MX2020013885A - Anticuerpos anti-cd40 para su uso en el tratamiento de enfermedades autoinmunes. - Google Patents

Anticuerpos anti-cd40 para su uso en el tratamiento de enfermedades autoinmunes.

Info

Publication number
MX2020013885A
MX2020013885A MX2020013885A MX2020013885A MX2020013885A MX 2020013885 A MX2020013885 A MX 2020013885A MX 2020013885 A MX2020013885 A MX 2020013885A MX 2020013885 A MX2020013885 A MX 2020013885A MX 2020013885 A MX2020013885 A MX 2020013885A
Authority
MX
Mexico
Prior art keywords
antibodies
autoimmune disease
treating autoimmune
therapeutic
compositions
Prior art date
Application number
MX2020013885A
Other languages
English (en)
Inventor
David P Joseph
Juergen Theodor Steffgen
James Michael Hilbert
Patanjali Ravva
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2020013885A publication Critical patent/MX2020013885A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Abstract

La presente invención se relaciona con nuevos anticuerpos anti-CD40 antagonistas humanizados y métodos terapéuticos y diagnósticos y composiciones para uso de los mismos.
MX2020013885A 2018-06-29 2019-06-28 Anticuerpos anti-cd40 para su uso en el tratamiento de enfermedades autoinmunes. MX2020013885A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862691766P 2018-06-29 2018-06-29
PCT/US2019/039715 WO2020006347A1 (en) 2018-06-29 2019-06-28 Anti-cd40 antibodies for use in treating autoimmune disease

Publications (1)

Publication Number Publication Date
MX2020013885A true MX2020013885A (es) 2021-03-09

Family

ID=67297421

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020013885A MX2020013885A (es) 2018-06-29 2019-06-28 Anticuerpos anti-cd40 para su uso en el tratamiento de enfermedades autoinmunes.

Country Status (13)

Country Link
US (1) US20210261678A1 (es)
EP (1) EP3813950A1 (es)
JP (1) JP2021529754A (es)
KR (1) KR20210027436A (es)
CN (1) CN112334195A (es)
AU (1) AU2019291890A1 (es)
BR (1) BR112020024078A2 (es)
CA (1) CA3101469A1 (es)
CL (1) CL2020003348A1 (es)
EA (1) EA202190094A1 (es)
MX (1) MX2020013885A (es)
PH (1) PH12020552235A1 (es)
WO (1) WO2020006347A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220089759A1 (en) * 2020-09-21 2022-03-24 Boehringer Ingelheim International Gmbh Use of anti-cd40 antibodies for treatment of inflammatory conditions
WO2022165171A1 (en) 2021-01-28 2022-08-04 Regeneron Pharmaceuticals, Inc. Compositions and methods for treating cytokine release syndrome
CN117295764A (zh) * 2021-06-28 2023-12-26 江苏恒瑞医药股份有限公司 抗cd40抗体、其抗原结合片段及医药用途
WO2023198194A1 (en) * 2022-04-15 2023-10-19 Biocytogen Pharmaceuticals (Beijing) Co., Ltd. Anti-cd40 antibodies and uses thereof

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Also Published As

Publication number Publication date
BR112020024078A2 (pt) 2021-02-17
CA3101469A1 (en) 2020-01-02
KR20210027436A (ko) 2021-03-10
EA202190094A1 (ru) 2021-04-21
JP2021529754A (ja) 2021-11-04
EP3813950A1 (en) 2021-05-05
WO2020006347A1 (en) 2020-01-02
CL2020003348A1 (es) 2021-07-19
PH12020552235A1 (en) 2021-06-28
US20210261678A1 (en) 2021-08-26
CN112334195A (zh) 2021-02-05
AU2019291890A1 (en) 2020-12-17

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