MX2020002958A - Compuestos de porfirina sustituidos con fluoro, composiciones farmaceuticas que comprenden los mismos y metodos de preparacion y uso de los mismos. - Google Patents

Compuestos de porfirina sustituidos con fluoro, composiciones farmaceuticas que comprenden los mismos y metodos de preparacion y uso de los mismos.

Info

Publication number
MX2020002958A
MX2020002958A MX2020002958A MX2020002958A MX2020002958A MX 2020002958 A MX2020002958 A MX 2020002958A MX 2020002958 A MX2020002958 A MX 2020002958A MX 2020002958 A MX2020002958 A MX 2020002958A MX 2020002958 A MX2020002958 A MX 2020002958A
Authority
MX
Mexico
Prior art keywords
same
methods
porphyrin compounds
preparing
pharmaceutical compositions
Prior art date
Application number
MX2020002958A
Other languages
English (en)
Spanish (es)
Inventor
Ines Batinic-Haberle
Ivan Spasojevic
Artak Tovmasyan
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Publication of MX2020002958A publication Critical patent/MX2020002958A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/32Manganese; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005Compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1094Shielding, protecting against radiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2020002958A 2017-09-29 2018-09-26 Compuestos de porfirina sustituidos con fluoro, composiciones farmaceuticas que comprenden los mismos y metodos de preparacion y uso de los mismos. MX2020002958A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762565436P 2017-09-29 2017-09-29
PCT/US2018/052826 WO2019067523A1 (en) 2017-09-29 2018-09-26 FLUOROSUBSTITUTED PORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF PREPARATION AND USE THEREOF

Publications (1)

Publication Number Publication Date
MX2020002958A true MX2020002958A (es) 2020-08-20

Family

ID=65903171

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020002958A MX2020002958A (es) 2017-09-29 2018-09-26 Compuestos de porfirina sustituidos con fluoro, composiciones farmaceuticas que comprenden los mismos y metodos de preparacion y uso de los mismos.

Country Status (8)

Country Link
US (1) US11344574B2 (enExample)
EP (1) EP3687551A4 (enExample)
JP (1) JP7336805B2 (enExample)
KR (1) KR102699638B1 (enExample)
CN (1) CN111417400B (enExample)
CA (1) CA3076008A1 (enExample)
MX (1) MX2020002958A (enExample)
WO (1) WO2019067523A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX394244B (es) 2017-04-04 2025-03-24 Biomimetix Jv Llc Metodos, composiciones, y kits para tratar y/o prevenir un efecto secundario asociado con radiacion y/o exposicion a quimioterapia
EP3687551A4 (en) 2017-09-29 2021-06-23 Duke University FLUORUSUBSTITUTED PORPHYRINE COMPOUNDS, THESE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE AND USE
CN115192705B (zh) * 2021-04-13 2023-10-13 中国科学院化学研究所 一种两性离子共价有机聚合物/二氧化钛纳米复合材料及其制备方法和应用
CN116333037A (zh) * 2021-12-17 2023-06-27 化学与精细化工广东省实验室 含巯基肽与氟代卟啉类偶联用作生物探针

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2520735B2 (ja) * 1988-07-14 1996-07-31 東洋薄荷工業株式会社 ポルフィリン誘導体
EP1045851B1 (en) 1997-11-03 2003-04-23 Duke University Substituted porphyrins
JPH11217385A (ja) * 1998-01-30 1999-08-10 Nihon Schering Kk 含フッ素ポルフィリン錯体およびそれを含有する造影剤
US6448239B1 (en) 1999-06-03 2002-09-10 Trustees Of Princeton University Peroxynitrite decomposition catalysts and methods of use thereof
US20030050297A1 (en) 2001-01-19 2003-03-13 Crapo James D. Cancer therapy
EP1718201B1 (en) 2004-02-09 2016-09-14 Duke University Substituted porphyrins
BRPI0509359A (pt) * 2004-03-29 2007-09-04 Inotek Pharmaceuticals Corp compostos de porfirina substituìda por piridila e métodos de empregos destes
CN101235036A (zh) 2007-02-02 2008-08-06 济南赛文医药技术有限公司 一类卟啉衍生物及其作为小分子抗氧化剂的应用
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
WO2010080881A1 (en) * 2009-01-07 2010-07-15 Duke University Substituted porphyrins
WO2015034778A1 (en) 2013-09-03 2015-03-12 Biomimetix J.V., Llc Methods of treating erectile dysfunction
US10080759B2 (en) 2014-01-22 2018-09-25 Duke University Methods of treating pruritus
US10064871B2 (en) 2014-01-22 2018-09-04 Biomimetix Jv, Llc Methods of treating skin disorders
EP3558902A4 (en) * 2016-12-20 2020-06-24 Duke University METHOD FOR PRODUCING PHARMACEUTICAL COMPOUNDS WITH SUBSTITUTED PORPHYRINE AND COMPOSITIONS
WO2018237249A1 (en) 2017-06-22 2018-12-27 Biomimetix Jv, Llc Methods, compositions, and kits for treating inflammatory skin conditions
EP3687551A4 (en) 2017-09-29 2021-06-23 Duke University FLUORUSUBSTITUTED PORPHYRINE COMPOUNDS, THESE PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE AND USE

Also Published As

Publication number Publication date
KR102699638B1 (ko) 2024-08-28
JP7336805B2 (ja) 2023-09-01
CN111417400B (zh) 2022-12-02
CN111417400A (zh) 2020-07-14
US20210361702A1 (en) 2021-11-25
EP3687551A1 (en) 2020-08-05
EP3687551A4 (en) 2021-06-23
US11344574B2 (en) 2022-05-31
CA3076008A1 (en) 2019-04-04
JP2020536055A (ja) 2020-12-10
WO2019067523A1 (en) 2019-04-04
KR20200079237A (ko) 2020-07-02

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