MX2020004809A - Produccion de guayano y rotundona. - Google Patents
Produccion de guayano y rotundona.Info
- Publication number
- MX2020004809A MX2020004809A MX2020004809A MX2020004809A MX2020004809A MX 2020004809 A MX2020004809 A MX 2020004809A MX 2020004809 A MX2020004809 A MX 2020004809A MX 2020004809 A MX2020004809 A MX 2020004809A MX 2020004809 A MX2020004809 A MX 2020004809A
- Authority
- MX
- Mexico
- Prior art keywords
- rotundone
- guaiene
- production
- guayane
- produced
- Prior art date
Links
- NUWMTBMCSQWPDG-SDDRHHMPSA-N Rotundone Chemical compound C1([C@H](CC[C@H](C2)C(C)=C)C)=C2[C@@H](C)CC1=O NUWMTBMCSQWPDG-SDDRHHMPSA-N 0.000 title abstract 2
- NUWMTBMCSQWPDG-UHFFFAOYSA-N Rotundone Natural products C1C(C(C)=C)CCC(C)C2=C1C(C)CC2=O NUWMTBMCSQWPDG-UHFFFAOYSA-N 0.000 title abstract 2
- 101710093888 Pentalenene synthase Proteins 0.000 abstract 2
- 101710115850 Sesquiterpene synthase Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
- C12P7/38—Cyclopentanone- or cyclopentadione-containing products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/203—Alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/03—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/613—Unsaturated compounds containing a keto groups being part of a ring polycyclic
- C07C49/617—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
- C07C49/623—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings
- C07C49/637—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings the condensed ring system containing ten carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/0042—Essential oils; Perfumes compounds containing condensed hydrocarbon rings
- C11B9/0046—Essential oils; Perfumes compounds containing condensed hydrocarbon rings containing only two condensed rings
- C11B9/0049—Essential oils; Perfumes compounds containing condensed hydrocarbon rings containing only two condensed rings the condensed rings sharing two common C atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/002—Preparation of hydrocarbons or halogenated hydrocarbons cyclic
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
- C07C2602/30—Azulenes; Hydrogenated azulenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fats And Perfumes (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención se relaciona con un proceso para producir rotundona a partir de a-guayano, en particular por oxidación de la posición C(3), en donde el a-guayano se produce a partir de un precursor por una sesquiterpeno sintasa. La sesquiterpeno sintasa se produce en un microorganismo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17205361.3A EP3495489A1 (en) | 2017-12-05 | 2017-12-05 | Production of guaiene and rotundone |
PCT/EP2018/082007 WO2019110299A1 (en) | 2017-12-05 | 2018-11-21 | Production of guaiene and rotundone |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020004809A true MX2020004809A (es) | 2020-08-13 |
Family
ID=60627438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020004809A MX2020004809A (es) | 2017-12-05 | 2018-11-21 | Produccion de guayano y rotundona. |
Country Status (8)
Country | Link |
---|---|
US (2) | US11485985B2 (es) |
EP (2) | EP3495489A1 (es) |
JP (1) | JP7489315B2 (es) |
CN (1) | CN111511923A (es) |
BR (1) | BR112020010246A2 (es) |
MX (1) | MX2020004809A (es) |
SG (1) | SG11202004381WA (es) |
WO (1) | WO2019110299A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3752624A1 (en) * | 2018-02-14 | 2020-12-23 | Ginkgo Bioworks Inc. | Chimeric terpene synthases |
US11618908B2 (en) * | 2018-09-06 | 2023-04-04 | Manus Bio Inc. | Microbial production of rotundone |
WO2020179503A1 (ja) * | 2019-03-01 | 2020-09-10 | 長谷川香料株式会社 | セスキテルペン酸素付加体の製造方法、化合物および組成物 |
CN111205302B (zh) * | 2020-01-10 | 2021-03-30 | 贵州景诚制药有限公司 | 一种大果木姜子果实提取物、提取方法及制备方法和应用 |
GB202115380D0 (en) | 2021-10-26 | 2021-12-08 | Givaudan Sa | Organic compounds |
NL2031120B1 (en) * | 2022-02-16 | 2023-08-22 | Sestina Bio Llc | Engineered alpha-guaiene synthases |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2074880A1 (en) * | 1991-08-12 | 1993-02-13 | James E. Lyons | Allylic oxidation of olefins |
BRPI0416912B1 (pt) | 2003-11-26 | 2020-01-28 | Firmenich & Cie | método para a produção de patchoulol, método para preparar uma patchoulol sintase funcional variante, construção de ácido nucleico, vetor, método de obtenção de uma célula hospedeira recombinante, célula de microrganismo hospedeira, método de fabricação de uma patchoulol sintase |
US20130172625A1 (en) * | 2010-02-26 | 2013-07-04 | Vertellus Special Ties Inc | Methods for using allylic oxidation catalysts to perform oxidation reactions |
EP2402301A1 (en) * | 2010-06-29 | 2012-01-04 | Givaudan SA | 1-hydroxy-octahydroazulenes as fragrances |
JP6522551B2 (ja) * | 2016-06-10 | 2019-05-29 | 長谷川香料株式会社 | (−)−ロタンドンの製造方法 |
-
2017
- 2017-12-05 EP EP17205361.3A patent/EP3495489A1/en not_active Withdrawn
-
2018
- 2018-11-21 US US16/765,649 patent/US11485985B2/en active Active
- 2018-11-21 EP EP18804000.0A patent/EP3720966A1/en active Pending
- 2018-11-21 SG SG11202004381WA patent/SG11202004381WA/en unknown
- 2018-11-21 CN CN201880078721.0A patent/CN111511923A/zh active Pending
- 2018-11-21 WO PCT/EP2018/082007 patent/WO2019110299A1/en unknown
- 2018-11-21 MX MX2020004809A patent/MX2020004809A/es unknown
- 2018-11-21 BR BR112020010246-6A patent/BR112020010246A2/pt unknown
- 2018-11-21 JP JP2020530557A patent/JP7489315B2/ja active Active
-
2022
- 2022-09-28 US US17/936,072 patent/US20230040990A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20200299737A1 (en) | 2020-09-24 |
US11485985B2 (en) | 2022-11-01 |
CN111511923A (zh) | 2020-08-07 |
JP7489315B2 (ja) | 2024-05-23 |
JP2021505140A (ja) | 2021-02-18 |
WO2019110299A1 (en) | 2019-06-13 |
BR112020010246A2 (pt) | 2020-10-13 |
US20230040990A1 (en) | 2023-02-09 |
SG11202004381WA (en) | 2020-06-29 |
EP3720966A1 (en) | 2020-10-14 |
EP3495489A1 (en) | 2019-06-12 |
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