SG11201608722QA - Salts and polymorphs of a substituted imidazopyridinyl-aminopyridine compound - Google Patents

Salts and polymorphs of a substituted imidazopyridinyl-aminopyridine compound

Info

Publication number
SG11201608722QA
SG11201608722QA SG11201608722QA SG11201608722QA SG11201608722QA SG 11201608722Q A SG11201608722Q A SG 11201608722QA SG 11201608722Q A SG11201608722Q A SG 11201608722QA SG 11201608722Q A SG11201608722Q A SG 11201608722QA SG 11201608722Q A SG11201608722Q A SG 11201608722QA
Authority
SG
Singapore
Prior art keywords
polymorphs
salts
aminopyridine compound
substituted imidazopyridinyl
imidazopyridinyl
Prior art date
Application number
SG11201608722QA
Inventor
Craig Bates
Jianmin Mao
David Reed
Original Assignee
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arqule Inc filed Critical Arqule Inc
Publication of SG11201608722QA publication Critical patent/SG11201608722QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201608722QA 2014-04-22 2015-04-22 Salts and polymorphs of a substituted imidazopyridinyl-aminopyridine compound SG11201608722QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461982692P 2014-04-22 2014-04-22
PCT/US2015/027045 WO2015164479A1 (en) 2014-04-22 2015-04-22 Salts and polymorphs of a substituted imidazopyridinyl-aminopyridine compound

Publications (1)

Publication Number Publication Date
SG11201608722QA true SG11201608722QA (en) 2016-11-29

Family

ID=54321420

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201608722QA SG11201608722QA (en) 2014-04-22 2015-04-22 Salts and polymorphs of a substituted imidazopyridinyl-aminopyridine compound

Country Status (20)

Country Link
US (1) US9422283B2 (en)
EP (2) EP3134407B1 (en)
JP (2) JP6961348B2 (en)
KR (1) KR20160143842A (en)
CN (2) CN111499627A (en)
AU (2) AU2015249809B2 (en)
BR (1) BR112016024521A2 (en)
CA (1) CA2945778A1 (en)
DK (1) DK3134407T3 (en)
ES (1) ES2745156T3 (en)
HU (1) HUE046150T2 (en)
IL (1) IL248342A (en)
MX (2) MX2016013911A (en)
PL (1) PL3134407T3 (en)
PT (1) PT3134407T (en)
RU (1) RU2732125C2 (en)
SG (1) SG11201608722QA (en)
TW (1) TWI652266B (en)
WO (1) WO2015164479A1 (en)
ZA (1) ZA201607107B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220024617A (en) * 2019-07-17 2022-03-03 서밋 (옥스포드) 리미티드 Process for the preparation of ridinylazole and its crystalline form

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
ATE300540T1 (en) * 2000-04-27 2005-08-15 Yamanouchi Pharma Co Ltd IMIDAZOPYRIDINE DERIVATIVES
US6403588B1 (en) * 2000-04-27 2002-06-11 Yamanouchi Pharmaceutical Co., Ltd. Imidazopyridine derivatives
GB0206860D0 (en) * 2002-03-22 2002-05-01 Glaxo Group Ltd Compounds
EP2251341A1 (en) * 2005-07-14 2010-11-17 Astellas Pharma Inc. Heterocyclic Janus kinase 3 inhibitors
WO2007111904A2 (en) * 2006-03-22 2007-10-04 Vertex Pharmaceuticals Incorporated C-met protein kinase inhibitors for the treatment of proliferative disorders
US8136543B2 (en) * 2009-01-27 2012-03-20 Fisher Controls International, Llc Axial flow control valves having an internal actuator
IT1395963B1 (en) * 2009-06-04 2012-11-02 Rottapharm Spa CRYSTALLINE FORMS OF 6- (1H-IMIDAZOL-1-IL) -2-FENYL CHINAZOLIN AND OF ITS SALTS
SG181947A1 (en) 2009-12-30 2012-07-30 Arqule Inc Substituted imidazopyridinyl-aminopyridine compounds
US8815854B2 (en) 2011-06-24 2014-08-26 Arqule, Inc. Substituted imidazopyridinyl compounds
CA2837727C (en) 2011-06-24 2019-12-03 Arqule, Inc. Substituted imidazopyridinyl-aminopyridine compounds

Also Published As

Publication number Publication date
JP6961348B2 (en) 2021-11-05
KR20160143842A (en) 2016-12-14
CA2945778A1 (en) 2015-10-29
EP3134407A1 (en) 2017-03-01
TW201625606A (en) 2016-07-16
EP3134407A4 (en) 2017-09-13
JP2017513890A (en) 2017-06-01
RU2732125C2 (en) 2020-09-11
CN111499627A (en) 2020-08-07
TWI652266B (en) 2019-03-01
AU2019206118A1 (en) 2019-08-08
JP2020073523A (en) 2020-05-14
PL3134407T3 (en) 2019-11-29
US20150299195A1 (en) 2015-10-22
RU2016145264A (en) 2018-05-23
AU2019206118B2 (en) 2020-07-23
WO2015164479A1 (en) 2015-10-29
ES2745156T3 (en) 2020-02-27
IL248342A (en) 2017-07-31
EP3134407B1 (en) 2019-07-10
AU2015249809B2 (en) 2019-05-02
US9422283B2 (en) 2016-08-23
BR112016024521A2 (en) 2017-08-15
AU2015249809A1 (en) 2016-11-03
ZA201607107B (en) 2018-05-30
CN106795153B (en) 2020-03-20
HUE046150T2 (en) 2020-02-28
DK3134407T3 (en) 2019-09-23
MX2016013911A (en) 2017-03-07
CN106795153A (en) 2017-05-31
EP3653627A1 (en) 2020-05-20
PT3134407T (en) 2019-09-27
RU2016145264A3 (en) 2019-01-24
MX2020009412A (en) 2020-10-05

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