MX2021009070A - Sensores de analitos que emplean multiples enzimas y metodos asociados a los mismos. - Google Patents

Sensores de analitos que emplean multiples enzimas y metodos asociados a los mismos.

Info

Publication number
MX2021009070A
MX2021009070A MX2021009070A MX2021009070A MX2021009070A MX 2021009070 A MX2021009070 A MX 2021009070A MX 2021009070 A MX2021009070 A MX 2021009070A MX 2021009070 A MX2021009070 A MX 2021009070A MX 2021009070 A MX2021009070 A MX 2021009070A
Authority
MX
Mexico
Prior art keywords
active area
multiple enzymes
analyte
product
associated therewith
Prior art date
Application number
MX2021009070A
Other languages
English (en)
Spanish (es)
Inventor
Namvar Kiaie
Benjamin J Feldman
Mark K Sloan
Ashwin Kumar
Michael R Love
Stephen Oja
Tianmei Ouyang
Hyun Cho
Lam N Tran
Original Assignee
Abbott Diabetes Care Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Diabetes Care Inc filed Critical Abbott Diabetes Care Inc
Publication of MX2021009070A publication Critical patent/MX2021009070A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/9029—Oxidoreductases (1.) acting on -CH2- groups (1.17)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/908—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2021009070A 2019-01-28 2020-01-28 Sensores de analitos que emplean multiples enzimas y metodos asociados a los mismos. MX2021009070A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962797566P 2019-01-28 2019-01-28
PCT/US2020/015321 WO2020159927A1 (en) 2019-01-28 2020-01-28 Analyte sensors employing multiple enzymes and methods associated therewith

Publications (1)

Publication Number Publication Date
MX2021009070A true MX2021009070A (es) 2021-09-08

Family

ID=69740596

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2021009070A MX2021009070A (es) 2019-01-28 2020-01-28 Sensores de analitos que emplean multiples enzimas y metodos asociados a los mismos.
MX2025003581A MX2025003581A (es) 2019-01-28 2021-07-28 Sensores de analitos que emplean multiples enzimas y metodos asociados a los mismos

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2025003581A MX2025003581A (es) 2019-01-28 2021-07-28 Sensores de analitos que emplean multiples enzimas y metodos asociados a los mismos

Country Status (13)

Country Link
US (8) US12048539B2 (https=)
EP (5) EP4681636A3 (https=)
JP (3) JP7410158B2 (https=)
CN (2) CN113382680B (https=)
AU (3) AU2020214230B2 (https=)
CA (2) CA3126240A1 (https=)
DK (1) DK3917394T3 (https=)
ES (1) ES2992515T3 (https=)
FI (1) FI3917394T3 (https=)
LT (1) LT3917394T (https=)
MX (2) MX2021009070A (https=)
MY (1) MY198077A (https=)
