MX2021001613A - Anticuerpos anti-factor xi. - Google Patents

Anticuerpos anti-factor xi.

Info

Publication number
MX2021001613A
MX2021001613A MX2021001613A MX2021001613A MX2021001613A MX 2021001613 A MX2021001613 A MX 2021001613A MX 2021001613 A MX2021001613 A MX 2021001613A MX 2021001613 A MX2021001613 A MX 2021001613A MX 2021001613 A MX2021001613 A MX 2021001613A
Authority
MX
Mexico
Prior art keywords
antibodies
factor
fxia
fxi
thrombosis
Prior art date
Application number
MX2021001613A
Other languages
English (en)
Spanish (es)
Inventor
Wenyi Wang
Quan Yu
Xiaowu Liu
John Liuzhong Xu
Zhiqiang Du
Original Assignee
Shanghai Benemae Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Benemae Pharmaceutical Corp filed Critical Shanghai Benemae Pharmaceutical Corp
Publication of MX2021001613A publication Critical patent/MX2021001613A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2021001613A 2018-08-09 2018-08-09 Anticuerpos anti-factor xi. MX2021001613A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2018/099638 WO2020029179A1 (en) 2018-08-09 2018-08-09 Anti-factor xi antibodies

Publications (1)

Publication Number Publication Date
MX2021001613A true MX2021001613A (es) 2021-04-28

Family

ID=69413757

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021001613A MX2021001613A (es) 2018-08-09 2018-08-09 Anticuerpos anti-factor xi.

Country Status (9)

Country Link
EP (1) EP3833692A1 (ko)
JP (1) JP2021534098A (ko)
KR (1) KR20210042352A (ko)
CN (4) CN116554334A (ko)
AU (1) AU2018436195A1 (ko)
BR (1) BR112021002472A2 (ko)
CA (1) CA3108708A1 (ko)
MX (1) MX2021001613A (ko)
WO (1) WO2020029179A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody
CN116554334A (zh) * 2018-08-09 2023-08-08 上海仁会生物制药股份有限公司 抗凝血因子xi抗体
US20220089777A1 (en) * 2019-01-21 2022-03-24 Aronora, Inc. Novel humanized antibodies against factor xi having anti-thrombotic and anti-inflammatory effect and uses thereof
US20230343982A1 (en) 2021-03-31 2023-10-26 Lg Energy Solution, Ltd. Mono-Cell Manufacturing Apparatus with Gloss Meter and Manufacturing Method Using the Same
CN116410258A (zh) * 2023-04-13 2023-07-11 上海太阳生物技术有限公司 因子xi缺乏血浆保护剂及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014202009A1 (en) * 2007-11-21 2014-05-01 Oregon Health & Science University Anti-factor xi monoclonal antibodies and methods of use thereof
PT3002298T (pt) * 2007-11-21 2019-11-20 Univ Oregon Health & Science Anticorpos monoclonais anti-fator xi e métodos de utilização dos mesmos
TR201820051T4 (tr) * 2008-06-19 2019-01-21 Prothix Bv Anti-faktör XI Antikorlarının Trombüs Oluşumunun Engellenmesi Veya Tedavisi İçin Kullanılması
DK2373691T3 (en) * 2008-12-18 2019-04-15 Oregon Health&Science Univ ANTI-FXI ANTIBODIES AND PROCEDURES FOR USE
JP6348900B2 (ja) * 2012-05-10 2018-06-27 バイエル ファーマ アクチエンゲゼルシャフト 凝固因子xiおよび/またはその活性化形態である因子xiaに結合しうる抗体ならびにその用途
JOP20200312A1 (ar) * 2015-06-26 2017-06-16 Novartis Ag الأجسام المضادة للعامل xi وطرق الاستخدام
AU2017209083A1 (en) * 2016-01-22 2018-07-12 Adimab, Llc Anti-coagulation factor XI antibodies
CA3018124A1 (en) * 2016-03-23 2017-09-28 Prothix Bv Monoclonal antibodies against the active site of factor xi and uses thereof
CN108409863B (zh) * 2017-02-10 2023-09-26 上海仁会生物制药股份有限公司 抗凝血因子xi抗体
CN116554334A (zh) * 2018-08-09 2023-08-08 上海仁会生物制药股份有限公司 抗凝血因子xi抗体

Also Published As

Publication number Publication date
CN114478781B (zh) 2024-04-02
KR20210042352A (ko) 2021-04-19
BR112021002472A2 (pt) 2021-07-27
CN114478781A (zh) 2022-05-13
WO2020029179A1 (en) 2020-02-13
CN114478782A (zh) 2022-05-13
JP2021534098A (ja) 2021-12-09
CA3108708A1 (en) 2020-02-13
CN114478782B (zh) 2024-04-02
CN113227150B (zh) 2023-07-28
EP3833692A1 (en) 2021-06-16
CN116554334A (zh) 2023-08-08
AU2018436195A1 (en) 2021-02-18
CN113227150A (zh) 2021-08-06

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