MX2019012968A - Nicotinamida de liberacion modificada. - Google Patents

Nicotinamida de liberacion modificada.

Info

Publication number
MX2019012968A
MX2019012968A MX2019012968A MX2019012968A MX2019012968A MX 2019012968 A MX2019012968 A MX 2019012968A MX 2019012968 A MX2019012968 A MX 2019012968A MX 2019012968 A MX2019012968 A MX 2019012968A MX 2019012968 A MX2019012968 A MX 2019012968A
Authority
MX
Mexico
Prior art keywords
modified release
release nicotinamide
nicotinamide
hyperphosphatemia
dyslipidemia
Prior art date
Application number
MX2019012968A
Other languages
English (en)
Inventor
Richard Ammer
Original Assignee
Salmon Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salmon Pharma Gmbh filed Critical Salmon Pharma Gmbh
Publication of MX2019012968A publication Critical patent/MX2019012968A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/244—Lanthanides; Compounds thereof

Abstract

La presente invención se refiere a una preparación farmacéutica que comprende nicotinamida de liberación modificada, así como a su uso en un método de prevención y/o tratamiento de niveles elevados de fosfato en suero (hiperfosfatemia) y/o dislipidemia, ambos particularmente resultantes de insuficiencia renal.
MX2019012968A 2017-05-02 2018-05-02 Nicotinamida de liberacion modificada. MX2019012968A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17168957.3A EP3398600A1 (en) 2017-05-02 2017-05-02 Modified release nicotinamide
PCT/EP2018/061202 WO2018202708A1 (en) 2017-05-02 2018-05-02 Modified release nicotinamide

Publications (1)

Publication Number Publication Date
MX2019012968A true MX2019012968A (es) 2020-08-17

Family

ID=58664561

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019012968A MX2019012968A (es) 2017-05-02 2018-05-02 Nicotinamida de liberacion modificada.

Country Status (11)

Country Link
US (1) US20180318280A1 (es)
EP (2) EP3398600A1 (es)
JP (1) JP2020518637A (es)
KR (1) KR20190141773A (es)
CN (1) CN110913860A (es)
BR (1) BR112019022883A2 (es)
CA (1) CA3060214A1 (es)
MA (1) MA49044A (es)
MX (1) MX2019012968A (es)
RU (1) RU2019134848A (es)
WO (1) WO2018202708A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020235643A1 (en) 2019-03-14 2021-09-30 Augusta University Research Institute, Inc. Methods and compositions for supporting renal health
CN115837023B (zh) * 2023-02-20 2023-05-16 中山大学附属第八医院（深圳福田） 1-甲基烟酰胺在制备抗血管钙化药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1935422A1 (en) * 2006-12-20 2008-06-25 PEJO Iserlohn Heilmittel-und Diät-GmbH & Co.KG Pharmaceutical composition comprising nicotinamide or nicotinic acid
EP2731609A1 (en) * 2011-07-14 2014-05-21 APeT Holding B.V. Nicotinamide compositions and the therapeutic use thereof
ES2785399T3 (es) * 2013-06-14 2020-10-06 Conaris Res Institute Ag Formulación de nicotinamida de liberación prolongada
HUE048488T2 (hu) * 2013-12-13 2020-07-28 Conaris Res Institute Ag Nikotinsavat és/vagy nikotinamidot tartalmazó gyógyászati készítmény a vérlipid szint jótékony hatású befolyására történõ alkalmazásra a bélrendszeri mikrobióta módosításával
CN104825451A (zh) * 2015-05-14 2015-08-12 徐州恒鼎生物科技有限公司 一种美白祛斑维生素b3缓释制剂

Also Published As

Publication number Publication date
EP3398600A1 (en) 2018-11-07
MA49044A (fr) 2020-02-12
CN110913860A (zh) 2020-03-24
WO2018202708A1 (en) 2018-11-08
RU2019134848A (ru) 2021-04-30
KR20190141773A (ko) 2019-12-24
EP3606526A1 (en) 2020-02-12
RU2019134848A3 (es) 2021-04-30
JP2020518637A (ja) 2020-06-25
CA3060214A1 (en) 2018-11-08
US20180318280A1 (en) 2018-11-08
BR112019022883A2 (pt) 2020-05-19

Similar Documents

Publication Publication Date Title
EP3398948A3 (en) 2,4,6,7-tetrasubstituted pteridine compounds and methods of synthesis and use thereof
PH12017501342A1 (en) Glycan therapeutics and related methods thereof
BR112018004620A2 (pt) moduladores da expressão de kras
AU2016261707A8 (en) Use of cannabis to treat fibromyalgia, methods and compositions thereof
WO2017059319A3 (en) Combination therapy of bromodomain inhibitors and checkpoint blockade
TW201614068A (en) Fucosidase from bacteroides and methods using the same
MX2016014807A (es) Singenes de alfa(1,2)fucosiltransferasa para su utilizacion en la produccion de oligosacaridos fucosilados.
MX2018005829A (es) Composiciones para tratar el cabello.
GB2538178A (en) Viscosifier polymer for treatment of a subterranean formation
SG10201808940WA (en) Nox inhibitor and nfкb inhibitor containing methoxyflavone
MX2014011825A (es) INHIBIDORES DE ISOXAZOL ß-LACTAMASA.
EA033325B1 (ru) Ингибиторы бромодомена
MX2018008402A (es) Uso de 4-bora-3a,4a-diaza-s-indacenos para fines de seguridad.
PH12019501018A1 (en) Pharmaceutical composition, methods for treating and uses thereof
PH12019501199A1 (en) Calcium lactate compositions and methods of use
PH12016502002B1 (en) Novel bacteriophage and composition comprising same
MX2020002123A (es) Sales de ribociclib y formas en estado sólido de las mismas.
MX2017014095A (es) Uso de cd24 para disminuir los niveles de colesterol de las lipoproteinas de baja densidad.
MX2017005249A (es) Compuestos para usarse en el tratamiento antihelmintico.
MX2019012968A (es) Nicotinamida de liberacion modificada.
WO2016193941A3 (en) Testing of a medical fluid treatment system
PH12017501735A1 (en) Novel heterocyclic compound, method for preparing the same, and pharmaceutical composition comprising the same
PH12016502322B1 (en) Compounds and methods for preventing or treating malaria
MX2019012970A (es) Nicotinamida para tratar dislipidemia.
MX2017001047A (es) Compuestos para usar en el tratamiento antihelmintico.