WO (1) WO2020159927A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3423591T3 (da) 2016-03-04 2024-01-29 Abbott Diabetes Care Inc NAD(P)-afhængige sensitive enzymer, elektroder og sensorer og fremgangsmåder til fremstilling og anvendelse deraf
ES2831076T3 (es) * 2017-11-08 2021-06-07 Hoffmann La Roche Sensor para detectar un analito en un líquido corporal y procedimiento de fabricación del mismo
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
CA3126240A1 (en) 2019-01-28 2020-08-06 Abbott Diabetes Cares Inc. Analyte sensors employing multiple enzymes and methods associated therewith
CN113453620B (zh) 2019-01-28 2024-03-05 美国雅培糖尿病护理公司 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法
CN115038381A (zh) 2020-01-03 2022-09-09 美国雅培糖尿病护理公司 用于检测多种分析物的传感器阵列系统和方法
EP4258991A1 (en) * 2020-12-10 2023-10-18 Abbott Diabetes Care, Inc. Analyte sensors for sensing ketones and methods of using the same
CN116829068A (zh) * 2020-12-10 2023-09-29 美国雅培糖尿病护理公司 用于传感酮的分析物传感器和使用其的方法
AU2021400588B2 (en) * 2020-12-15 2025-04-10 Abbott Diabetes Care Inc. Nad(p) depot for nad(p)-dependent enzyme-based sensors
EP4262556A1 (en) * 2020-12-18 2023-10-25 Abbott Diabetes Care, Inc. Systems and methods for analyte detection
EP4262555B1 (en) * 2020-12-18 2026-01-21 Abbott Diabetes Care, Inc. Systems and methods for analyte detection
US20220192553A1 (en) * 2020-12-23 2022-06-23 Abbott Diabetes Care Inc. Analyte sensors for sensing glutamate and methods of using the same
US12345671B2 (en) 2020-12-30 2025-07-01 Abbott Diabetes Care Inc. Analyte sensors for detecting asparagine and aspartate and methods of use thereof
AU2022205038B2 (en) * 2020-12-31 2025-12-04 Abbott Diabetes Care Inc. Analyte sensors and methods of use thereof
EP4281773A1 (en) 2021-01-22 2023-11-29 Analog Devices International Unlimited Company Sensing assembly
US12226239B2 (en) 2021-09-15 2025-02-18 Lingo Sensing Technology Unlimited Company Systems, devices, and methods for applications for communication with ketone sensors
WO2023091897A1 (en) * 2021-11-19 2023-05-25 Abbott Diabetes Care Inc. Analyte sensors for sensing glutamate and methods of using the same
US12527500B2 (en) * 2021-12-02 2026-01-20 Medtronic Minimed, Inc. Ketone limiting membrane and dual layer membrane approach for ketone sensing
JP2025533414A (ja) 2022-09-15 2025-10-07 アボット ダイアベティス ケア インコーポレイテッド デュアル被検物質センサのためのシステム、装置および方法
CN121843651A (zh) 2023-09-22 2026-04-10 雅培糖尿病护理公司 葡萄糖-酮传感器的决策支持
US20250299818A1 (en) 2024-03-25 2025-09-25 Abbott Diabetes Care Inc. Deployment and use of a continuous analyte monitoring system for improved home monitoring and readmission optimization
WO2026008473A1 (en) * 2024-07-01 2026-01-08 Roche Diabetes Care Gmbh An in vivo analyte sensor and a method of manufacturing an in vivo analyte sensor

