MX2021002533A - Dispositivos y metodos para pruebas de susceptibilidad a antibioticos. - Google Patents

Dispositivos y metodos para pruebas de susceptibilidad a antibioticos.

Info

Publication number
MX2021002533A
MX2021002533A MX2021002533A MX2021002533A MX2021002533A MX 2021002533 A MX2021002533 A MX 2021002533A MX 2021002533 A MX2021002533 A MX 2021002533A MX 2021002533 A MX2021002533 A MX 2021002533A MX 2021002533 A MX2021002533 A MX 2021002533A
Authority
MX
Mexico
Prior art keywords
snp
diagnostic devices
treatment
molecular diagnostic
methods
Prior art date
Application number
MX2021002533A
Other languages
English (en)
Inventor
David Swenson
Gary Schoolnik
Phoebe Cao
Bryan D Knysh
Teresa M Abraham
Original Assignee
Visby Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visby Medical Inc filed Critical Visby Medical Inc
Publication of MX2021002533A publication Critical patent/MX2021002533A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0663—Stretching or orienting elongated molecules or particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La descripción se refiere generalmente a dispositivos de diagnóstico molecular configurados para amplificar un locus de polimorfismo de un solo nucleótido (SNP) y discriminar entre dos o más variantes alélicas del SNP, lo que indica la presencia o ausencia de un alelo objetivo. En algunas modalidades, los dispositivos de diagnóstico molecular son capaces de detectar, en el punto de atención, SNP asociados con resistencia o susceptibilidad al tratamiento con antibióticos de infecciones bacterianas. En otros aspectos, la descripción proporciona métodos de tratamiento para enfermedades o trastornos (por ejemplo, infecciones bacterianas) donde el tratamiento se guía por la presencia o ausencia de un alelo en un locus de SNP como se determina por tales dispositivos de diagnóstico molecular.
MX2021002533A 2018-09-03 2019-09-03 Dispositivos y metodos para pruebas de susceptibilidad a antibioticos. MX2021002533A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862726379P 2018-09-03 2018-09-03
US201962820359P 2019-03-19 2019-03-19
PCT/US2019/049385 WO2020051156A1 (en) 2018-09-03 2019-09-03 Devices and methods for antibiotic susceptibility testing

Publications (1)

Publication Number Publication Date
MX2021002533A true MX2021002533A (es) 2021-05-27

Family

ID=69721930

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021002533A MX2021002533A (es) 2018-09-03 2019-09-03 Dispositivos y metodos para pruebas de susceptibilidad a antibioticos.

Country Status (11)

Country Link
US (1) US20210299669A1 (es)
EP (1) EP3846940A4 (es)
JP (1) JP2021534804A (es)
KR (1) KR20210081335A (es)
CN (1) CN112930228A (es)
AU (1) AU2019337088A1 (es)
CA (1) CA3111751A1 (es)
IL (1) IL281193A (es)
MX (1) MX2021002533A (es)
SG (1) SG11202102098WA (es)
WO (1) WO2020051156A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3240906B1 (en) 2014-12-31 2021-08-25 Visby Medical, Inc. Devices for molecular diagnostic testing
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
US11352675B2 (en) 2020-01-03 2022-06-07 Visby Medical, Inc. Devices and methods for antibiotic susceptability testing
AU2022203005A1 (en) * 2021-05-21 2022-12-08 Silvec Biologics Inc. Plant vectors, compositions and uses relating thereto
CN117230222A (zh) * 2023-10-18 2023-12-15 鲲鹏基因（北京）科技有限责任公司 检测结核分枝杆菌喹诺酮耐药的组合物、试剂盒及方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994066A (en) * 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
DK2574681T3 (en) * 2007-03-28 2016-07-04 Signal Diagnostics System and method for high-resolution analysis of nucleic acids to detect sequence variations
US20130295570A1 (en) * 2010-10-07 2013-11-07 Brandeis University Compositions and methods for nucleic acid based diagnostic assays
IN2014DN04226A (es) * 2011-11-14 2015-05-22 Gen Hospital Corp
KR101184566B1 (ko) * 2012-05-11 2012-09-20 케이맥(주) 실시간 중합효소 연쇄반응과 ｄｎａ 칩이 통합된 검사 시스템 및 이를 이용한 통합 분석방법
MX356055B (es) * 2013-09-06 2018-05-11 Theranos Ip Co Llc Sistemas y métodos para detectar enfermedades infecciosas.
CN103820439B (zh) * 2014-02-25 2017-07-07 广东省结核病控制中心 结核分枝杆菌链霉素耐药相关的新突变位点及其应用
AU2015358251A1 (en) * 2014-12-05 2017-06-29 University Of Saskatchewan Methods and reagents for detecting neisseria gonorrhoeae and its antimicrobial resistance determinants
WO2016106391A1 (en) * 2014-12-22 2016-06-30 The Broad Institute, Inc. Rapid quantitative detection of single nucleotide polymorphisms or somatic variants and methods to identify malignant neoplasms
WO2016138471A1 (en) * 2015-02-26 2016-09-01 IDGenomics, Inc. Process and kit for predicting antibiotic resistance and susceptibility of bacteria
US9708647B2 (en) * 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US20180355410A1 (en) * 2015-06-19 2018-12-13 Cambridge Enterprise Limited Diagnosis and treatment of infectious disease
ITUB20160413A1 (it) * 2016-02-05 2017-08-05 Thd Spa Metodo per determinare Helicobacter pylori
WO2017185067A1 (en) * 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
US11031099B2 (en) * 2016-11-09 2021-06-08 Roche Molecular Systems, Inc. Detection of sequence variants

Also Published As

Publication number Publication date
CA3111751A1 (en) 2020-03-12
EP3846940A1 (en) 2021-07-14
AU2019337088A1 (en) 2021-05-06
US20210299669A1 (en) 2021-09-30
CN112930228A (zh) 2021-06-08
JP2021534804A (ja) 2021-12-16
KR20210081335A (ko) 2021-07-01
EP3846940A4 (en) 2022-07-27
SG11202102098WA (en) 2021-04-29
WO2020051156A1 (en) 2020-03-12
IL281193A (en) 2021-04-29

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