MX2021006661A - Proceso para la preparacion de 5-bromo-1,3-dicloro-2-fluoro-bencen o. - Google Patents

Proceso para la preparacion de 5-bromo-1,3-dicloro-2-fluoro-bencen o.

Info

Publication number
MX2021006661A
MX2021006661A MX2021006661A MX2021006661A MX2021006661A MX 2021006661 A MX2021006661 A MX 2021006661A MX 2021006661 A MX2021006661 A MX 2021006661A MX 2021006661 A MX2021006661 A MX 2021006661A MX 2021006661 A MX2021006661 A MX 2021006661A
Authority
MX
Mexico
Prior art keywords
dichloro
fluoro
bromo
benzene
preparation
Prior art date
Application number
MX2021006661A
Other languages
English (en)
Inventor
Michael Rack
Birgit Gockel
Martin John Mclaughlin
Sebastian Soergel
Karsten Koerber
Devendra Vyas
Pascal Bindschaedler
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of MX2021006661A publication Critical patent/MX2021006661A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/35—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/02—Monocyclic aromatic halogenated hydrocarbons
    • C07C25/08—Dichloro-benzenes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/18—Carbon
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44—Palladium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/52—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/20—Diazonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/045—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/26—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms
    • C07C39/27—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms all halogen atoms being bound to ring carbon atoms
    • C07C39/30—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms all halogen atoms being bound to ring carbon atoms the halogen being two chlorine atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals
    • C07C2523/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals of the platinum group metals
    • C07C2523/44—Palladium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invención se refiere a un proceso para la preparación de 5-bromo-1,3-dicloro-2-fluoro-benceno mediante la diazotización y reducción de 6-bromo-2,4-dicloro-3-fluoro-anilina, que se obtiene mediante la bromación de 2,4-dicloro-3-fluoro-anilina, que se obtiene mediante la reducción de 1,3-dicloro-2-fluoro-4-nitro-benc eno, y un proceso para preparar compuestos activos de la Fórmula V (ver Fórmula) en donde las variables se definen en la memoria descriptiva al transformar adicionalmente 5-bromo-1,3-dicloro-2-fl uoro-benceno obtenido de 2,4-dicloro-3-fluoro-anilina mediante el proceso de acuerdo con la invención.
MX2021006661A 2018-12-04 2019-11-25 Proceso para la preparacion de 5-bromo-1,3-dicloro-2-fluoro-bencen o. MX2021006661A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18209956 2018-12-04
PCT/EP2019/082352 WO2020114813A1 (en) 2018-12-04 2019-11-25 Process for preparation of 5-bromo-1,3-dichloro-2-fluoro-benzene

Publications (1)

Publication Number Publication Date
MX2021006661A true MX2021006661A (es) 2021-07-07

Family

ID=64604475

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021006661A MX2021006661A (es) 2018-12-04 2019-11-25 Proceso para la preparacion de 5-bromo-1,3-dicloro-2-fluoro-bencen o.

Country Status (10)

Country Link
US (1) US11440861B2 (es)
EP (1) EP3891113B1 (es)
KR (1) KR20210100149A (es)
CN (1) CN113166004A (es)
AU (1) AU2019391253A1 (es)
BR (1) BR112021009123A2 (es)
CA (1) CA3120221A1 (es)
IL (1) IL283448A (es)
MX (1) MX2021006661A (es)
WO (1) WO2020114813A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112028736A (zh) * 2020-09-10 2020-12-04 内蒙古永太化学有限公司 一种3,5-二氯-4-氟溴苯化合物的制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0507786A (pt) * 2004-02-20 2007-07-17 Astrazeneca Ab composto e sais farmaceuticamente aceitáveis do mesmo, formulação farmacêutica, uso de um composto, método de tratar uma doença, e, processo para a preparação de compostos
ZA200607637B (en) 2004-03-05 2008-05-28 Nissan Chemical Ind Ltd Isoxazoline-substituted benzamide compound and noxious organism control agent
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
TWI583664B (zh) 2008-04-09 2017-05-21 杜邦股份有限公司 羰基化合物及其製備方法
WO2010020522A1 (en) 2008-08-22 2010-02-25 Syngenta Participations Ag Insecticidal compounds
EP2393493A4 (en) 2009-01-30 2013-07-17 Glaxosmithkline Llc LINKS
WO2010125130A1 (en) 2009-04-30 2010-11-04 Basf Se Process for preparing substituted isoxazoline compounds and their precursors
ES2502340T3 (es) 2009-06-22 2014-10-03 Syngenta Participations Ag Compuestos insecticidas
TWI487486B (zh) * 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
WO2012007426A1 (en) 2010-07-13 2012-01-19 Basf Se Azoline substituted isoxazoline benzamide compounds for combating animal pests
BR112013023068B8 (pt) 2011-03-10 2022-11-22 Zoetis Llc Derivados de isoxazolina espirocíclica, seu uso e seu processo de preparação, e composições veterinárias
AR086587A1 (es) 2011-05-31 2014-01-08 Syngenta Participations Ag Compuestos insecticidas
WO2013026929A1 (en) 2011-08-25 2013-02-28 Syngenta Participations Ag Dihydropyrrole derivatives as insecticidal compounds
CN103224452B (zh) 2012-01-30 2015-07-15 江苏英力科技发展有限公司 一种2-溴-4,6-二氯苯胺的制备方法
CN103664511B (zh) 2013-12-13 2015-07-08 浙江林江化工股份有限公司 一种3,5-二氯-4-氟溴苯的制备方法
DK3207009T3 (da) 2014-10-14 2020-07-27 Syngenta Participations Ag Fremgangsmåde til fremstilling af halogensubstituerede benzener
EP3237380B1 (en) * 2014-12-22 2019-04-03 Basf Se Azoline compounds substituted by a carbocyclic condensed ring system
CN107108596B (zh) 2014-12-22 2021-01-12 巴斯夫欧洲公司 被稠合环体系取代的唑啉类化合物
CN105801429B (zh) * 2014-12-31 2019-09-24 安徽新北卡化学有限公司 一种3,5-二氯-2,4-二氟苯胺的制备方法
US9420793B2 (en) * 2015-01-16 2016-08-23 Avista Pharma Solutions Antiparasitic compounds
CN105439810B (zh) * 2015-02-15 2017-04-12 浙江永太科技股份有限公司 一种3,4,5‑三氟溴苯化合物的制备方法
RU2019136972A (ru) * 2017-04-26 2021-05-26 Басф Се Замещенные сукцинимидные производные в качестве пестицидов

Also Published As

Publication number Publication date
KR20210100149A (ko) 2021-08-13
CA3120221A1 (en) 2020-06-11
WO2020114813A1 (en) 2020-06-11
CN113166004A (zh) 2021-07-23
EP3891113A1 (en) 2021-10-13
US11440861B2 (en) 2022-09-13
US20220017439A1 (en) 2022-01-20
IL283448A (en) 2021-07-29
AU2019391253A1 (en) 2021-06-03
EP3891113B1 (en) 2022-08-17
BR112021009123A2 (pt) 2021-08-10

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