Family Cites Families (149)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321123A (en) 1978-04-21 1982-03-23 Matsushita Electric Industrial Co., Ltd. Coenzyme immobilized electrode
GB2067764B (en) 1980-01-09 1984-01-25 Nat Res Dev Transcutaneous gas sensor
US5682884A (en) 1983-05-05 1997-11-04 Medisense, Inc. Strip electrode with screen printing
US4680268A (en) 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US5262035A (en) 1989-08-02 1993-11-16 E. Heller And Company Enzyme electrodes
US5264105A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
JPH04278450A (ja) 1991-03-04 1992-10-05 Adam Heller バイオセンサー及び分析物を分析する方法
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US5322063A (en) 1991-10-04 1994-06-21 Eli Lilly And Company Hydrophilic polyurethane membranes for electrochemical glucose sensors
US5965106A (en) 1992-03-04 1999-10-12 Perimmune Holdings, Inc. In vivo binding pair pretargeting
DE4442253A1 (de) 1994-11-28 1996-05-30 Bayer Corp N D Ges D Staates I Elektrochemischer Enzymbiosensor
US5792621A (en) 1995-06-28 1998-08-11 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Fiber-optic chemiluminescent biosensors for monitoring aqueous alcohols and other water quality parameters
US5696314A (en) 1996-07-12 1997-12-09 Chiron Diagnostics Corporation Multilayer enzyme electrode membranes and methods of making same
US6071391A (en) 1997-09-12 2000-06-06 Nok Corporation Enzyme electrode structure
US6736957B1 (en) 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6579690B1 (en) 1997-12-05 2003-06-17 Therasense, Inc. Blood analyte monitoring through subcutaneous measurement
US6030827A (en) 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6241863B1 (en) 1998-04-27 2001-06-05 Harold G. Monbouquette Amperometric biosensors based on redox enzymes
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US5965105A (en) 1998-06-12 1999-10-12 Council Of Scientific And Industrial Research Process for the synthesis of flyash based Zeolite-A
US6294281B1 (en) 1998-06-17 2001-09-25 Therasense, Inc. Biological fuel cell and method
US5902731A (en) 1998-09-28 1999-05-11 Lifescan, Inc. Diagnostics based on tetrazolium compounds
US6377894B1 (en) 1998-11-30 2002-04-23 Abbott Laboratories Analyte test instrument having improved calibration and communication processes
EP1192269A2 (en) 1999-06-18 2002-04-03 Therasense, Inc. MASS TRANSPORT LIMITED i IN VIVO /i ANALYTE SENSOR
US6514460B1 (en) 1999-07-28 2003-02-04 Abbott Laboratories Luminous glucose monitoring device
US8268143B2 (en) 1999-11-15 2012-09-18 Abbott Diabetes Care Inc. Oxygen-effect free analyte sensor
DE60035123T2 (de) 1999-11-15 2008-01-31 Therasense, Inc., Alameda Übergangsmetallkomplexe, die über ein bewegliches zwischenglied an ein polymer gebunden sind
US8444834B2 (en) 1999-11-15 2013-05-21 Abbott Diabetes Care Inc. Redox polymers for use in analyte monitoring
US6541216B1 (en) 1999-12-22 2003-04-01 Roche Diagnostics Corporation Amperometric biosensor test strip
WO2001088524A1 (en) 2000-05-12 2001-11-22 Therasense, Inc. Electrodes with multilayer membranes and methods of using and making the electrodes
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6676816B2 (en) 2001-05-11 2004-01-13 Therasense, Inc. Transition metal complexes with (pyridyl)imidazole ligands and sensors using said complexes
US6932894B2 (en) 2001-05-15 2005-08-23 Therasense, Inc. Biosensor membranes composed of polymers containing heterocyclic nitrogens
US6915147B2 (en) 2001-09-07 2005-07-05 Medtronic Minimed, Inc. Sensing apparatus and process
US6984307B2 (en) 2001-10-05 2006-01-10 Stephen Eliot Zweig Dual glucose-hydroxybutyrate analytical sensors
GB0130684D0 (en) 2001-12-21 2002-02-06 Oxford Biosensors Ltd Micro-band electrode
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US6946299B2 (en) 2002-04-25 2005-09-20 Home Diagnostics, Inc. Systems and methods for blood glucose sensing
US20040061232A1 (en) 2002-09-27 2004-04-01 Medtronic Minimed, Inc. Multilayer substrate
