MX2021011469A - Combinacion de lisina(s) y antibiotico(s) para tratar o prevenir endocarditis infecciosa debida a bacterias gram-positivas. - Google Patents
Combinacion de lisina(s) y antibiotico(s) para tratar o prevenir endocarditis infecciosa debida a bacterias gram-positivas.Info
- Publication number
- MX2021011469A MX2021011469A MX2021011469A MX2021011469A MX2021011469A MX 2021011469 A MX2021011469 A MX 2021011469A MX 2021011469 A MX2021011469 A MX 2021011469A MX 2021011469 A MX2021011469 A MX 2021011469A MX 2021011469 A MX2021011469 A MX 2021011469A
- Authority
- MX
- Mexico
- Prior art keywords
- infective endocarditis
- plyss2 lysin
- antibiotics
- sub
- mic
- Prior art date
Links
- 206010014665 endocarditis Diseases 0.000 title abstract 2
- 201000007119 infective endocarditis Diseases 0.000 title abstract 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 3
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 3
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- 241000192125 Firmicutes Species 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962822386P | 2019-03-22 | 2019-03-22 | |
| US201962832708P | 2019-04-11 | 2019-04-11 | |
| US201962849093P | 2019-05-16 | 2019-05-16 | |
| US201962898379P | 2019-09-10 | 2019-09-10 | |
| US202062965720P | 2020-01-24 | 2020-01-24 | |
| PCT/US2020/024051 WO2020198073A1 (en) | 2019-03-22 | 2020-03-20 | Method of treating infective endocarditis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021011469A true MX2021011469A (es) | 2021-10-22 |
Family
ID=72611751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021011469A MX2021011469A (es) | 2019-03-22 | 2020-03-20 | Combinacion de lisina(s) y antibiotico(s) para tratar o prevenir endocarditis infecciosa debida a bacterias gram-positivas. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220160842A1 (enExample) |
| EP (1) | EP3941504A4 (enExample) |
| JP (1) | JP2022525914A (enExample) |
| KR (1) | KR20210141667A (enExample) |
| CN (1) | CN114025782A (enExample) |
| AU (1) | AU2020244764A1 (enExample) |
| BR (1) | BR112021018219A2 (enExample) |
| CA (1) | CA3134154A1 (enExample) |
| IL (1) | IL286389A (enExample) |
| MX (1) | MX2021011469A (enExample) |
| WO (1) | WO2020198073A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023023560A1 (en) * | 2021-08-17 | 2023-02-23 | Contrafect Corporation | New uses |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100863692B1 (ko) * | 2006-12-08 | 2008-10-15 | 울산대학교 산학협력단 | 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린유도체 |
| US9034322B2 (en) * | 2011-04-21 | 2015-05-19 | The Rockefeller University | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
| EP2699689A4 (en) * | 2011-04-21 | 2014-12-17 | Univ Utrecht Holding Bv | STREPTOCOCCUS BACTERIOPHAGEN LYSINE FOR THE TREATMENT OF GRAM-POSITIVE BACTERIA IN PETS AND UTILITIES |
| MX389127B (es) * | 2012-05-09 | 2025-03-19 | Contrafect Corp | Lisina de bacteriófago y combinaciones de antibióticos contra bacterias gram positivas. |
| ES2729123T3 (es) * | 2012-05-09 | 2019-10-30 | Contrafect Corp | Rotura de biopelícula con lisina plyss2 |
| EP3349780B1 (en) * | 2015-09-17 | 2022-11-09 | Contrafect Corporation | Lysin polypeptides active against gram-negative bacteria |
| RU2754667C2 (ru) * | 2016-05-12 | 2021-09-06 | Контрафект Корпорейшн | Способ микроразбавления в жидкой среде для оценки и определения минимальной ингибирующей концентрации антибактериальных полипептидов |
| AU2018300062A1 (en) * | 2017-07-10 | 2020-01-30 | Contrafect Corporation | Blood component potentiation of lytic protein anti-bacterial activity and methods and uses thereof |
-
2020
- 2020-03-20 CA CA3134154A patent/CA3134154A1/en active Pending
- 2020-03-20 CN CN202080037982.5A patent/CN114025782A/zh active Pending
- 2020-03-20 BR BR112021018219A patent/BR112021018219A2/pt unknown
- 2020-03-20 EP EP20777214.6A patent/EP3941504A4/en active Pending
- 2020-03-20 US US17/440,916 patent/US20220160842A1/en not_active Abandoned
- 2020-03-20 MX MX2021011469A patent/MX2021011469A/es unknown
- 2020-03-20 AU AU2020244764A patent/AU2020244764A1/en not_active Abandoned
- 2020-03-20 JP JP2021556394A patent/JP2022525914A/ja active Pending
- 2020-03-20 WO PCT/US2020/024051 patent/WO2020198073A1/en not_active Ceased
- 2020-03-20 KR KR1020217034201A patent/KR20210141667A/ko active Pending
-
2021
- 2021-09-14 IL IL286389A patent/IL286389A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20220160842A1 (en) | 2022-05-26 |
| BR112021018219A2 (pt) | 2022-01-18 |
| EP3941504A4 (en) | 2022-12-07 |
| IL286389A (en) | 2021-10-31 |
| CA3134154A1 (en) | 2020-10-01 |
| CN114025782A (zh) | 2022-02-08 |
| AU2020244764A1 (en) | 2021-10-14 |
| WO2020198073A1 (en) | 2020-10-01 |
| EP3941504A1 (en) | 2022-01-26 |
| JP2022525914A (ja) | 2022-05-20 |
| KR20210141667A (ko) | 2021-11-23 |
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