022005912A (es) | 2019-11-26 | 2020-11-24 | Compuestos de 1,8-naftiridin-2-ona para el tratamiento de una enfermedad autoinmunitaria. |
Country Status (16)
Country | Link |
---|---|
US (1) | US20230041743A1 (es) |
EP (1) | EP4065586A1 (es) |
JP (1) | JP2023503165A (es) |
KR (1) | KR20220106126A (es) |
CN (1) | CN114728987A (es) |
AR (1) | AR120540A1 (es) |
AU (1) | AU2020393367A1 (es) |
BR (1) | BR112022009856A2 (es) |
CA (1) | CA3156457A1 (es) |
CO (1) | CO2022006942A2 (es) |
CR (1) | CR20220231A (es) |
IL (1) | IL291640A (es) |
MX (1) | MX2022005912A (es) |
PE (1) | PE20221026A1 (es) |
TW (1) | TW202134238A (es) |
WO (1) | WO2021105072A1 (es) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4273773A (en) * | 1979-09-24 | 1981-06-16 | American Home Products Corporation | Antihypertensive tricyclic isoindole derivatives |
US9475813B2 (en) * | 2013-02-08 | 2016-10-25 | Nissan Chemical Industries, Ltd. | Tricyclic pyrrolopyridine compound, and JAK inhibitor |
KR20180094939A (ko) * | 2015-12-17 | 2018-08-24 | 메르크 파텐트 게엠베하 | 폴리시클릭 tlr7/8 안타고니스트 및 면역 질환의 치료에서 이들의 용도 |
WO2018178041A1 (en) * | 2017-03-30 | 2018-10-04 | F. Hoffmann-La Roche Ag | Novel pyrido[2,3-b]indole compounds for the treatment and prophylaxis of bacterial infection |
CN110831600B (zh) * | 2017-04-21 | 2023-10-17 | 医肯纳肿瘤学公司 | 吲哚ahr抑制剂和其用途 |
-
2020
- 2020-11-24 BR BR112022009856A patent/BR112022009856A2/pt not_active Application Discontinuation
- 2020-11-24 MX MX2022005912A patent/MX2022005912A/es unknown
- 2020-11-24 EP EP20812250.7A patent/EP4065586A1/en active Pending
- 2020-11-24 CN CN202080079547.9A patent/CN114728987A/zh active Pending
- 2020-11-24 PE PE2022000770A patent/PE20221026A1/es unknown
- 2020-11-24 JP JP2022530733A patent/JP2023503165A/ja active Pending
- 2020-11-24 CA CA3156457A patent/CA3156457A1/en active Pending
- 2020-11-24 US US17/780,123 patent/US20230041743A1/en active Pending
- 2020-11-24 AR ARP200103253A patent/AR120540A1/es unknown
- 2020-11-24 KR KR1020227017383A patent/KR20220106126A/ko unknown
- 2020-11-24 WO PCT/EP2020/083113 patent/WO2021105072A1/en unknown
- 2020-11-24 AU AU2020393367A patent/AU2020393367A1/en active Pending
- 2020-11-25 TW TW109141393A patent/TW202134238A/zh unknown
-
2022
- 2022-03-23 IL IL291640A patent/IL291640A/en unknown
- 2022-05-25 CO CONC2022/0006942A patent/CO2022006942A2/es unknown
- 2022-11-24 CR CR20220231A patent/CR20220231A/es unknown
Also Published As
Publication number | Publication date |
---|---|
CR20220231A (es) | 2022-06-27 |
PE20221026A1 (es) | 2022-06-16 |
KR20220106126A (ko) | 2022-07-28 |
IL291640A (en) | 2022-05-01 |
CA3156457A1 (en) | 2021-06-03 |
CO2022006942A2 (es) | 2022-06-10 |
EP4065586A1 (en) | 2022-10-05 |
TW202134238A (zh) | 2021-09-16 |
JP2023503165A (ja) | 2023-01-26 |
CN114728987A (zh) | 2022-07-08 |
US20230041743A1 (en) | 2023-02-09 |
BR112022009856A2 (pt) | 2022-08-02 |
WO2021105072A1 (en) | 2021-06-03 |
AR120540A1 (es) | 2022-02-23 |
AU2020393367A1 (en) | 2022-04-14 |
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