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
JP4839569B2 (ja) 2003-06-05 2011-12-21 ソニー株式会社 酵素固定化電極およびその製造方法ならびに電極反応利用装置およびその製造方法
WO2007120442A2 (en) 2003-07-25 2007-10-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7460898B2 (en) 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
WO2005040404A1 (en) 2003-10-29 2005-05-06 Agency For Science, Technology And Research Biosensor
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US8414489B2 (en) * 2003-11-13 2013-04-09 Medtronic Minimed, Inc. Fabrication of multi-sensor arrays
US7577470B2 (en) * 2003-11-13 2009-08-18 Medtronic Minimed, Inc. Long term analyte sensor array
ATE480761T1 (de) 2003-12-05 2010-09-15 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US8423114B2 (en) * 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8948836B2 (en) 2003-12-26 2015-02-03 Medtronic Minimed, Inc. Implantable apparatus for sensing multiple parameters
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US20070270672A1 (en) 2004-08-31 2007-11-22 Hayter Paul G Wearable Sensor Device and System
US8211038B2 (en) 2004-09-17 2012-07-03 Abbott Diabetes Care Inc. Multiple-biosensor article
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US8060174B2 (en) 2005-04-15 2011-11-15 Dexcom, Inc. Analyte sensing biointerface
US20070095661A1 (en) 2005-10-31 2007-05-03 Yi Wang Method of making, and, analyte sensor
JP2007163268A (ja) 2005-12-13 2007-06-28 Canon Inc 酵素電極
JP4802842B2 (ja) 2006-04-24 2011-10-26 株式会社デンソー 健康管理支援装置及び健康管理システム
US9700252B2 (en) 2006-06-19 2017-07-11 Roche Diabetes Care, Inc. Amperometric sensor and method for its manufacturing
US7822557B2 (en) 2006-10-31 2010-10-26 Abbott Diabetes Care Inc. Analyte sensors and methods
US8808515B2 (en) 2007-01-31 2014-08-19 Abbott Diabetes Care Inc. Heterocyclic nitrogen containing polymers coated analyte monitoring device and methods of use
CA2690742C (en) 2007-06-21 2018-05-15 Abbott Diabetes Care Inc. Health management devices and methods
PL2205964T3 (pl) 2007-09-24 2015-12-31 Bayer Healthcare Llc Czujniki testowe, sposoby oraz systemy o wielu rejonach i potencjałach
US20100268043A1 (en) 2007-11-07 2010-10-21 Ofer Yodfat Device and Method for Preventing Diabetic Complications
WO2009100082A1 (en) 2008-02-04 2009-08-13 Bayer Healthcare Llc Semiconductor based analyte sensors and methods
WO2009105337A2 (en) 2008-02-20 2009-08-27 Dexcom, Inc. Continuous medicament sensor system for in vivo use
JP2009245930A (ja) 2008-03-12 2009-10-22 Sony Corp 燃料電池およびその製造方法ならびに酵素固定化電極およびその製造方法ならびに電子機器
US8396528B2 (en) * 2008-03-25 2013-03-12 Dexcom, Inc. Analyte sensor
JP2009272179A (ja) 2008-05-08 2009-11-19 Sony Corp 新規な酵素電極及び該酵素電極を用いた燃料電池
US8620398B2 (en) 2008-06-02 2013-12-31 Abbott Diabetes Care Inc. Reference electrodes having an extended lifetime for use in long term amperometric sensors
US8636884B2 (en) 2008-09-15 2014-01-28 Abbott Diabetes Care Inc. Cationic polymer based wired enzyme formulations for use in analyte sensors
WO2010041511A1 (ja) 2008-10-06 2010-04-15 ソニー株式会社 燃料電池および酵素電極
US8608922B2 (en) * 2008-11-07 2013-12-17 The University Of Connecticut Biosensor for continuous monitoring of metabolites and proteins and methods of manufacture thereof
US20100198034A1 (en) 2009-02-03 2010-08-05 Abbott Diabetes Care Inc. Compact On-Body Physiological Monitoring Devices and Methods Thereof
FI3912551T3 (fi) 2009-02-26 2023-10-31 Abbott Diabetes Care Inc Parannettuja analyyttiantureita ja menetelmiä niiden valmistamiseksi ja käyttämiseksi
US20100213057A1 (en) * 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
US20100331643A1 (en) 2009-06-30 2010-12-30 Abbott Diabetes Care Inc. Extruded Analyte Sensors and Methods of Using Same
US9351677B2 (en) 2009-07-02 2016-05-31 Dexcom, Inc. Analyte sensor with increased reference capacity
EP2473963A4 (en) 2009-08-31 2014-01-08 Abbott Diabetes Care Inc MEDICAL DEVICES AND METHOD
EP2473847B1 (en) 2009-09-04 2016-08-24 Lifescan Scotland Limited Glucose measurement method and system
