MX2020009412A - Sales y polimorfos de un compuesto imidazopiridinil-aminopiridina sustituido. - Google Patents

Sales y polimorfos de un compuesto imidazopiridinil-aminopiridina sustituido.

Info

Publication number
MX2020009412A
MX2020009412A MX2020009412A MX2020009412A MX2020009412A MX 2020009412 A MX2020009412 A MX 2020009412A MX 2020009412 A MX2020009412 A MX 2020009412A MX 2020009412 A MX2020009412 A MX 2020009412A MX 2020009412 A MX2020009412 A MX 2020009412A
Authority
MX
Mexico
Prior art keywords
compound
salts
polymorphs
free base
forms
Prior art date
Application number
MX2020009412A
Other languages
English (en)
Inventor
Jianmin Mao
Craig Bates
David Reed
Original Assignee
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arqule Inc filed Critical Arqule Inc
Publication of MX2020009412A publication Critical patent/MX2020009412A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente solicitud se refiere a sales del compuesto A, 3-(3-(4-(1-aminociclobutil) fenil)-5- fenil-3H-imidazo[4,5-b] piridin-2-il)piridin-2-amina, formas sólidas de la base libre del compuesto A o de las sales del compuesto A, formas amorfas de la base libre del compuesto A o de sales del compuesto A, formas cristalinas de la base libre del compuesto A o de sales del compuesto A, polimorfos de la base libre del compuesto A o de sales del compuesto A y mesomorfos de la base libre de compuesto A o de sales del compuesto A; la presente solicitud también se refiere a composiciones farmacéuticas que comprenden estas sales, formas de estado sólido, formas amorfas, formas cristalinas, polimorfos o mesomorfos de la base libre del compuesto A o de sales del compuesto A; la presente solicitud proporciona métodos para preparar estas sales, formas sólidas, formas amorfas, formas cristalinas, polimorfos o mesomorfos de la base libre del compuesto A o de las sales del compuesto A.
MX2020009412A 2014-04-22 2016-10-21 Sales y polimorfos de un compuesto imidazopiridinil-aminopiridina sustituido. MX2020009412A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461982692P 2014-04-22 2014-04-22

Publications (1)

Publication Number Publication Date
MX2020009412A true MX2020009412A (es) 2020-10-05

Family

ID=54321420

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016013911A MX2016013911A (es) 2014-04-22 2015-04-22 Sales y polimorfos de un compuesto imidazopiridinil-aminopiridina sustituido.
MX2020009412A MX2020009412A (es) 2014-04-22 2016-10-21 Sales y polimorfos de un compuesto imidazopiridinil-aminopiridina sustituido.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2016013911A MX2016013911A (es) 2014-04-22 2015-04-22 Sales y polimorfos de un compuesto imidazopiridinil-aminopiridina sustituido.

Country Status (20)

Country Link
US (1) US9422283B2 (es)
EP (2) EP3134407B1 (es)
JP (2) JP6961348B2 (es)
KR (1) KR20160143842A (es)
CN (2) CN111499627A (es)
AU (2) AU2015249809B2 (es)
BR (1) BR112016024521A2 (es)
CA (1) CA2945778A1 (es)
DK (1) DK3134407T3 (es)
ES (1) ES2745156T3 (es)
HU (1) HUE046150T2 (es)
IL (1) IL248342A (es)
MX (2) MX2016013911A (es)
PL (1) PL3134407T3 (es)
PT (1) PT3134407T (es)
RU (1) RU2732125C2 (es)
SG (1) SG11201608722QA (es)
TW (1) TWI652266B (es)
WO (1) WO2015164479A1 (es)
ZA (1) ZA201607107B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220024617A (ko) * 2019-07-17 2022-03-03 서밋 (옥스포드) 리미티드 리디닐라졸 및 이의 결정 형태의 제조방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
EP1277754B8 (en) * 2000-04-27 2005-09-28 Astellas Pharma Inc. Imidazopyridine derivatives
US6403588B1 (en) * 2000-04-27 2002-06-11 Yamanouchi Pharmaceutical Co., Ltd. Imidazopyridine derivatives
GB0206860D0 (en) * 2002-03-22 2002-05-01 Glaxo Group Ltd Compounds
EP2251341A1 (en) * 2005-07-14 2010-11-17 Astellas Pharma Inc. Heterocyclic Janus kinase 3 inhibitors
EP2004625B1 (en) * 2006-03-22 2009-12-30 Vertex Pharmaceuticals Incorporated C-met protein kinase inhibitors for the treatment of proliferative disorders
US8136543B2 (en) * 2009-01-27 2012-03-20 Fisher Controls International, Llc Axial flow control valves having an internal actuator
IT1395963B1 (it) * 2009-06-04 2012-11-02 Rottapharm Spa Forme cristalline di 6-(1h-imidazol-1-il)-2-fenil chinazolina e dei suoi sali
DK2519522T3 (en) * 2009-12-30 2014-12-08 Arqule Inc SUBSTITUTED IDAZOPYRIDINYL AMINOPYRIDINE COMPOUNDS
CN103748093B (zh) * 2011-06-24 2016-06-01 艾科尔公司 被取代的咪唑并吡啶基-氨基吡啶化合物
WO2012177852A1 (en) 2011-06-24 2012-12-27 Arqule, Inc Substituted imidazopyridinyl compounds

Also Published As

Publication number Publication date
RU2732125C2 (ru) 2020-09-11
IL248342A (en) 2017-07-31
PL3134407T3 (pl) 2019-11-29
WO2015164479A1 (en) 2015-10-29
JP2017513890A (ja) 2017-06-01
JP2020073523A (ja) 2020-05-14
PT3134407T (pt) 2019-09-27
BR112016024521A2 (pt) 2017-08-15
AU2019206118B2 (en) 2020-07-23
AU2019206118A1 (en) 2019-08-08
CA2945778A1 (en) 2015-10-29
AU2015249809A1 (en) 2016-11-03
EP3653627A1 (en) 2020-05-20
TWI652266B (zh) 2019-03-01
EP3134407B1 (en) 2019-07-10
CN106795153A (zh) 2017-05-31
HUE046150T2 (hu) 2020-02-28
KR20160143842A (ko) 2016-12-14
US20150299195A1 (en) 2015-10-22
EP3134407A4 (en) 2017-09-13
TW201625606A (zh) 2016-07-16
AU2015249809B2 (en) 2019-05-02
CN106795153B (zh) 2020-03-20
US9422283B2 (en) 2016-08-23
DK3134407T3 (da) 2019-09-23
MX2016013911A (es) 2017-03-07
ES2745156T3 (es) 2020-02-27
ZA201607107B (en) 2018-05-30
RU2016145264A3 (es) 2019-01-24
CN111499627A (zh) 2020-08-07
JP6961348B2 (ja) 2021-11-05
SG11201608722QA (en) 2016-11-29
EP3134407A1 (en) 2017-03-01
RU2016145264A (ru) 2018-05-23

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