WO2011031675A1 (en) 2009-09-08 2011-03-17 Abbott Diabetes Care Inc. Methods and articles of manufacture for hosting a safety critical application on an uncontrolled data processing device
US20120181189A1 (en) 2009-09-24 2012-07-19 Fresenius Medical Care Holdings, Inc. Amperometric Creatinine Biosensor With Immobilized Enzyme-Polymer Composition And Systems Using Same, And Methods
US8545693B2 (en) 2009-09-29 2013-10-01 Lifescan Scotland Limited Analyte measurment method and system
US20120283537A1 (en) * 2009-10-30 2012-11-08 Petisce James R Analyte sensor layers and methods related thereto
US9042954B2 (en) 2009-11-24 2015-05-26 Abbott Diabetes Care Inc. Analyte sensors comprising hydrogel membranes
US8354013B2 (en) 2009-11-24 2013-01-15 Abbott Diabetes Care Inc. Analyte sensors comprising high-boiling point solvents
US20110124993A1 (en) 2009-11-24 2011-05-26 Abbott Diabetes Care Inc. Analyte Sensors Comprising Self-Polymerizing Hydrogels
US8497359B2 (en) 2010-02-26 2013-07-30 Ppg Industries Ohio, Inc. Cationic electrodepositable coating composition comprising lignin
AU2011239548A1 (en) 2010-04-16 2012-01-19 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US20110256024A1 (en) 2010-04-16 2011-10-20 Abbott Diabetes Care Inc. Modular Analyte Monitoring Device
JP5423580B2 (ja) 2010-05-17 2014-02-19 トヨタ自動車株式会社 酵素電極およびそれを備えるバイオ燃料電池
US9402574B2 (en) * 2010-06-25 2016-08-02 The University Of Connecticut Sensors for analyte detection and methods of manufacture thereof
DK2598021T3 (da) 2010-07-28 2015-09-28 Abbott Diabetes Care Inc Analytsensorer med temperaturuafhængige membraner
EP2608715B1 (en) 2010-08-24 2016-06-22 Microchips, Inc. Implantable biosensor device and methods of use thereof
WO2012068393A1 (en) 2010-11-18 2012-05-24 Abbott Diabetes Care Inc. Adaptor for on-body analyte monitoring system
US9468402B2 (en) 2010-12-01 2016-10-18 Pinnacle Technology, Inc. Tissue implantable microbiosensor
US20120138484A1 (en) 2010-12-03 2012-06-07 Abbott Diabetes Care Inc. Analyte Sensors Comprising Thickeners, Enzyme Stabilizers and Osmium Boronates
FI3954781T3 (fi) 2010-12-09 2024-10-08 Abbott Diabetes Care Inc Analyyttiantureita, joissa on havaintopinta, jossa on pieniä havaintopisteitä
US8608921B2 (en) 2011-01-20 2013-12-17 Medtronic Minimed, Inc. Layered enzyme compositions for use with analyte sensors
CA3277222A1 (en) 2011-02-28 2025-10-30 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US9380965B2 (en) 2011-05-20 2016-07-05 Abbott Diabetes Care Inc. Analyte sensors having a membrane with low temperature sensitivity
FI2720610T3 (fi) 2011-06-17 2025-09-30 Abbott Diabetes Care Inc Pinottu analyyttianturi, jonka ensimmäinen elektrodi on kapeampi kuin anturin toinen elektrodi
EP3677182B1 (en) 2011-11-07 2022-05-04 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US20140054171A1 (en) 2012-02-21 2014-02-27 Abbott Diabetes Care Inc. Analyte Sensor Utilizing Oxygen as Oxidant
US9535027B2 (en) 2012-07-25 2017-01-03 Abbott Diabetes Care Inc. Analyte sensors and methods of using same
US9743871B2 (en) * 2012-09-24 2017-08-29 Dexcom, Inc. Multiple electrode system for a continuous analyte sensor, and related methods
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
US9344777B2 (en) * 2012-12-20 2016-05-17 Abbott Diabetes Care Inc. Wireless communication authentication for medical monitoring device
JP2014160024A (ja) 2013-02-20 2014-09-04 Jnc Corp 酵素修飾電極、該酵素修飾電極の製造方法、およびこれを用いた電気化学反応装置、並びにそれを用いた化学物質の製造方法
US9487811B2 (en) 2013-03-15 2016-11-08 Abbott Point Of Care Inc. Biosensor structures for improved point of care testing and methods of manufacture thereof
US9562874B2 (en) 2013-03-15 2017-02-07 Abbott Point Of Care Inc. Biosensor with improved interference characteristics
EP3087771B1 (en) 2013-12-27 2020-06-17 Abbott Diabetes Care, Inc. Systems, devices, and methods for authentication in an analyte monitoring environment
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
US20170121754A1 (en) 2014-06-20 2017-05-04 Abbott Diabetes Care Inc. Test Strip, Meter, and Method for Assaying Enzyme Activity
WO2016025064A1 (en) 2014-08-15 2016-02-18 Abbott Diabetes Care Inc. Temperature insensitive in vivo analyte devices, methods and systems
BR112017001444B1 (pt) 2014-08-25 2022-08-16 F. Hoffmann-La Roche Ag Método para detectar pelo menos um analito em uma amostra de teste, elemento sensor, dispositivo de teste, sistema de teste, uso do elemento sensor e portador de dados
WO2016033204A2 (en) * 2014-08-26 2016-03-03 Echo Therapeutics, Inc. Differential biosensor system
GB201507506D0 (en) 2015-04-30 2015-06-17 Inside Biometrics Ltd Electrochemical test device
GB201507508D0 (en) 2015-04-30 2015-06-17 Inside Biometrics Ltd Electrochemical Test Device
JP6584821B2 (ja) 2015-04-30 2019-10-02 株式会社東芝 測定用セル、検出装置および分析装置
US10410538B2 (en) * 2015-05-07 2019-09-10 Dexcom, Inc. System and method for educating users, including responding to patterns
US10780222B2 (en) 2015-06-03 2020-09-22 Pacific Diabetes Technologies Inc Measurement of glucose in an insulin delivery catheter by minimizing the adverse effects of insulin preservatives
WO2016196993A2 (en) 2015-06-04 2016-12-08 Omni Biomedical, Inc. Multi-mediator reagent formulations for use in electrochemical detection
AU2016280696B2 (en) 2015-06-15 2021-11-18 Abbott Diabetes Care Inc. Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
US10238346B2 (en) 2015-09-25 2019-03-26 Sanmina Corporation System and method for a biosensor integrated in a vehicle
EP3394252B1 (en) 2015-12-21 2020-04-29 F. Hoffmann-La Roche AG Mutant 3-hydroxybutyrate dehydrogenase from alcaligenes faecalis as well as methods and uses involving the same
ES2782199T3 (es) 2016-02-09 2020-09-11 Hoffmann La Roche 3-Hidroxibutirato deshidrogenasa mutante de Rhodobacter sphaeroides, así como procedimientos y usos que implican la misma
DK3423591T3 (da) 2016-03-04 2024-01-29 Abbott Diabetes Care Inc NAD(P)-afhængige sensitive enzymer, elektroder og sensorer og fremgangsmåder til fremstilling og anvendelse deraf
US10324058B2 (en) 2016-04-28 2019-06-18 Medtronic Minimed, Inc. In-situ chemistry stack for continuous glucose sensors
KR102372113B1 (ko) 2016-10-05 2022-03-07 에프. 호프만-라 로슈 아게 다중 분석물 진단 테스트 엘리먼트들을 위한 검출 시약들 및 전극 배열들, 그리고 그것을 사용하는 방법들
WO2018067878A1 (en) 2016-10-05 2018-04-12 Abbott Laboratories Devices and methods for sample analysis
EP3531120A4 (en) 2016-10-24 2020-06-10 PHC Holdings Corporation ELECTRON MEDIATOR OXIDIZING AGENT
EP4538692A3 (en) 2017-06-30 2025-06-18 Abbott Diabetes Care Method and apparatus for analyte detection using an electrochemical biosensor
DE202018006591U1 (de) 2017-08-18 2021-07-21 Abbott Diabetes Care, Inc. Systeme und Vorrichtungen betreffend die individualisierte Kalibrierung und/oder Herstellung von medizinischen Vorrichtungen
EP3703564A1 (en) 2017-10-30 2020-09-09 Abbott Diabetes Care Inc. Transcutaneous sensor with dual electrodes and methods of detecting and compensating for withdrawal of a transcutaneous sensor from a patient
US12076145B2 (en) 2018-04-19 2024-09-03 Abbott Diabetes Care Inc. Lactate sensors and associated methods
US11744492B2 (en) 2018-08-29 2023-09-05 Medtronic, Inc. Electrochemical sensor including multiple work electrodes and common reference electrode
JP2022509742A (ja) 2018-12-07 2022-01-24 バイオリンク，インク． 生理学的流体中の循環ケトン体のレベル上昇の測定
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
CN113453620B (zh) 2019-01-28 2024-03-05 美国雅培糖尿病护理公司 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法
EP4552566A1 (en) 2019-01-28 2025-05-14 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods for detecting creatinine
CA3126240A1 (en) 2019-01-28 2020-08-06 Abbott Diabetes Cares Inc. Analyte sensors employing multiple enzymes and methods associated therewith
EP3948249A4 (en) 2019-03-24 2023-11-22 Baldwa, Mehul BIOSENSOR FOR DETECTING ANALYTES IN A FLUID
CN115038381A (zh) 2020-01-03 2022-09-09 美国雅培糖尿病护理公司 用于检测多种分析物的传感器阵列系统和方法

Also Published As

Publication number Publication date
ES2992515T3 (es) 2024-12-13
CN119279579A (zh) 2025-01-10
US12575769B2 (en) 2026-03-17
US20250261884A1 (en) 2025-08-21
EP4725415A2 (en) 2026-04-15
AU2026201074A1 (en) 2026-03-05
CA3126240A1 (en) 2020-08-06
EP3917394A1 (en) 2021-12-08
US12150761B2 (en) 2024-11-26
AU2020214230A1 (en) 2021-08-19
FI3917394T3 (fi) 2024-11-12
EP3917394B1 (en) 2024-08-14
US20200237276A1 (en) 2020-07-30
US20260020797A1 (en) 2026-01-22
EP4681636A3 (en) 2026-04-15
EP4487774A3 (en) 2025-03-26
JP7410158B2 (ja) 2024-01-09
AU2020214230B2 (en) 2023-03-02
US20260020799A1 (en) 2026-01-22
US20210137431A1 (en) 2021-05-13
CA3281699A1 (en) 2026-03-02
US20240350047A1 (en) 2024-10-24
MY198077A (en) 2023-07-31
DK3917394T3 (da) 2024-11-11
US20220386910A1 (en) 2022-12-08
EP4487774A2 (en) 2025-01-08
MX2025003581A (es) 2025-05-02
WO2020159927A1 (en) 2020-08-06
EP4663121A1 (en) 2025-12-17
JP7669463B2 (ja) 2025-04-28
JP2025105636A (ja) 2025-07-10
US12048539B2 (en) 2024-07-30
AU2023203330A1 (en) 2023-06-22
EP4681636A2 (en) 2026-01-21
CN113382680A (zh) 2021-09-10
JP2022518569A (ja) 2022-03-15
US12004858B2 (en) 2024-06-11
LT3917394T (lt) 2024-12-27
JP2024023776A (ja) 2024-02-21
US20260020798A1 (en) 2026-01-22
AU2023203330B2 (en) 2025-11-20
CN113382680B (zh) 2024-08-20

Similar Documents

Publication Publication Date Title
MX2021009070A (es) Sensores de analitos que emplean multiples enzimas y metodos asociados a los mismos.
MX2021008964A (es) Sensores analiticos y metodos de deteccion con deteccion dual de glucosa y cetonas.
González-Fernández et al. Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection
MX2008014250A (es) Sistema de deteccion de salida anormal para biosensor.
US20100252452A1 (en) Apparatus and method for electrochemical detection
WO2020037269A3 (en) Composite matrix for analyte biosensors
NO20073209L (no) Biosensorer omfattende halvledende elektroder eller ruthemnnholdige mediatorer, samt fremgangsmate for a anvende slike
AR027345A1 (es) Metodos electroquimicos y dispositivos para usar en la determinacion de concentraciones de analito con rectificacion de hematocrito
EP3343213A3 (en) Sensor
EP4647504A3 (en) Stabilized lactate responsive enzymes, electrodes and sensors, and methods for making and using the same
EP1734362A3 (en) Disposable oxygen sensor and method for correcting oxygen effect on oxidase-based analytical devices
Baskar et al. Simultaneous detection of NADH and H2O2 using flow injection analysis based on a bifunctional poly (thionine)-modified electrode
Bretón-Romero et al. Hydrogen peroxide signaling mediator in the activation of p38 MAPK in vascular endothelial cells
BR112017014097A2 (pt) tira de teste e sistema e método para medir a concentração de glicose em amostra de sangue
WO2002068473A8 (en) Biosensor for detecting chemical agents
WO2014006394A3 (en) An electrode and use thereof
Ikeda et al. Evaluation of bacterial activity based on the electrochemical properties of tetrazolium salts
CN104076014A (zh) 一种荧光传感器，其制备方法，用途以及检测Heparin分子的方法
MX2022001800A (es) Microelectrodo de ion selectivo de magnesio en estado solido mejorado y metodos de produccion y uso del mismo.
CN103940870A (zh) 一种基于酶催化的细胞内嘌呤电化学检测方法
RU2012153849A (ru) Способ оценки токсичности продукции из полимерных и текстильных материалов
MX391120B (es) Nanoperlas que contiene biosensores, métodos de producción y uso de las mismas
Turunc et al. Electrochemical determination of glutathione in plasma at carbon nanotubes based screen printed electrodes
WO2004065963A3 (en) Improved beta-arrestin based screening assays
UA118713C2 (uk) Портативна амперометрична біосенсорна система для визначення концентрації молочної та піровиноградної кислот у розчині